5BQD

Crystal Structure of TBX5 (1-239) Dimer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000978	molecular_function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005634	cellular_component	nucleus
A	0006355	biological_process	regulation of DNA-templated transcription
A	0045893	biological_process	positive regulation of DNA-templated transcription
B	0000978	molecular_function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0005634	cellular_component	nucleus
B	0006355	biological_process	regulation of DNA-templated transcription
B	0045893	biological_process	positive regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue MG B 301

Chain	Residue
A	HOH308
B	ILE75
B	ARG81

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site_id	AC2
Number of Residues	1
Details	binding site for residue MG B 302

Chain	Residue
B	ARG81

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site_id	AC3
Number of Residues	3
Details	binding site for residue MG B 303

Chain	Residue
A	ASN119
B	THR77
B	ARG81

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Functional Information from PROSITE/UniProt

site_id	PS01264
Number of Residues	19
Details	TBOX_2 T-box domain signature 2. VHPDSpatGahWMrqlVsF

Chain	Residue	Details
A	VAL137-PHE155

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site_id	PS01283
Number of Residues	20
Details	TBOX_1 T-box domain signature 1. LWlkFhevgTEMIITkaGRR

Chain	Residue	Details
A	LEU63-ARG82

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