5B1H
Crystal structure of cystathionine beta-synthase from Lactobacillus plantarum
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004124 | molecular_function | cysteine synthase activity |
| A | 0006535 | biological_process | cysteine biosynthetic process from serine |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019344 | biological_process | cysteine biosynthetic process |
| B | 0004124 | molecular_function | cysteine synthase activity |
| B | 0006535 | biological_process | cysteine biosynthetic process from serine |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019344 | biological_process | cysteine biosynthetic process |
| C | 0004124 | molecular_function | cysteine synthase activity |
| C | 0006535 | biological_process | cysteine biosynthetic process from serine |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| C | 0016829 | molecular_function | lyase activity |
| C | 0019344 | biological_process | cysteine biosynthetic process |
| D | 0004124 | molecular_function | cysteine synthase activity |
| D | 0006535 | biological_process | cysteine biosynthetic process from serine |
| D | 0008652 | biological_process | amino acid biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| D | 0016829 | molecular_function | lyase activity |
| D | 0019344 | biological_process | cysteine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 401 |
| Chain | Residue |
| A | ARG250 |
| A | HIS251 |
| A | ARG254 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | SER135 |
| A | ASN136 |
| A | SO4403 |
| A | HOH529 |
| D | LYS62 |
| D | ASN136 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 403 |
| Chain | Residue |
| A | LYS62 |
| A | ASN136 |
| A | SO4402 |
| A | HOH525 |
| A | HOH530 |
| D | SER135 |
| D | ASN136 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 404 |
| Chain | Residue |
| A | THR69 |
| A | ALA70 |
| A | GLY71 |
| A | ASN72 |
| A | THR73 |
| A | GLN142 |
| A | HOH544 |
| A | HOH548 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 405 |
| Chain | Residue |
| A | MET1 |
| C | MET1 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 406 |
| Chain | Residue |
| A | HIS5 |
| A | GLN7 |
| A | GLN82 |
| A | ALA83 |
| B | HIS25 |
| B | ASN281 |
| C | PRO19 |
| C | ASP255 |
| C | HIS256 |
| C | HOH505 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 407 |
| Chain | Residue |
| A | LEU54 |
| A | HIS84 |
| A | HOH531 |
| B | ASN24 |
| B | THR276 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 408 |
| Chain | Residue |
| A | THR169 |
| A | ALA280 |
| A | ASN281 |
| A | SER282 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 401 |
| Chain | Residue |
| B | ARG250 |
| B | HIS251 |
| B | ARG254 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 402 |
| Chain | Residue |
| B | THR69 |
| B | ALA70 |
| B | GLY71 |
| B | ASN72 |
| B | THR73 |
| B | GLN142 |
| B | HOH554 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 403 |
| Chain | Residue |
| A | HIS85 |
| B | ILE20 |
| B | GLU21 |
| B | VAL22 |
| B | HIS25 |
| B | HOH514 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 404 |
| Chain | Residue |
| B | ARG56 |
| B | ARG58 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 405 |
| Chain | Residue |
| B | HIS85 |
| B | ARG254 |
| B | HOH561 |
| C | ALA132 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 406 |
| Chain | Residue |
| B | THR169 |
| B | PRO279 |
| B | ALA280 |
| B | SER282 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 401 |
| Chain | Residue |
| C | ARG250 |
| C | HIS251 |
| C | ARG254 |
| site_id | AD7 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 C 402 |
| Chain | Residue |
| C | THR69 |
| C | ALA70 |
| C | GLY71 |
| C | ASN72 |
| C | THR73 |
| C | GLN142 |
| C | HOH535 |
| C | HOH541 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 C 403 |
| Chain | Residue |
| B | SER135 |
| B | ASN136 |
| C | LYS62 |
| C | ASN136 |
| C | SO4404 |
| C | HOH526 |
| C | HOH539 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 C 404 |
| Chain | Residue |
| B | LYS62 |
| B | ASN136 |
| C | SER135 |
| C | ASN136 |
| C | SO4403 |
| C | HOH536 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 405 |
| Chain | Residue |
| C | HIS154 |
| C | THR155 |
| C | GLU159 |
| C | HOH530 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 406 |
| Chain | Residue |
| C | LEU54 |
| C | ALA61 |
| C | HIS84 |
| C | HOH556 |
| D | ASN24 |
| D | THR276 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 407 |
| Chain | Residue |
| C | THR169 |
| C | ALA280 |
| C | ASN281 |
| C | SER282 |
| site_id | AE4 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 D 401 |
| Chain | Residue |
| D | THR69 |
| D | ALA70 |
| D | GLY71 |
| D | ASN72 |
| D | THR73 |
| D | GLN142 |
| D | HOH514 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 402 |
| Chain | Residue |
| D | ARG250 |
| D | HIS251 |
| D | ARG254 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 403 |
| Chain | Residue |
| C | HIS85 |
| D | ILE20 |
| D | GLU21 |
| D | VAL22 |
| D | HIS25 |
| D | HOH512 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 404 |
| Chain | Residue |
| A | PRO165 |
| A | HIS283 |
| D | LEU2 |
| D | GLN4 |
| D | GLU8 |
| site_id | AE8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 405 |
| Chain | Residue |
| D | THR169 |
| D | PRO279 |
| D | ALA280 |
| D | SER282 |
| D | HOH518 |
| D | HOH548 |
Functional Information from PROSITE/UniProt
| site_id | PS00901 |
| Number of Residues | 19 |
| Details | CYS_SYNTHASE Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. KlEmfn.PGgSIKdRlGayL |
| Chain | Residue | Details |
| A | LYS31-LEU49 |
