5BMU

The crystal structure of the GST-like domains complex of AIMP3-EPRS mutant C92SC105SC123S

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0006418	biological_process	tRNA aminoacylation for protein translation
A	0008285	biological_process	negative regulation of cell population proliferation
A	0017101	cellular_component	aminoacyl-tRNA synthetase multienzyme complex
A	0043065	biological_process	positive regulation of apoptotic process
A	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator
A	2000774	biological_process	positive regulation of cellular senescence
B	0017101	cellular_component	aminoacyl-tRNA synthetase multienzyme complex
B	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006412	biological_process	translation
C	0006418	biological_process	tRNA aminoacylation for protein translation
C	0008285	biological_process	negative regulation of cell population proliferation
C	0017101	cellular_component	aminoacyl-tRNA synthetase multienzyme complex
C	0043065	biological_process	positive regulation of apoptotic process
C	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator
C	2000774	biological_process	positive regulation of cellular senescence
D	0017101	cellular_component	aminoacyl-tRNA synthetase multienzyme complex
D	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006412	biological_process	translation
E	0006418	biological_process	tRNA aminoacylation for protein translation
E	0008285	biological_process	negative regulation of cell population proliferation
E	0017101	cellular_component	aminoacyl-tRNA synthetase multienzyme complex
E	0043065	biological_process	positive regulation of apoptotic process
E	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator
E	2000774	biological_process	positive regulation of cellular senescence
F	0017101	cellular_component	aminoacyl-tRNA synthetase multienzyme complex
F	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006412	biological_process	translation
G	0006418	biological_process	tRNA aminoacylation for protein translation
G	0008285	biological_process	negative regulation of cell population proliferation
G	0017101	cellular_component	aminoacyl-tRNA synthetase multienzyme complex
G	0043065	biological_process	positive regulation of apoptotic process
G	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator
G	2000774	biological_process	positive regulation of cellular senescence
H	0017101	cellular_component	aminoacyl-tRNA synthetase multienzyme complex
H	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	216
Details	Region: {"description":"N-terminal"}

Chain

Residue

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site_id	SWS_FT_FI2
Number of Residues	24
Details	Region: {"description":"Linker"}

Chain

Residue

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"DEC-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Calvo F.","Lilla S.","von Kriegsheim A.","Lempens A.","Kolch W."]}}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	264
Details	Region: {"description":"C-terminal"}

Chain

Residue

Details

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