Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1001 |
| Chain | Residue |
| A | ASP554 |
| A | HOH1104 |
| A | HOH1108 |
| A | HOH1159 |
| A | HOH1172 |
| A | HOH1178 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 1002 |
| Chain | Residue |
| A | ASP664 |
| A | HOH1108 |
| A | HOH1155 |
| A | HIS519 |
| A | HIS553 |
| A | ASP554 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue 4LK A 1003 |
| Chain | Residue |
| A | TYR514 |
| A | HIS515 |
| A | LEU625 |
| A | ALA626 |
| A | LEU665 |
| A | TYR683 |
| A | GLN716 |
| A | PHE719 |
| A | HOH1141 |
| A | HOH1163 |
| A | HOH1228 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1001 |
| Chain | Residue |
| B | ASP554 |
| B | HOH1109 |
| B | HOH1124 |
| B | HOH1149 |
| B | HOH1154 |
| B | HOH1171 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue ZN B 1002 |
| Chain | Residue |
| B | HIS519 |
| B | HIS553 |
| B | ASP554 |
| B | ASP664 |
| B | HOH1124 |
| B | HOH1138 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | binding site for residue 4LK B 1003 |
| Chain | Residue |
| A | LEU696 |
| A | GLY697 |
| A | ILE698 |
| B | TYR514 |
| B | LEU625 |
| B | ALA626 |
| B | PHE629 |
| B | LEU665 |
| B | ILE682 |
| B | TYR683 |
| B | GLN716 |
| B | PHE719 |
| B | HOH1132 |
| B | HOH1167 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHrGfsNsY |
| Chain | Residue | Details |
| A | HIS553-TYR564 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"O76083","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17389385","evidenceCode":"ECO:0000269"}]} |
