Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003677 | molecular_function | DNA binding |
A | 0003723 | molecular_function | RNA binding |
A | 0004519 | molecular_function | endonuclease activity |
A | 0046872 | molecular_function | metal ion binding |
A | 0051607 | biological_process | defense response to virus |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue ZN A 1701 |
Chain | Residue |
A | CYS460 |
A | CYS657 |
A | CYS814 |
A | CYS817 |
site_id | AC2 |
Number of Residues | 6 |
Details | binding site for residue NA A 1702 |
Chain | Residue |
A | HOH2368 |
A | PHE647 |
A | ASP649 |
A | HOH2031 |
A | HOH2189 |
A | HOH2251 |
site_id | AC3 |
Number of Residues | 6 |
Details | binding site for residue NA A 1703 |
Chain | Residue |
A | HOH2374 |
B | HOH232 |
B | HOH301 |
B | HOH442 |
B | HOH529 |
B | HOH537 |
site_id | AC4 |
Number of Residues | 3 |
Details | binding site for residue CL A 1704 |
Chain | Residue |
A | LYS564 |
A | PHE602 |
A | HOH2268 |
site_id | AC5 |
Number of Residues | 5 |
Details | binding site for residue CL A 1705 |
Chain | Residue |
A | LYS366 |
A | LYS370 |
A | TRP395 |
A | GLU399 |
A | HOH2015 |
site_id | AC6 |
Number of Residues | 5 |
Details | binding site for residue CA A 1706 |
Chain | Residue |
A | ASP11 |
A | GLU903 |
A | HIS1162 |
A | HOH1839 |
A | HOH1883 |
site_id | AC7 |
Number of Residues | 7 |
Details | binding site for residue CA A 1707 |
Chain | Residue |
A | ASP66 |
A | HOH2357 |
B | A60 |
B | HOH317 |
B | HOH322 |
B | HOH408 |
B | HOH503 |
site_id | AC8 |
Number of Residues | 7 |
Details | binding site for residue CA A 1708 |
Chain | Residue |
A | HOH1808 |
A | HOH1984 |
A | HOH2401 |
A | HOH2409 |
C | HOH210 |
C | HOH229 |
C | HOH264 |
site_id | AC9 |
Number of Residues | 8 |
Details | binding site for residue CA A 1709 |
Chain | Residue |
A | ASP66 |
A | HOH1818 |
B | HOH284 |
B | HOH303 |
B | HOH338 |
B | HOH377 |
B | HOH408 |
B | HOH525 |
site_id | AD1 |
Number of Residues | 6 |
Details | binding site for residue CA A 1710 |
Chain | Residue |
A | VAL402 |
A | HOH2319 |
A | HOH2358 |
B | U83 |
B | HOH490 |
B | HOH499 |
site_id | AD2 |
Number of Residues | 6 |
Details | binding site for residue CA A 1711 |
Chain | Residue |
A | HOH1880 |
A | HOH1893 |
A | HOH2439 |
B | HOH296 |
B | HOH325 |
B | HOH496 |
site_id | AD3 |
Number of Residues | 5 |
Details | binding site for residue CA A 1712 |
Chain | Residue |
A | SER507 |
A | HOH2367 |
A | HOH2369 |
B | HOH278 |
B | HOH423 |
site_id | AD4 |
Number of Residues | 5 |
Details | binding site for residue CA A 1713 |
Chain | Residue |
A | LYS1415 |
A | ASP1417 |
A | HOH2141 |
A | HOH2379 |
A | HOH2386 |
site_id | AD5 |
Number of Residues | 7 |
Details | binding site for residue CA A 1714 |
Chain | Residue |
A | HOH1846 |
A | HOH2045 |
A | HOH2078 |
A | HOH2195 |
B | HOH250 |
C | HOH204 |
C | HOH258 |
site_id | AD6 |
Number of Residues | 4 |
Details | binding site for residue CA A 1715 |
Chain | Residue |
A | GLU1231 |
A | ASN1234 |
A | ASP1498 |
A | SER1499 |
site_id | AD7 |
Number of Residues | 7 |
Details | binding site for residue CA A 1716 |
Chain | Residue |
A | HOH2160 |
A | HOH2293 |
A | HOH2332 |
B | HOH283 |
B | HOH345 |
B | HOH481 |
B | HOH516 |
site_id | AD8 |
