5BT9

Crystal Structure of FolM Alternative dihydrofolate reductase 1 from Brucella canis complexed with NADP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0016491	molecular_function	oxidoreductase activity
B	0000166	molecular_function	nucleotide binding
B	0016491	molecular_function	oxidoreductase activity
C	0000166	molecular_function	nucleotide binding
C	0016491	molecular_function	oxidoreductase activity
D	0000166	molecular_function	nucleotide binding
D	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	30
Details	binding site for residue NAP A 300

Chain	Residue
A	GLY19
A	ASP70
A	LEU71
A	GLU72
A	ASN95
A	ALA96
A	SER97
A	ILE145
A	ILE146
A	TYR160
A	LYS164
A	ARG23
A	PRO189
A	GLY190
A	THR192
A	LEU193
A	HOH409
A	HOH442
A	HOH445
A	HOH452
A	HOH461
A	HOH489
A	ILE24
A	HOH526
A	HIS42
A	CYS43
A	ASN44
A	ARG45
A	SER46
A	ALA69

---

site_id	AC2
Number of Residues	29
Details	binding site for residue NAP B 300

Chain	Residue
B	ARG23
B	ILE24
B	HIS42
B	CYS43
B	ASN44
B	ARG45
B	SER46
B	ALA69
B	ASP70
B	LEU71
B	GLU72
B	ASN95
B	ALA96
B	SER97
B	ILE145
B	ILE146
B	TYR160
B	LYS164
B	PRO189
B	GLY190
B	THR192
B	HOH405
B	HOH412
B	HOH420
B	HOH423
B	HOH431
B	HOH476
B	HOH482
B	HOH507

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site_id	AC3
Number of Residues	26
Details	binding site for residue NAP C 300

Chain	Residue
C	ARG23
C	ILE24
C	HIS42
C	CYS43
C	ASN44
C	ARG45
C	SER46
C	ALA69
C	LEU71
C	GLU72
C	ASN95
C	ALA96
C	SER97
C	VAL118
C	ILE145
C	ILE146
C	TYR160
C	LYS164
C	PRO189
C	GLY190
C	THR192
C	LEU193
C	HOH404
C	HOH436
C	HOH497
C	HOH500

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site_id	AC4
Number of Residues	30
Details	binding site for residue NAP D 300

Chain	Residue
D	ILE145
D	ILE146
D	TYR160
D	LYS164
D	PRO189
D	GLY190
D	THR192
D	HOH418
D	HOH430
D	HOH432
D	HOH444
D	HOH450
D	HOH452
D	HOH464
D	HOH474
D	HOH539
D	ARG23
D	ILE24
D	HIS42
D	CYS43
D	ASN44
D	ARG45
D	SER46
D	ALA69
D	ASP70
D	LEU71
D	GLU72
D	ASN95
D	ALA96
D	SER97

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