5BOW
CRYSTAL STRUCTURE OF IL-38
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002437 | biological_process | inflammatory response to antigenic stimulus |
| A | 0005125 | molecular_function | cytokine activity |
| A | 0005149 | molecular_function | interleukin-1 receptor binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006954 | biological_process | inflammatory response |
| A | 0006955 | biological_process | immune response |
| A | 0010628 | biological_process | positive regulation of gene expression |
| A | 0019221 | biological_process | cytokine-mediated signaling pathway |
| A | 0071222 | biological_process | cellular response to lipopolysaccharide |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 201 |
| Chain | Residue |
| A | THR135 |
| A | THR135 |
| A | LYS136 |
| A | LYS136 |
| A | HOH328 |
| A | HOH328 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 202 |
| Chain | Residue |
| A | SER151 |
| A | TRP152 |
| A | HOH308 |
| A | HOH310 |
| A | HOH373 |
| A | ALA34 |
| A | ASN36 |
| A | GLN150 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 203 |
| Chain | Residue |
| A | TYR9 |
| A | GLY63 |
| A | GLU87 |
| A | HOH317 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 204 |
| Chain | Residue |
| A | THR53 |
| A | GLU75 |
| A | PRO77 |
| A | LEU134 |
| A | HOH337 |
| A | HOH341 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 205 |
| Chain | Residue |
| A | TYR21 |
| A | VAL29 |
| A | PRO128 |
| A | GLN129 |
| A | HOH307 |
| A | HOH345 |
| A | HOH361 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 206 |
| Chain | Residue |
| A | LYS13 |
| A | ALA19 |
| A | GLY107 |
| A | SER108 |
| A | HOH302 |
