5BV5
Structure of CYP119 with T213A and C317H mutations
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| A | 0140825 | molecular_function | lactoperoxidase activity |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| B | 0020037 | molecular_function | heme binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0140825 | molecular_function | lactoperoxidase activity |
| C | 0004497 | molecular_function | monooxygenase activity |
| C | 0004601 | molecular_function | peroxidase activity |
| C | 0005506 | molecular_function | iron ion binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| C | 0020037 | molecular_function | heme binding |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0098869 | biological_process | cellular oxidant detoxification |
| C | 0140825 | molecular_function | lactoperoxidase activity |
| D | 0004497 | molecular_function | monooxygenase activity |
| D | 0004601 | molecular_function | peroxidase activity |
| D | 0005506 | molecular_function | iron ion binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| D | 0020037 | molecular_function | heme binding |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0098869 | biological_process | cellular oxidant detoxification |
| D | 0140825 | molecular_function | lactoperoxidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 A 601 |
| Chain | Residue |
| A | MET1 |
| A | TYR2 |
| C | MET1 |
| C | TYR2 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue HEM A 602 |
| Chain | Residue |
| A | VAL254 |
| A | THR257 |
| A | ARG259 |
| A | SER309 |
| A | PHE310 |
| A | SER312 |
| A | HIS317 |
| A | ALA323 |
| A | HOH701 |
| A | LEU207 |
| A | GLY210 |
| A | ASN211 |
| A | ALA213 |
| A | THR214 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 B 601 |
| Chain | Residue |
| B | MET1 |
| B | TYR2 |
| B | ASP3 |
| D | MET1 |
| D | TYR2 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | binding site for residue HEM B 602 |
| Chain | Residue |
| B | LEU207 |
| B | GLY210 |
| B | ALA213 |
| B | THR214 |
| B | THR257 |
| B | ARG259 |
| B | SER309 |
| B | PHE310 |
| B | GLY311 |
| B | HIS317 |
| B | GLY319 |
| B | ALA323 |
| B | PIM603 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue PIM B 603 |
| Chain | Residue |
| B | GLY210 |
| B | ALA213 |
| B | LEU354 |
| B | HEM602 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | binding site for residue HEM D 500 |
| Chain | Residue |
| D | SER41 |
| D | HIS76 |
| D | LEU79 |
| D | LEU207 |
| D | GLY210 |
| D | ASN211 |
| D | ALA213 |
| D | LEU217 |
| D | THR257 |
| D | ARG259 |
| D | ILE282 |
| D | SER309 |
| D | PHE310 |
| D | SER312 |
| D | HIS317 |
| D | PIM501 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue PIM D 501 |
| Chain | Residue |
| D | GLY210 |
| D | ALA213 |
| D | HEM500 |
| site_id | AC8 |
| Number of Residues | 16 |
| Details | binding site for residue HEM C 500 |
| Chain | Residue |
| C | LEU33 |
| C | HIS76 |
| C | LEU207 |
| C | GLY210 |
| C | ASN211 |
| C | ALA213 |
| C | VAL254 |
| C | THR257 |
| C | ARG259 |
| C | ILE282 |
| C | SER309 |
| C | PHE310 |
| C | GLY311 |
| C | SER312 |
| C | HIS317 |
| C | PIM501 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue PIM C 501 |
| Chain | Residue |
| C | GLY210 |
| C | ALA213 |
| C | HEM500 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10859321","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10957637","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"description":"axial binding residue"} |
| Chain | Residue | Details |
