5B55
Crystal structure of hydrogen sulfide-producing enzyme (Fn1055) D232N mutant in complexed with alpha-aminoacrylate intermediate: lysine-dimethylated form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004124 | molecular_function | cysteine synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006535 | biological_process | L-cysteine biosynthetic process from L-serine |
| A | 0016740 | molecular_function | transferase activity |
| A | 0080146 | molecular_function | L-cysteine desulfhydrase activity |
| A | 1901605 | biological_process | alpha-amino acid metabolic process |
| B | 0004124 | molecular_function | cysteine synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006535 | biological_process | L-cysteine biosynthetic process from L-serine |
| B | 0016740 | molecular_function | transferase activity |
| B | 0080146 | molecular_function | L-cysteine desulfhydrase activity |
| B | 1901605 | biological_process | alpha-amino acid metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue PLP A 401 |
| Chain | Residue |
| A | LYS46 |
| A | GLY229 |
| A | ILE230 |
| A | SER272 |
| A | ASP299 |
| A | TYR304 |
| A | 0JO402 |
| A | HOH518 |
| A | HOH523 |
| A | HOH536 |
| A | HOH577 |
| A | ASN76 |
| A | GLY182 |
| A | GLY184 |
| A | THR185 |
| A | GLY186 |
| A | GLY187 |
| A | THR188 |
| A | GLU228 |
| site_id | AC2 |
| Number of Residues | 24 |
| Details | binding site for residue 0JO A 402 |
| Chain | Residue |
| A | LYS46 |
| A | THR73 |
| A | SER74 |
| A | ASN76 |
| A | THR77 |
| A | GLN147 |
| A | GLY182 |
| A | VAL183 |
| A | GLY184 |
| A | THR185 |
| A | GLY186 |
| A | GLY187 |
| A | THR188 |
| A | GLY229 |
| A | ILE230 |
| A | ASN232 |
| A | SER272 |
| A | PRO298 |
| A | ASP299 |
| A | TYR304 |
| A | PLP401 |
| A | HOH518 |
| A | HOH536 |
| A | HOH577 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue PEG A 403 |
| Chain | Residue |
| A | MLY327 |
| A | GLU328 |
| B | MLY5 |
| B | ALA86 |
| B | ILE87 |
| site_id | AC4 |
| Number of Residues | 24 |
| Details | binding site for residue 0JO B 402 |
| Chain | Residue |
| B | LYS46 |
| B | THR73 |
| B | SER74 |
| B | ASN76 |
| B | THR77 |
| B | GLN147 |
| B | GLY182 |
| B | VAL183 |
| B | GLY184 |
| B | THR185 |
| B | GLY186 |
| B | GLY187 |
| B | THR188 |
| B | GLY229 |
| B | ILE230 |
| B | SER272 |
| B | PRO298 |
| B | ASP299 |
| B | TYR304 |
| B | PLP401 |
| B | HOH516 |
| B | HOH518 |
| B | HOH525 |
| B | HOH571 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue PEG B 403 |
| Chain | Residue |
| B | GLU10 |
| B | MLY15 |
| B | TYR159 |
| B | GLY160 |
| B | GLU164 |
| B | HOH537 |
| B | HOH562 |
| B | HOH603 |
| site_id | AC6 |
| Number of Residues | 27 |
| Details | binding site for Di-peptide PLP B 401 and LYS B 46 |
| Chain | Residue |
| B | ASP299 |
| B | TYR304 |
| B | 0JO402 |
| B | HOH516 |
| B | HOH518 |
| B | HOH525 |
| B | HOH552 |
| B | HOH571 |
| B | SER44 |
| B | ILE45 |
| B | ASP47 |
| B | ARG48 |
| B | MET49 |
| B | ALA50 |
| B | ASN76 |
| B | THR77 |
| B | ALA80 |
| B | GLY182 |
| B | GLY184 |
| B | THR185 |
| B | GLY186 |
| B | GLY187 |
| B | THR188 |
| B | GLU228 |
| B | GLY229 |
| B | ILE230 |
| B | SER272 |
