5AZB
Crystal structure of Escherichia coli Lgt in complex with phosphatidylglycerol and the inhibitor palmitic acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008961 | molecular_function | phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity |
| A | 0009898 | cellular_component | cytoplasmic side of plasma membrane |
| A | 0016740 | molecular_function | transferase activity |
| A | 0042158 | biological_process | lipoprotein biosynthetic process |
Functional Information from PROSITE/UniProt
| site_id | PS01311 |
| Number of Residues | 13 |
| Details | LGT Prolipoprotein diacylglyceryl transferase signature. GRlGNFINgElwG |
| Chain | Residue | Details |
| A | GLY142-GLY154 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 135 |
| Details | TRANSMEM: Helical => ECO:0000269|PubMed:26729647, ECO:0000312|PDB:5AZB |
| Chain | Residue | Details |
| A | TRP25-ARG43 | |
| A | VAL57-TYR76 | |
| A | GLY99-ARG119 | |
| A | PHE130-GLY150 | |
| A | SER198-ILE218 | |
| A | ALA226-PHE244 | |
| A | MET262-TYR282 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 27 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:26729647, ECO:0000305|PubMed:22287519 |
| Chain | Residue | Details |
| A | ARG44-GLU56 | |
| A | THR120-ASP129 | |
| A | ARG219-GLY225 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 83 |
| Details | TOPO_DOM: Periplasmic => ECO:0000269|PubMed:26729647, ECO:0000305|PubMed:22287519 |
| Chain | Residue | Details |
| A | VAL77-GLY98 | |
| A | GLU151-PRO197 | |
| A | PHE245-SER261 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:26729647, ECO:0000305|PubMed:15919996, ECO:0000305|PubMed:22287519 |
| Chain | Residue | Details |
| A | ARG283-SER291 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01147, ECO:0000269|PubMed:26729647 |
| Chain | Residue | Details |
| A | ARG143 |
