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5B8B

Crystal structure of reduced chimeric E.coli AhpC1-186-YFSKHN

Functional Information from GO Data
ChainGOidnamespacecontents
A0004601molecular_functionperoxidase activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006979biological_processresponse to oxidative stress
A0008379molecular_functionthioredoxin peroxidase activity
A0009321cellular_componentalkyl hydroperoxide reductase complex
A0009970biological_processcellular response to sulfate starvation
A0016020cellular_componentmembrane
A0016209molecular_functionantioxidant activity
A0016491molecular_functionoxidoreductase activity
A0016684molecular_functionoxidoreductase activity, acting on peroxide as acceptor
A0019290biological_processsiderophore biosynthetic process
A0032843molecular_functionhydroperoxide reductase activity
A0033194biological_processresponse to hydroperoxide
A0033195biological_processresponse to alkyl hydroperoxide
A0033554biological_processcellular response to stress
A0042744biological_processhydrogen peroxide catabolic process
A0042802molecular_functionidentical protein binding
A0045454biological_processcell redox homeostasis
A0051920molecular_functionperoxiredoxin activity
A0098869biological_processcellular oxidant detoxification
A0102039molecular_functionNADH-dependent peroxiredoxin activity
B0004601molecular_functionperoxidase activity
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006979biological_processresponse to oxidative stress
B0008379molecular_functionthioredoxin peroxidase activity
B0009321cellular_componentalkyl hydroperoxide reductase complex
B0009970biological_processcellular response to sulfate starvation
B0016020cellular_componentmembrane
B0016209molecular_functionantioxidant activity
B0016491molecular_functionoxidoreductase activity
B0016684molecular_functionoxidoreductase activity, acting on peroxide as acceptor
B0019290biological_processsiderophore biosynthetic process
B0032843molecular_functionhydroperoxide reductase activity
B0033194biological_processresponse to hydroperoxide
B0033195biological_processresponse to alkyl hydroperoxide
B0033554biological_processcellular response to stress
B0042744biological_processhydrogen peroxide catabolic process
B0042802molecular_functionidentical protein binding
B0045454biological_processcell redox homeostasis
B0051920molecular_functionperoxiredoxin activity
B0098869biological_processcellular oxidant detoxification
B0102039molecular_functionNADH-dependent peroxiredoxin activity
C0004601molecular_functionperoxidase activity
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0006979biological_processresponse to oxidative stress
C0008379molecular_functionthioredoxin peroxidase activity
C0009321cellular_componentalkyl hydroperoxide reductase complex
C0009970biological_processcellular response to sulfate starvation
C0016020cellular_componentmembrane
C0016209molecular_functionantioxidant activity
C0016491molecular_functionoxidoreductase activity
C0016684molecular_functionoxidoreductase activity, acting on peroxide as acceptor
C0019290biological_processsiderophore biosynthetic process
C0032843molecular_functionhydroperoxide reductase activity
C0033194biological_processresponse to hydroperoxide
C0033195biological_processresponse to alkyl hydroperoxide
C0033554biological_processcellular response to stress
C0042744biological_processhydrogen peroxide catabolic process
C0042802molecular_functionidentical protein binding
C0045454biological_processcell redox homeostasis
C0051920molecular_functionperoxiredoxin activity
C0098869biological_processcellular oxidant detoxification
C0102039molecular_functionNADH-dependent peroxiredoxin activity
D0004601molecular_functionperoxidase activity
D0005515molecular_functionprotein binding
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0006979biological_processresponse to oxidative stress
D0008379molecular_functionthioredoxin peroxidase activity
D0009321cellular_componentalkyl hydroperoxide reductase complex
D0009970biological_processcellular response to sulfate starvation
D0016020cellular_componentmembrane
D0016209molecular_functionantioxidant activity
D0016491molecular_functionoxidoreductase activity
D0016684molecular_functionoxidoreductase activity, acting on peroxide as acceptor
D0019290biological_processsiderophore biosynthetic process
D0032843molecular_functionhydroperoxide reductase activity
D0033194biological_processresponse to hydroperoxide
D0033195biological_processresponse to alkyl hydroperoxide
D0033554biological_processcellular response to stress
D0042744biological_processhydrogen peroxide catabolic process
D0042802molecular_functionidentical protein binding
D0045454biological_processcell redox homeostasis
D0051920molecular_functionperoxiredoxin activity
D0098869biological_processcellular oxidant detoxification
D0102039molecular_functionNADH-dependent peroxiredoxin activity
E0004601molecular_functionperoxidase activity
E0005515molecular_functionprotein binding
E0005737cellular_componentcytoplasm
E0005829cellular_componentcytosol
E0006979biological_processresponse to oxidative stress
E0008379molecular_functionthioredoxin peroxidase activity
E0009321cellular_componentalkyl hydroperoxide reductase complex
E0009970biological_processcellular response to sulfate starvation
E0016020cellular_componentmembrane
E0016209molecular_functionantioxidant activity
E0016491molecular_functionoxidoreductase activity
E0016684molecular_functionoxidoreductase activity, acting on peroxide as acceptor
E0019290biological_processsiderophore biosynthetic process
E0032843molecular_functionhydroperoxide reductase activity
E0033194biological_processresponse to hydroperoxide
E0033195biological_processresponse to alkyl hydroperoxide
E0033554biological_processcellular response to stress
E0042744biological_processhydrogen peroxide catabolic process
E0042802molecular_functionidentical protein binding
E0045454biological_processcell redox homeostasis
E0051920molecular_functionperoxiredoxin activity
E0098869biological_processcellular oxidant detoxification
E0102039molecular_functionNADH-dependent peroxiredoxin activity
F0004601molecular_functionperoxidase activity
