5AZJ

Crystal structure of glycerol kinase from Trypanosoma brucei gambiense complexed with 4NP (with disulfide bridge)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004370	molecular_function	glycerol kinase activity
A	0005524	molecular_function	ATP binding
A	0005739	cellular_component	mitochondrion
A	0005975	biological_process	carbohydrate metabolic process
A	0006071	biological_process	glycerol metabolic process
A	0006072	biological_process	glycerol-3-phosphate metabolic process
A	0006641	biological_process	triglyceride metabolic process
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
A	0019563	biological_process	glycerol catabolic process
A	0046167	biological_process	glycerol-3-phosphate biosynthetic process
B	0004370	molecular_function	glycerol kinase activity
B	0005524	molecular_function	ATP binding
B	0005739	cellular_component	mitochondrion
B	0005975	biological_process	carbohydrate metabolic process
B	0006071	biological_process	glycerol metabolic process
B	0006072	biological_process	glycerol-3-phosphate metabolic process
B	0006641	biological_process	triglyceride metabolic process
B	0016301	molecular_function	kinase activity
B	0016310	biological_process	phosphorylation
B	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
B	0019563	biological_process	glycerol catabolic process
B	0046167	biological_process	glycerol-3-phosphate biosynthetic process
C	0004370	molecular_function	glycerol kinase activity
C	0005524	molecular_function	ATP binding
C	0005739	cellular_component	mitochondrion
C	0005975	biological_process	carbohydrate metabolic process
C	0006071	biological_process	glycerol metabolic process
C	0006072	biological_process	glycerol-3-phosphate metabolic process
C	0006641	biological_process	triglyceride metabolic process
C	0016301	molecular_function	kinase activity
C	0016310	biological_process	phosphorylation
C	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
C	0019563	biological_process	glycerol catabolic process
C	0046167	biological_process	glycerol-3-phosphate biosynthetic process
D	0004370	molecular_function	glycerol kinase activity
D	0005524	molecular_function	ATP binding
D	0005739	cellular_component	mitochondrion
D	0005975	biological_process	carbohydrate metabolic process
D	0006071	biological_process	glycerol metabolic process
D	0006072	biological_process	glycerol-3-phosphate metabolic process
D	0006641	biological_process	triglyceride metabolic process
D	0016301	molecular_function	kinase activity
D	0016310	biological_process	phosphorylation
D	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
D	0019563	biological_process	glycerol catabolic process
D	0046167	biological_process	glycerol-3-phosphate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue 4NP A 601

Chain	Residue
A	THR11
A	THR12
A	GLY277
A	HOH717

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site_id	AC2
Number of Residues	6
Details	binding site for residue GOL A 602

Chain	Residue
A	HOH705
A	ARG84
A	GLU85
A	TRP104
A	ASP254
A	GLN255

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site_id	AC3
Number of Residues	6
Details	binding site for residue GOL B 601

Chain	Residue
B	ARG84
B	GLU85
B	TRP104
B	ASP254
B	GLN255
B	PHE279

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site_id	AC4
Number of Residues	3
Details	binding site for residue 4NP C 601

Chain	Residue
C	THR11
C	THR12
C	GLY277

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site_id	AC5
Number of Residues	4
Details	binding site for residue GOL C 602

Chain	Residue
C	ARG84
C	GLU85
C	ASP254
C	GLN255

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site_id	AC6
Number of Residues	6
Details	binding site for residue GOL D 601

Chain	Residue
D	ARG84
D	GLU85
D	TRP104
D	ASP254
D	GLN255
D	HOH717

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Functional Information from PROSITE/UniProt

site_id	PS00445
Number of Residues	21
Details	FGGY_KINASES_2 FGGY family of carbohydrate kinases signature 2. GtIVGMtlkttra.HVIRAALQ

Chain	Residue	Details
A	GLY373-GLN393
B	GLY373-GLN393

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