5BX3

Crystal structure of Thermoanaerobacterium xylanolyticum GH116 beta-glucosidase with deoxynojirimycin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004348	molecular_function	glucosylceramidase activity
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0005975	biological_process	carbohydrate metabolic process
A	0006680	biological_process	glucosylceramide catabolic process
A	0008152	biological_process	metabolic process
A	0008422	molecular_function	beta-glucosidase activity
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue NOJ A 901

Chain	Residue
A	GLU441
A	GLU777
A	ARG786
A	TYR790
A	ARG792
A	TYR445
A	ASP452
A	HIS507
A	TYR523
A	TRP531
A	THR591
A	ASP593
A	TRP732

---

site_id	AC2
Number of Residues	4
Details	binding site for residue GOL A 902

Chain	Residue
A	ARG432
A	THR433
A	ASN434
A	GOL909

---

site_id	AC3
Number of Residues	5
Details	binding site for residue GOL A 903

Chain	Residue
A	TRP421
A	ASN434
A	ASN435
A	GLN471
A	HOH1209

---

site_id	AC4
Number of Residues	4
Details	binding site for residue GOL A 904

Chain	Residue
A	GLY362
A	LYS363
A	ASN364
A	HOH1092

---

site_id	AC5
Number of Residues	7
Details	binding site for residue GOL A 905

Chain	Residue
A	TRP595
A	SER596
A	PHE654
A	SER658
A	HIS660
A	ASP722
A	SER724

---

site_id	AC6
Number of Residues	6
Details	binding site for residue GOL A 906

Chain	Residue
A	ASP38
A	TRP160
A	LYS175
A	ASP387
A	GOL912
A	HOH1125

---

site_id	AC7
Number of Residues	8
Details	binding site for residue GOL A 907

Chain	Residue
A	TRP44
A	THR45
A	ILE46
A	GLU50
A	TYR764
A	ASP765
A	LYS766
A	TRP772

---

site_id	AC8
Number of Residues	4
Details	binding site for residue GOL A 908

Chain	Residue
A	THR566
A	ASP569
A	LYS570
A	HOH1068

---

site_id	AC9
Number of Residues	7
Details	binding site for residue GOL A 909

Chain	Residue
A	ASN434
A	GLN471
A	ARG474
A	GLN475
A	ASP478
A	TYR559
A	GOL902

---

site_id	AD1
Number of Residues	4
Details	binding site for residue GOL A 910

Chain	Residue
A	TYR445
A	ASP593
A	GLN727
A	HOH1002

---

site_id	AD2
Number of Residues	5
Details	binding site for residue GOL A 911

Chain	Residue
A	ASP484
A	ILE518
A	LYS519
A	ILE520
A	HOH1324

---

site_id	AD3
Number of Residues	6
Details	binding site for residue GOL A 912

Chain	Residue
A	LYS175
A	LYS196
A	GLU383
A	ASP387
A	GOL906
A	HOH1015

---

site_id	AD4
Number of Residues	10
Details	binding site for residue GOL A 913

Chain	Residue
A	ASP577
A	ASP579
A	ASP583
A	GLY599
A	THR600
A	GLU645
A	THR656
A	GLU657
A	CA917
A	HOH1123

---

site_id	AD5
Number of Residues	7
Details	binding site for residue GOL A 914

Chain	Residue
A	ILE181
A	PRO182
A	TYR183
A	ASN184
A	MET385
A	GLU723
A	HOH1127

---

site_id	AD6
Number of Residues	3
Details	binding site for residue GOL A 915

Chain	Residue
A	TRP647
A	GLY649
A	HIS688

---

site_id	AD7
Number of Residues	5
Details	binding site for residue GOL A 916

Chain	Residue
A	VAL60
A	LYS61
A	TYR62
A	LYS312
A	HOH1005

---

site_id	AD8
Number of Residues	7
Details	binding site for residue CA A 917

Chain	Residue
A	ASP577
A	ASP579
A	ILE581
A	ASP583
A	GOL913
A	HOH1123
A	ASP575

---

site_id	AD9
Number of Residues	11
Details	binding site for residue EDO A 918

Chain	Residue
A	GLY81
A	THR82
A	HIS95
A	ILE98
A	ALA415
A	ASP416
A	GLY417
A	GLY418
A	THR419
A	HOH1019
A	HOH1140

---