F0005515molecular_functionprotein binding
F0005737cellular_componentcytoplasm
F0005829cellular_componentcytosol
F0006979biological_processresponse to oxidative stress
F0008379molecular_functionthioredoxin peroxidase activity
F0009321cellular_componentalkyl hydroperoxide reductase complex
F0009970biological_processcellular response to sulfate starvation
F0016020cellular_componentmembrane
F0016209molecular_functionantioxidant activity
F0016491molecular_functionoxidoreductase activity
F0016684molecular_functionoxidoreductase activity, acting on peroxide as acceptor
F0019290biological_processsiderophore biosynthetic process
F0032843molecular_functionhydroperoxide reductase activity
F0033194biological_processresponse to hydroperoxide
F0033195biological_processresponse to alkyl hydroperoxide
F0033554biological_processcellular response to stress
F0042744biological_processhydrogen peroxide catabolic process
F0042802molecular_functionidentical protein binding
F0045454biological_processcell redox homeostasis
F0051920molecular_functionperoxiredoxin activity
F0098869biological_processcellular oxidant detoxification
F0102039molecular_functionNADH-dependent peroxiredoxin activity
G0004601molecular_functionperoxidase activity
G0005515molecular_functionprotein binding
G0005737cellular_componentcytoplasm
G0005829cellular_componentcytosol
G0006979biological_processresponse to oxidative stress
G0008379molecular_functionthioredoxin peroxidase activity
G0009321cellular_componentalkyl hydroperoxide reductase complex
G0009970biological_processcellular response to sulfate starvation
G0016020cellular_componentmembrane
G0016209molecular_functionantioxidant activity
G0016491molecular_functionoxidoreductase activity
G0016684molecular_functionoxidoreductase activity, acting on peroxide as acceptor
G0019290biological_processsiderophore biosynthetic process
G0032843molecular_functionhydroperoxide reductase activity
G0033194biological_processresponse to hydroperoxide
G0033195biological_processresponse to alkyl hydroperoxide
G0033554biological_processcellular response to stress
G0042744biological_processhydrogen peroxide catabolic process
G0042802molecular_functionidentical protein binding
G0045454biological_processcell redox homeostasis
G0051920molecular_functionperoxiredoxin activity
G0098869biological_processcellular oxidant detoxification
G0102039molecular_functionNADH-dependent peroxiredoxin activity
H0004601molecular_functionperoxidase activity
H0005515molecular_functionprotein binding
H0005737cellular_componentcytoplasm
H0005829cellular_componentcytosol
H0006979biological_processresponse to oxidative stress
H0008379molecular_functionthioredoxin peroxidase activity
H0009321cellular_componentalkyl hydroperoxide reductase complex
H0009970biological_processcellular response to sulfate starvation
H0016020cellular_componentmembrane
H0016209molecular_functionantioxidant activity
H0016491molecular_functionoxidoreductase activity
H0016684molecular_functionoxidoreductase activity, acting on peroxide as acceptor
H0019290biological_processsiderophore biosynthetic process
H0032843molecular_functionhydroperoxide reductase activity
H0033194biological_processresponse to hydroperoxide
H0033195biological_processresponse to alkyl hydroperoxide
H0033554biological_processcellular response to stress
H0042744biological_processhydrogen peroxide catabolic process
H0042802molecular_functionidentical protein binding
H0045454biological_processcell redox homeostasis
H0051920molecular_functionperoxiredoxin activity
H0098869biological_processcellular oxidant detoxification
H0102039molecular_functionNADH-dependent peroxiredoxin activity
I0004601molecular_functionperoxidase activity
I0005515molecular_functionprotein binding
I0005737cellular_componentcytoplasm
I0005829cellular_componentcytosol
I0006979biological_processresponse to oxidative stress
I0008379molecular_functionthioredoxin peroxidase activity
I0009321cellular_componentalkyl hydroperoxide reductase complex
I0009970biological_processcellular response to sulfate starvation
I0016020cellular_componentmembrane
I0016209molecular_functionantioxidant activity
I0016491molecular_functionoxidoreductase activity
I0016684molecular_functionoxidoreductase activity, acting on peroxide as acceptor
I0019290biological_processsiderophore biosynthetic process
I0032843molecular_functionhydroperoxide reductase activity
I0033194biological_processresponse to hydroperoxide
I0033195biological_processresponse to alkyl hydroperoxide
I0033554biological_processcellular response to stress
I0042744biological_processhydrogen peroxide catabolic process
I0042802molecular_functionidentical protein binding
I0045454biological_processcell redox homeostasis
I0051920molecular_functionperoxiredoxin activity
I0098869biological_processcellular oxidant detoxification
I0102039molecular_functionNADH-dependent peroxiredoxin activity
J0004601molecular_functionperoxidase activity
J0005515molecular_functionprotein binding
J0005737cellular_componentcytoplasm
J0005829cellular_componentcytosol
J0006979biological_processresponse to oxidative stress
J0008379molecular_functionthioredoxin peroxidase activity
J0009321cellular_componentalkyl hydroperoxide reductase complex
J0009970biological_processcellular response to sulfate starvation
J0016020cellular_componentmembrane
J0016209molecular_functionantioxidant activity
J0016491molecular_functionoxidoreductase activity
J0016684molecular_functionoxidoreductase activity, acting on peroxide as acceptor
J0019290biological_processsiderophore biosynthetic process
J0032843molecular_functionhydroperoxide reductase activity
J0033194biological_processresponse to hydroperoxide
J0033195biological_processresponse to alkyl hydroperoxide
J0033554biological_processcellular response to stress
J0042744biological_processhydrogen peroxide catabolic process
J0042802molecular_functionidentical protein binding
J0045454biological_processcell redox homeostasis
J0051920molecular_functionperoxiredoxin activity
J0098869biological_processcellular oxidant detoxification
J0102039molecular_functionNADH-dependent peroxiredoxin activity
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue SO4 A 201
ChainResidue
APRO48
ASER86
AGLU87
ATHR88

