5BY9

The crystal structure of polyglycilated 14-3-3 protein from Giardia intestinalis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000165	biological_process	MAPK cascade
A	0003779	molecular_function	actin binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005635	cellular_component	nuclear envelope
A	0005737	cellular_component	cytoplasm
A	0005783	cellular_component	endoplasmic reticulum
A	0005819	cellular_component	spindle
A	0005856	cellular_component	cytoskeleton
A	0005929	cellular_component	cilium
A	0005930	cellular_component	axoneme
A	0007165	biological_process	signal transduction
A	0008104	biological_process	protein localization
A	0019900	molecular_function	kinase binding
A	0030010	biological_process	establishment of cell polarity
A	0030036	biological_process	actin cytoskeleton organization
A	0031514	cellular_component	motile cilium
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0042995	cellular_component	cell projection
A	0050815	molecular_function	phosphoserine residue binding
A	0051219	molecular_function	phosphoprotein binding
A	0051289	biological_process	protein homotetramerization
A	0051495	biological_process	positive regulation of cytoskeleton organization
A	0070207	biological_process	protein homotrimerization
A	0097298	biological_process	regulation of nucleus size
B	0000165	biological_process	MAPK cascade
B	0003779	molecular_function	actin binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005635	cellular_component	nuclear envelope
B	0005737	cellular_component	cytoplasm
B	0005783	cellular_component	endoplasmic reticulum
B	0005819	cellular_component	spindle
B	0005856	cellular_component	cytoskeleton
B	0005929	cellular_component	cilium
B	0005930	cellular_component	axoneme
B	0007165	biological_process	signal transduction
B	0008104	biological_process	protein localization
B	0019900	molecular_function	kinase binding
B	0030010	biological_process	establishment of cell polarity
B	0030036	biological_process	actin cytoskeleton organization
B	0031514	cellular_component	motile cilium
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0042995	cellular_component	cell projection
B	0050815	molecular_function	phosphoserine residue binding
B	0051219	molecular_function	phosphoprotein binding
B	0051289	biological_process	protein homotetramerization
B	0051495	biological_process	positive regulation of cytoskeleton organization
B	0070207	biological_process	protein homotrimerization
B	0097298	biological_process	regulation of nucleus size
C	0000165	biological_process	MAPK cascade
C	0003779	molecular_function	actin binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005635	cellular_component	nuclear envelope
C	0005737	cellular_component	cytoplasm
C	0005783	cellular_component	endoplasmic reticulum
C	0005819	cellular_component	spindle
C	0005856	cellular_component	cytoskeleton
C	0005929	cellular_component	cilium
C	0005930	cellular_component	axoneme
C	0007165	biological_process	signal transduction
C	0008104	biological_process	protein localization
C	0019900	molecular_function	kinase binding
C	0030010	biological_process	establishment of cell polarity
C	0030036	biological_process	actin cytoskeleton organization
C	0031514	cellular_component	motile cilium
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
C	0042995	cellular_component	cell projection
C	0050815	molecular_function	phosphoserine residue binding
C	0051219	molecular_function	phosphoprotein binding
C	0051289	biological_process	protein homotetramerization
C	0051495	biological_process	positive regulation of cytoskeleton organization
C	0070207	biological_process	protein homotrimerization
C	0097298	biological_process	regulation of nucleus size
D	0000165	biological_process	MAPK cascade
D	0003779	molecular_function	actin binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005635	cellular_component	nuclear envelope
D	0005737	cellular_component	cytoplasm
D	0005783	cellular_component	endoplasmic reticulum
D	0005819	cellular_component	spindle
D	0005856	cellular_component	cytoskeleton
D	0005929	cellular_component	cilium
D	0005930	cellular_component	axoneme
D	0007165	biological_process	signal transduction
D	0008104	biological_process	protein localization
D	0019900	molecular_function	kinase binding
D	0030010	biological_process	establishment of cell polarity
D	0030036	biological_process	actin cytoskeleton organization
D	0031514	cellular_component	motile cilium
D	0042802	molecular_function	identical protein binding
D	0042803	molecular_function	protein homodimerization activity
D	0042995	cellular_component	cell projection
D	0050815	molecular_function	phosphoserine residue binding
D	0051219	molecular_function	phosphoprotein binding
D	0051289	biological_process	protein homotetramerization
D	0051495	biological_process	positive regulation of cytoskeleton organization
D	0070207	biological_process	protein homotrimerization
D	0097298	biological_process	regulation of nucleus size

Functional Information from PROSITE/UniProt

site_id	PS00796
Number of Residues	11
Details	1433_1 14-3-3 proteins signature 1. RNLLSVAYKNV

Chain	Residue	Details
A	ARG45-VAL55

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	160
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26551337","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4ZQ0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Site: {"description":"Interaction with phosphoserine","evidences":[{"source":"PubMed","id":"26551337","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4ZQ0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"16368691","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19733174","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24147113","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24658679","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---