5BOZ

Ricin A chain bound to camelid nanobody (VHH9)(E1)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0017148	biological_process	negative regulation of translation
A	0030598	molecular_function	rRNA N-glycosylase activity
B	0017148	biological_process	negative regulation of translation
B	0030598	molecular_function	rRNA N-glycosylase activity
C	0017148	biological_process	negative regulation of translation
C	0030598	molecular_function	rRNA N-glycosylase activity
D	0017148	biological_process	negative regulation of translation
D	0030598	molecular_function	rRNA N-glycosylase activity
E	0017148	biological_process	negative regulation of translation
E	0030598	molecular_function	rRNA N-glycosylase activity
F	0017148	biological_process	negative regulation of translation
F	0030598	molecular_function	rRNA N-glycosylase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue SO4 A 301

Chain	Residue
A	PHE119
A	GLY120
A	ASN122
A	ARG125

---

site_id	AC2
Number of Residues	3
Details	binding site for residue SO4 A 302

Chain	Residue
A	ARG125
A	GLN128
H	LYS43

---

site_id	AC3
Number of Residues	3
Details	binding site for residue SO4 G 201

Chain	Residue
A	GLY87
A	GLU61
A	ARG85

---

site_id	AC4
Number of Residues	4
Details	binding site for residue SO4 B 301

Chain	Residue
B	PHE119
B	GLY120
B	ASN122
B	ARG125

---

site_id	AC5
Number of Residues	3
Details	binding site for residue SO4 B 302

Chain	Residue
B	GLY142
B	ARG197
H	SER30

---

site_id	AC6
Number of Residues	4
Details	binding site for residue SO4 B 303

Chain	Residue
B	GLU61
B	ARG85
B	GLY87
H	GLY8

---

site_id	AC7
Number of Residues	3
Details	binding site for residue SO4 B 304

Chain	Residue
B	ARG189
B	THR190
B	ARG193

---

site_id	AC8
Number of Residues	1
Details	binding site for residue SO4 B 305

Chain	Residue
B	ARG125

---

site_id	AC9
Number of Residues	5
Details	binding site for residue SO4 C 301

Chain	Residue
C	PHE119
C	GLY120
C	ASN122
C	ARG125
C	HOH403

---

site_id	AD1
Number of Residues	1
Details	binding site for residue SO4 C 302

Chain	Residue
C	ARG125

---

site_id	AD2
Number of Residues	2
Details	binding site for residue SO4 C 303

Chain	Residue
C	TYR115
D	TYR115

---

site_id	AD3
Number of Residues	3
Details	binding site for residue SO4 I 201

Chain	Residue
D	ARG85
I	SER7
I	GLY8

---

site_id	AD4
Number of Residues	1
Details	binding site for residue SO4 D 301

Chain	Residue
D	ARG125

---

site_id	AD5
Number of Residues	1
Details	binding site for residue CL D 302

Chain	Residue
D	ARG125

---

site_id	AD6
Number of Residues	5
Details	binding site for residue SO4 J 201

Chain	Residue
C	ARG85
C	GLY87
J	SER7
J	GLY8
J	THR120

---

site_id	AD7
Number of Residues	4
Details	binding site for residue SO4 E 301

Chain	Residue
E	ARG85
E	GLY87
K	SER7
K	GLY8

---

site_id	AD8
Number of Residues	3
Details	binding site for residue SO4 E 302

Chain	Residue
E	GLY142
E	ARG197
K	SER30

---

site_id	AD9
Number of Residues	3
Details	binding site for residue SO4 E 303

Chain	Residue
E	ARG125
E	GLN128
K	LYS43

---

site_id	AE1
Number of Residues	2
Details	binding site for residue CL E 304

Chain	Residue
E	GLY120
E	ARG125

---

site_id	AE2
Number of Residues	2
Details	binding site for residue CL K 201

Chain	Residue
K	THR58
K	TYR60

---

site_id	AE3
Number of Residues	4
Details	binding site for residue SO4 F 301

Chain	Residue
F	PHE119
F	GLY120
F	ASN122
F	ARG125

---

site_id	AE4
Number of Residues	2
Details	binding site for residue SO4 F 302

Chain	Residue
F	ARG125
L	LYS43

---

site_id	AE5
Number of Residues	4
Details	binding site for residue SO4 L 201

Chain	Residue
F	ARG85
F	GLY87
L	SER7
L	GLY8

---

Functional Information from PROSITE/UniProt

site_id	PS00275
Number of Residues	17
Details	SHIGA_RICIN Shiga/ricin ribosomal inactivating toxins active site signature. IqMIsEAARFQyIEgeM

Chain	Residue	Details
A	ILE172-MET188

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	Active site: {"evidences":[{"source":"UniProtKB","id":"P84531","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	54
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"PubMed","id":"8780513","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OBT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","featureId":"CAR_000080","evidences":[{"source":"PubMed","id":"1368517","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; partial","featureId":"CAR_000081","evidences":[{"source":"PubMed","id":"1368517","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---