5BMU

The crystal structure of the GST-like domains complex of AIMP3-EPRS mutant C92SC105SC123S

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005730	cellular_component	nucleolus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0008285	biological_process	negative regulation of cell population proliferation
A	0017101	cellular_component	aminoacyl-tRNA synthetase multienzyme complex
A	0032991	cellular_component	protein-containing complex
A	0043065	biological_process	positive regulation of apoptotic process
A	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator
A	1990830	biological_process	cellular response to leukemia inhibitory factor
A	2000774	biological_process	positive regulation of cellular senescence
A	2001235	biological_process	positive regulation of apoptotic signaling pathway
B	0017101	cellular_component	aminoacyl-tRNA synthetase multienzyme complex
B	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005730	cellular_component	nucleolus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006412	biological_process	translation
C	0008285	biological_process	negative regulation of cell population proliferation
C	0017101	cellular_component	aminoacyl-tRNA synthetase multienzyme complex
C	0032991	cellular_component	protein-containing complex
C	0043065	biological_process	positive regulation of apoptotic process
C	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator
C	1990830	biological_process	cellular response to leukemia inhibitory factor
C	2000774	biological_process	positive regulation of cellular senescence
C	2001235	biological_process	positive regulation of apoptotic signaling pathway
D	0017101	cellular_component	aminoacyl-tRNA synthetase multienzyme complex
D	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005730	cellular_component	nucleolus
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006412	biological_process	translation
E	0008285	biological_process	negative regulation of cell population proliferation
E	0017101	cellular_component	aminoacyl-tRNA synthetase multienzyme complex
E	0032991	cellular_component	protein-containing complex
E	0043065	biological_process	positive regulation of apoptotic process
E	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator
E	1990830	biological_process	cellular response to leukemia inhibitory factor
E	2000774	biological_process	positive regulation of cellular senescence
E	2001235	biological_process	positive regulation of apoptotic signaling pathway
F	0017101	cellular_component	aminoacyl-tRNA synthetase multienzyme complex
F	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005730	cellular_component	nucleolus
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006412	biological_process	translation
G	0008285	biological_process	negative regulation of cell population proliferation
G	0017101	cellular_component	aminoacyl-tRNA synthetase multienzyme complex
G	0032991	cellular_component	protein-containing complex
G	0043065	biological_process	positive regulation of apoptotic process
G	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator
G	1990830	biological_process	cellular response to leukemia inhibitory factor
G	2000774	biological_process	positive regulation of cellular senescence
G	2001235	biological_process	positive regulation of apoptotic signaling pathway
H	0017101	cellular_component	aminoacyl-tRNA synthetase multienzyme complex
H	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: N-acetylalanine => ECO:0000269|Ref.6

Chain	Residue	Details
A	ALA2
C	ALA2
E	ALA2
G	ALA2

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site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS138
C	LYS138
E	LYS138
G	LYS138

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