5C16
Myotubularin-related proetin 1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0046856 | biological_process | phosphatidylinositol dephosphorylation |
| A | 0052866 | molecular_function | phosphatidylinositol phosphate phosphatase activity |
| B | 0046856 | biological_process | phosphatidylinositol dephosphorylation |
| B | 0052866 | molecular_function | phosphatidylinositol phosphate phosphatase activity |
| C | 0046856 | biological_process | phosphatidylinositol dephosphorylation |
| C | 0052866 | molecular_function | phosphatidylinositol phosphate phosphatase activity |
| D | 0046856 | biological_process | phosphatidylinositol dephosphorylation |
| D | 0052866 | molecular_function | phosphatidylinositol phosphate phosphatase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue PO4 A 701 |
| Chain | Residue |
| A | SER438 |
| A | SER439 |
| A | ASP440 |
| A | GLY441 |
| A | TRP442 |
| A | ASP443 |
| A | ARG444 |
| A | HOH935 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 A 702 |
| Chain | Residue |
| A | ASN376 |
| A | SER439 |
| A | ARG444 |
| A | HOH926 |
| A | ASN351 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue PO4 B 701 |
| Chain | Residue |
| B | SER438 |
| B | SER439 |
| B | ASP440 |
| B | GLY441 |
| B | TRP442 |
| B | ASP443 |
| B | ARG444 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue PO4 B 702 |
| Chain | Residue |
| B | VAL347 |
| B | ASN351 |
| B | ASN376 |
| B | SER439 |
| B | ARG444 |
| B | HOH905 |
| B | HOH909 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue PO4 C 701 |
| Chain | Residue |
| C | SER438 |
| C | SER439 |
| C | ASP440 |
| C | GLY441 |
| C | TRP442 |
| C | ASP443 |
| C | ARG444 |
| C | HOH807 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue PO4 D 701 |
| Chain | Residue |
| D | SER438 |
| D | SER439 |
| D | ASP440 |
| D | GLY441 |
| D | TRP442 |
| D | ASP443 |
| D | ARG444 |
| D | HOH837 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1500 |
| Details | Domain: {"description":"Myotubularin phosphatase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00669","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Phosphocysteine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU10044","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"27018598","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q13614","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27018598","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5C16","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
