5BQD
Crystal Structure of TBX5 (1-239) Dimer
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000978 | molecular_function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
A | 0003700 | molecular_function | DNA-binding transcription factor activity |
A | 0005634 | cellular_component | nucleus |
A | 0006355 | biological_process | regulation of DNA-templated transcription |
A | 0045893 | biological_process | positive regulation of DNA-templated transcription |
B | 0000978 | molecular_function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
B | 0003700 | molecular_function | DNA-binding transcription factor activity |
B | 0005634 | cellular_component | nucleus |
B | 0006355 | biological_process | regulation of DNA-templated transcription |
B | 0045893 | biological_process | positive regulation of DNA-templated transcription |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 3 |
Details | binding site for residue MG B 301 |
Chain | Residue |
A | HOH308 |
B | ILE75 |
B | ARG81 |
site_id | AC2 |
Number of Residues | 1 |
Details | binding site for residue MG B 302 |
Chain | Residue |
B | ARG81 |
site_id | AC3 |
Number of Residues | 3 |
Details | binding site for residue MG B 303 |
Chain | Residue |
A | ASN119 |
B | THR77 |
B | ARG81 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 360 |
Details | DNA_BIND: T-box => ECO:0000255|PROSITE-ProRule:PRU00201, ECO:0000269|PubMed:26926761 |
Chain | Residue | Details |
A | LEU58-GLY238 | |
B | LEU58-GLY238 |