5AZC

Crystal structure of Escherichia coli Lgt in complex with phosphatidylglycerol

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0008961	molecular_function	phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity
A	0009898	cellular_component	cytoplasmic side of plasma membrane
A	0016740	molecular_function	transferase activity
A	0042158	biological_process	lipoprotein biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue PGT A 301

Chain	Residue
A	SER123
A	PGT310
A	PHE124
A	PHE125
A	ASN159
A	PHE160
A	PRO161
A	TYR201
A	LEU204
A	PHE245

---

site_id	AC2
Number of Residues	2
Details	binding site for residue PGT A 302

Chain	Residue
A	MET29
A	GLY207

---

site_id	AC3
Number of Residues	2
Details	binding site for residue PGT A 303

Chain	Residue
A	TYR282
A	PGT308

---

site_id	AC4
Number of Residues	3
Details	binding site for residue PGT A 304

Chain	Residue
A	ASN59
A	GLY71
A	VAL112

---

site_id	AC5
Number of Residues	2
Details	binding site for residue PGT A 305

Chain	Residue
A	PHE36
A	ARG47

---

site_id	AC6
Number of Residues	5
Details	binding site for residue PGT A 307

Chain	Residue
A	GLU10
A	PHE11
A	ASP12
A	TRP25
A	MET29

---

site_id	AC7
Number of Residues	5
Details	binding site for residue PGT A 308

Chain	Residue
A	TYR217
A	ARG222
A	PHE238
A	TYR282
A	PGT303

---

site_id	AC8
Number of Residues	16
Details	binding site for residue PGT A 309

Chain	Residue
A	TYR26
A	TYR30
A	PHE34
A	PHE69
A	VAL95
A	TRP96
A	GLY99
A	MET100
A	GLY138
A	ASN149
A	GLU151
A	GLY254
A	ALA255
A	TRP256
A	VAL257
A	HOH426

---

site_id	AC9
Number of Residues	12
Details	binding site for residue PGT A 310

Chain	Residue
A	TYR30
A	PHE102
A	LEU139
A	GLY142
A	ARG143
A	LEU204
A	TYR235
A	TYR259
A	PRO269
A	MET270
A	ALA273
A	PGT301

---

Functional Information from PROSITE/UniProt

site_id	PS01311
Number of Residues	13
Details	LGT Prolipoprotein diacylglyceryl transferase signature. GRlGNFINgElwG

Chain	Residue	Details
A	GLY142-GLY154

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	135
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"26729647","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5AZB","evidenceCode":"ECO:0000312"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	27
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"26729647","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22287519","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	83
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"26729647","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22287519","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01147","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"26729647","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---