Number of Residues | 6 |
Details | binding site for residue EDO A 1717 |
Chain | Residue |
A | LYS45 |
A | TYR48 |
A | THR49 |
A | LEU50 |
A | LEU51 |
A | VAL911 |
site_id | AD9 |
Number of Residues | 7 |
Details | binding site for residue EDO A 1718 |
Chain | Residue |
A | TYR332 |
A | ASN335 |
A | PHE336 |
A | TYR345 |
A | HOH1951 |
A | ASP90 |
A | THR91 |
site_id | AE1 |
Number of Residues | 6 |
Details | binding site for residue EDO A 1719 |
Chain | Residue |
A | HIS394 |
A | LEU397 |
A | GLY398 |
A | HOH1902 |
A | HOH1942 |
A | HOH2135 |
site_id | AE2 |
Number of Residues | 8 |
Details | binding site for residue EDO A 1720 |
Chain | Residue |
A | LEU626 |
A | TYR627 |
A | ILE628 |
A | TYR656 |
A | ARG1093 |
A | GLU1097 |
A | HOH2090 |
A | HOH2136 |
site_id | AE3 |
Number of Residues | 6 |
Details | binding site for residue EDO A 1721 |
Chain | Residue |
A | ARG625 |
A | TYR627 |
A | SER1118 |
A | PHE1119 |
A | HOH1863 |
A | HOH2101 |
site_id | AE4 |
Number of Residues | 6 |
Details | binding site for residue EDO A 1722 |
Chain | Residue |
A | LYS459 |
A | GLY645 |
A | PHE647 |
A | ASN658 |
A | HOH1835 |
A | HOH2274 |
site_id | AE5 |
Number of Residues | 7 |
Details | binding site for residue EDO A 1723 |
Chain | Residue |
A | PRO1251 |
A | TYR1265 |
A | TYR1329 |
A | HOH1805 |
A | HOH2085 |
B | EDO109 |
B | EDO115 |
site_id | AE6 |
Number of Residues | 7 |
Details | binding site for residue EDO A 1724 |
Chain | Residue |
A | SER105 |
A | ILE107 |
A | ASP406 |
A | PRO447 |
A | PRO448 |
A | HOH1971 |
A | HOH2077 |
site_id | AE7 |
Number of Residues | 4 |
Details | binding site for residue EDO A 1725 |
Chain | Residue |
A | GLN478 |
A | TYR530 |
A | LYS531 |
A | ASP534 |
site_id | AE8 |
Number of Residues | 7 |
Details | binding site for residue EDO A 1726 |
Chain | Residue |
A | LEU6 |
A | SER21 |
A | ALA22 |
A | PHE23 |
A | ASN37 |
A | ASN877 |
A | ASN880 |
site_id | AE9 |
Number of Residues | 4 |
Details | binding site for residue EDO A 1727 |
Chain | Residue |
A | SER899 |
A | ALA901 |
A | PHE904 |
A | ASN1089 |
site_id | AF1 |
Number of Residues | 8 |
Details | binding site for residue ACT A 1728 |
Chain | Residue |
A | GLN92 |
A | THR1458 |
A | TRP1459 |
A | ASP1460 |
A | ASN1462 |
A | HOH1974 |
A | HOH2222 |
B | A50 |
site_id | AF2 |
Number of Residues | 7 |
Details | binding site for residue NA B 101 |
Chain | Residue |
B | G28 |
B | U30 |
B | U45 |
B | NA102 |
B | HOH288 |
B | HOH510 |
B | HOH519 |
site_id | AF3 |
Number of Residues | 8 |
Details | binding site for residue NA B 102 |
Chain | Residue |
B | U45 |
B | NA101 |
B | HOH262 |
B | HOH475 |
B | HOH510 |
B | HOH514 |
B | HOH539 |
B | HOH541 |
site_id | AF4 |
Number of Residues | 7 |
Details | binding site for residue CA B 103 |
Chain | Residue |
B | HOH204 |
B | HOH214 |
B | HOH237 |
B | HOH277 |
B | HOH280 |
B | HOH313 |
B | HOH500 |
site_id | AF5 |
Number of Residues | 7 |
Details | binding site for residue CA B 104 |
Chain | Residue |
A | HOH2381 |
A | HOH2419 |
B | U93 |
B | HOH224 |
B | HOH416 |
B | HOH430 |
B | HOH534 |
site_id | AF6 |
Number of Residues | 6 |
Details | binding site for residue CA B 105 |
Chain | Residue |
B | G74 |
B | HOH268 |
B | HOH354 |
B | HOH362 |
B | HOH444 |
B | HOH506 |
