5BOW

CRYSTAL STRUCTURE OF IL-38

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005125	molecular_function	cytokine activity
A	0005149	molecular_function	interleukin-1 receptor binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005737	cellular_component	cytoplasm
A	0006954	biological_process	inflammatory response
A	0006955	biological_process	immune response
A	0019221	biological_process	cytokine-mediated signaling pathway
A	0071222	biological_process	cellular response to lipopolysaccharide

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue EDO A 201

Chain	Residue
A	THR135
A	THR135
A	LYS136
A	LYS136
A	HOH328
A	HOH328

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site_id	AC2
Number of Residues	8
Details	binding site for residue EDO A 202

Chain	Residue
A	SER151
A	TRP152
A	HOH308
A	HOH310
A	HOH373
A	ALA34
A	ASN36
A	GLN150

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site_id	AC3
Number of Residues	4
Details	binding site for residue EDO A 203

Chain	Residue
A	TYR9
A	GLY63
A	GLU87
A	HOH317

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site_id	AC4
Number of Residues	6
Details	binding site for residue EDO A 204

Chain	Residue
A	THR53
A	GLU75
A	PRO77
A	LEU134
A	HOH337
A	HOH341

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site_id	AC5
Number of Residues	7
Details	binding site for residue EDO A 205

Chain	Residue
A	TYR21
A	VAL29
A	PRO128
A	GLN129
A	HOH307
A	HOH345
A	HOH361

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site_id	AC6
Number of Residues	5
Details	binding site for residue EDO A 206

Chain	Residue
A	LYS13
A	ALA19
A	GLY107
A	SER108
A	HOH302

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