Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5BZ4

Crystal structure of a T1-like thiolase (CoA-complex) from Mycobacterium smegmatis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
A	0005829	cellular_component	cytosol
A	0006635	biological_process	fatty acid beta-oxidation
A	0016746	molecular_function	acyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
B	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
B	0005829	cellular_component	cytosol
B	0006635	biological_process	fatty acid beta-oxidation
B	0016746	molecular_function	acyltransferase activity
B	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
C	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
C	0005829	cellular_component	cytosol
C	0006635	biological_process	fatty acid beta-oxidation
C	0016746	molecular_function	acyltransferase activity
C	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
D	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
D	0005829	cellular_component	cytosol
D	0006635	biological_process	fatty acid beta-oxidation
D	0016746	molecular_function	acyltransferase activity
D	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
E	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
E	0005829	cellular_component	cytosol
E	0006635	biological_process	fatty acid beta-oxidation
E	0016746	molecular_function	acyltransferase activity
E	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
F	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
F	0005829	cellular_component	cytosol
F	0006635	biological_process	fatty acid beta-oxidation
F	0016746	molecular_function	acyltransferase activity
F	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
G	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
G	0005829	cellular_component	cytosol
G	0006635	biological_process	fatty acid beta-oxidation
G	0016746	molecular_function	acyltransferase activity
G	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
H	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
H	0005829	cellular_component	cytosol
H	0006635	biological_process	fatty acid beta-oxidation
H	0016746	molecular_function	acyltransferase activity
H	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
J	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
J	0005829	cellular_component	cytosol
J	0006635	biological_process	fatty acid beta-oxidation
J	0016746	molecular_function	acyltransferase activity
J	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
K	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
K	0005829	cellular_component	cytosol
K	0006635	biological_process	fatty acid beta-oxidation
K	0016746	molecular_function	acyltransferase activity
K	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
L	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
L	0005829	cellular_component	cytosol
L	0006635	biological_process	fatty acid beta-oxidation
L	0016746	molecular_function	acyltransferase activity
L	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
M	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
M	0005829	cellular_component	cytosol
M	0006635	biological_process	fatty acid beta-oxidation
M	0016746	molecular_function	acyltransferase activity
M	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue COA B 501

Chain	Residue
B	CYS90
B	HOH609
B	HOH639
B	HOH671
B	HOH686
B	HOH696
B	ARG149
B	ARG226
B	LEU234
B	ALA252
B	GLY253
B	SER256
B	GLN258
B	HIS360

site_id	AC2
Number of Residues	16
Details	binding site for residue COA D 501

Chain	Residue
A	ARG136
D	CYS90
D	MET163
D	ALA233
D	LEU234
D	LEU237
D	ALA252
D	SER256
D	GLN258
D	ALA327
D	PHE328
D	HIS360
D	HOH638
D	HOH668
D	HOH682
D	HOH705

site_id	AC3
Number of Residues	15
Details	binding site for residue COA F 501

Chain	Residue
F	CYS90
F	MET163
F	HIS189
F	THR229
F	LEU234
F	ALA252
F	SER256
F	GLN258
F	ALA327
F	PHE328
F	HIS360
F	HOH606
F	HOH638
F	HOH657
G	ARG136

site_id	AC4
Number of Residues	13
Details	binding site for residue COA H 501

Chain	Residue
E	ARG136
H	CYS90
H	MET163
H	LEU164
H	ALA252
H	GLY253
H	SER256
H	GLN258
H	HIS360
H	HOH602
H	HOH616
H	HOH644
H	HOH670

site_id	AC5
Number of Residues	16
Details	binding site for residue COA K 501

Chain	Residue
K	CYS90
K	ARG149
K	MET163
K	ARG226
K	LEU237
K	ALA252
K	GLY253
K	SER256
K	GLN258
K	ALA327
K	PHE328
K	HIS360
K	HOH652
K	HOH654
K	HOH697
L	ARG136

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)