5BQS
S. Pneumoniae Fabh with small molecule inhibitor 4
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0033818 | molecular_function | beta-ketoacyl-acyl-carrier-protein synthase III activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0033818 | molecular_function | beta-ketoacyl-acyl-carrier-protein synthase III activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 401 |
| Chain | Residue |
| A | ILE233 |
| A | ASP234 |
| A | SER236 |
| A | ILE238 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue 4VN A 402 |
| Chain | Residue |
| A | VAL217 |
| A | HIS249 |
| A | ALA251 |
| A | ARG254 |
| A | ILE255 |
| A | ASN279 |
| A | PHE311 |
| A | HOH524 |
| A | ARG37 |
| A | CYS112 |
| A | PHE157 |
| A | MET212 |
| A | GLY214 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue NA B 401 |
| Chain | Residue |
| B | ILE233 |
| B | ASP234 |
| B | SER236 |
| B | ILE238 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | binding site for residue 4VN B 402 |
| Chain | Residue |
| B | ARG37 |
| B | CYS112 |
| B | PHE157 |
| B | LEU189 |
| B | MET212 |
| B | GLY214 |
| B | VAL217 |
| B | HIS249 |
| B | ALA251 |
| B | ASN252 |
| B | ARG254 |
| B | ILE255 |
| B | ASN279 |
| B | PHE311 |
| B | HOH543 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Region: {"description":"ACP-binding","evidences":[{"source":"HAMAP-Rule","id":"MF_01815","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01815","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
