5BZT

Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005540	molecular_function	hyaluronic acid binding
A	0007155	biological_process	cell adhesion
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue DMS A 201

Chain	Residue
A	CYS32
A	ASN89
A	CYS134
A	SER136
A	ARG155
A	ASP156
A	HOH307
A	HOH322

---

site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 A 202

Chain	Residue
A	PHE38
A	PHE60
A	ASN125
A	VAL137
A	ARG33

---

site_id	AC3
Number of Residues	11
Details	binding site for residue 4XJ A 203

Chain	Residue
A	ASN29
A	VAL30
A	HIS39
A	GLU41
A	ASP68
A	VAL153
A	ASN154
A	ARG155
A	HOH343
A	HOH364
A	HOH379

---

site_id	AC4
Number of Residues	3
Details	binding site for residue 4XJ A 204

Chain	Residue
A	ASP145
A	GLY146
A	HOH324

---

site_id	AC5
Number of Residues	7
Details	binding site for residue GOL A 205

Chain	Residue
A	TYR46
A	CYS81
A	ILE92
A	ILE100
A	ALA102
A	GLU131
A	HOH332

---

Functional Information from PROSITE/UniProt

site_id	PS01241
Number of Residues	45
Details	LINK_1 Link domain signature. CqafnstlptmdqmklAlsk.GfetCryGfiegnvvi.PrihpnaiC

Chain	Residue	Details
A	CYS57-CYS101

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	89
Details	Domain: {"description":"Link","evidences":[{"source":"PROSITE-ProRule","id":"PRU00323","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17293874","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	5
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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