site_idAC2
Number of Residues3
Detailsbinding site for residue SO4 C 201
ChainResidue
CILE22
CGLU23
CASP28

site_idAC3
Number of Residues4
Detailsbinding site for residue SO4 D 201
ChainResidue
DGLU139
EPHE77
DARG112
DGLU115

site_idAC4
Number of Residues3
Detailsbinding site for residue SO4 D 202
ChainResidue
DPRO10
DGLU26
DLYS27

site_idAC5
Number of Residues3
Detailsbinding site for residue SO4 E 201
ChainResidue
ESER86
EGLU87
ETHR88

site_idAC6
Number of Residues1
Detailsbinding site for residue SO4 E 202
ChainResidue
ELYS153

site_idAC7
Number of Residues4
Detailsbinding site for residue SO4 E 203
ChainResidue
EASP144
FSER146
FASP147
FARG150

site_idAC8
Number of Residues2
Detailsbinding site for residue SO4 E 204
ChainResidue
ETHR6
ELYS7

site_idAC9
Number of Residues2
Detailsbinding site for residue SO4 E 205
ChainResidue
ELYS17
ETYR69

site_idAD1
Number of Residues4
Detailsbinding site for residue SO4 G 201
ChainResidue
GGLY19
GGLU20
GPHE21
GLYS80

site_idAD2
Number of Residues1
Detailsbinding site for residue SO4 G 202
ChainResidue
GGLU30

site_idAD3
Number of Residues3
Detailsbinding site for residue SO4 G 203
ChainResidue
FPHE77
GPRO40
GGLU139

site_idAD4
Number of Residues3
Detailsbinding site for residue SO4 G 204
ChainResidue
GSER86
GGLU87
GTHR88

site_idAD5
Number of Residues4
Detailsbinding site for residue SO4 H 201
ChainResidue
HARG112
HLEU117
HGLU139
IPHE77

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues10
DetailsACT_SITE: Cysteine sulfenic acid (-SOH) intermediate => ECO:0000305|PubMed:27892488
ChainResidueDetails
ACYS47
HCYS47
BCYS47
ICYS47
JCYS47
CCYS47
DCYS47
FCYS47
ECYS47
GCYS47

site_idSWS_FT_FI2
Number of Residues50
DetailsMOD_RES: N6-acetyllysine => ECO:0000269|PubMed:18723842
ChainResidueDetails
ALYS17
BLYS171
ILYS17
ILYS93
ILYS153
ILYS169
ILYS171
JLYS17
JLYS93
JLYS153
JLYS169
ALYS93
JLYS171
CLYS17
CLYS93
CLYS153
CLYS169
CLYS171
DLYS17
DLYS93
DLYS153
DLYS169
ALYS153
DLYS171
FLYS17
FLYS93
FLYS153
FLYS169
FLYS171
ELYS17
ELYS93
ELYS153
ELYS169
ALYS169
ELYS171
GLYS17
GLYS93
GLYS153
GLYS169
GLYS171
HLYS17
HLYS93
HLYS153
HLYS169
ALYS171
HLYS171
BLYS17
BLYS93
BLYS153
BLYS169

226707

PDB entries from 2024-10-30

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