site_id | AF7 |
Number of Residues | 6 |
Details | binding site for residue CA B 106 |
Chain | Residue |
A | HOH1824 |
B | HOH230 |
B | HOH258 |
B | HOH269 |
B | HOH428 |
B | HOH536 |
site_id | AF8 |
Number of Residues | 8 |
Details | binding site for residue CA B 107 |
Chain | Residue |
A | HOH2398 |
B | G20 |
B | HOH243 |
B | HOH246 |
B | HOH312 |
B | HOH395 |
B | HOH533 |
B | HOH535 |
site_id | AF9 |
Number of Residues | 5 |
Details | binding site for residue CA B 108 |
Chain | Residue |
B | U12 |
B | G13 |
B | HOH205 |
B | HOH472 |
C | HOH224 |
site_id | AG1 |
Number of Residues | 6 |
Details | binding site for residue EDO B 109 |
Chain | Residue |
A | TYR1265 |
A | EDO1723 |
B | C42 |
B | G43 |
B | HOH233 |
B | HOH257 |
site_id | AG2 |
Number of Residues | 6 |
Details | binding site for residue EDO B 110 |
Chain | Residue |
A | ARG1404 |
A | HOH2112 |
B | G31 |
B | C44 |
B | U45 |
B | HOH211 |
site_id | AG3 |
Number of Residues | 5 |
Details | binding site for residue EDO B 111 |
Chain | Residue |
A | ARG59 |
A | ARG62 |
B | A61 |
B | G62 |
B | HOH317 |
site_id | AG4 |
Number of Residues | 6 |
Details | binding site for residue EDO B 112 |
Chain | Residue |
A | SER105 |
A | TYR449 |
B | U17 |
B | HOH248 |
B | HOH302 |
B | HOH350 |
site_id | AG5 |
Number of Residues | 7 |
Details | binding site for residue EDO B 113 |
Chain | Residue |
A | GLY309 |
B | G19 |
B | G20 |
B | HOH215 |
B | HOH221 |
B | HOH227 |
C | HOH218 |
site_id | AG6 |
Number of Residues | 7 |
Details | binding site for residue EDO B 114 |
Chain | Residue |
A | ARG369 |
B | G73 |
B | C89 |
B | HOH222 |
B | HOH293 |
B | HOH352 |
B | HOH403 |
site_id | AG7 |
Number of Residues | 6 |
Details | binding site for residue EDO B 115 |
Chain | Residue |
A | TYR1329 |
A | EDO1723 |
B | C34 |
B | C35 |
B | G41 |
B | HOH257 |
site_id | AG8 |
Number of Residues | 7 |
Details | binding site for residue EDO B 116 |
Chain | Residue |
A | MET52 |
A | ARG55 |
A | LYS864 |
A | HOH2317 |
B | A64 |
B | G69 |
B | HOH279 |
site_id | AG9 |
Number of Residues | 7 |
Details | binding site for residue EDO B 117 |
Chain | Residue |
A | ARG455 |
A | LYS456 |
B | A71 |
B | C72 |
B | C89 |
B | HOH222 |
B | HOH280 |
site_id | AH1 |
Number of Residues | 3 |
Details | binding site for residue EDO B 118 |
Chain | Residue |
B | A71 |
B | G94 |
B | HOH201 |
site_id | AH2 |
Number of Residues | 6 |
Details | binding site for residue EDO B 119 |
Chain | Residue |
B | C32 |
B | G33 |
B | C34 |
B | HOH297 |
B | HOH413 |
B | HOH464 |
site_id | AH3 |
Number of Residues | 8 |
Details | binding site for residue ACT B 120 |
Chain | Residue |
A | ASN1248 |
A | SER1368 |
A | ARG1370 |
A | PHE1398 |
B | C44 |
B | HOH232 |
B | HOH247 |
B | HOH281 |
site_id | AH4 |
Number of Residues | 5 |
Details | binding site for residue EDO C 101 |
Chain | Residue |
A | ASN1089 |
A | GLY1090 |
C | DC21 |
C | DT22 |
C | HOH208 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP11 | |
Chain | Residue | Details |
A | ALA995 | |
Chain | Residue | Details |
A | ASP11 | |
A | ASP876 | |
A | ASN880 | |
A | HIS1162 | |
Chain | Residue | Details |
A | CYS460 | |
A | CYS657 | |
A | CYS814 | |
A | CYS817 | |
Chain | Residue | Details |
A | ARG1556 | |
A | ARG1585 | |