5ARL

crystal structure of porcine RNase 4 D80A mutant in complex with dCMP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
B	0003676	molecular_function	nucleic acid binding
C	0003676	molecular_function	nucleic acid binding
D	0003676	molecular_function	nucleic acid binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE DCM A 1120

Chain	Residue
A	HIS12
A	LYS40
A	PHE42
A	ASN43
A	THR44
A	HIS116
A	PHE117

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE DCM B 1120

Chain	Residue
B	LYS40
B	ASN43
B	THR44
B	HIS116
B	LYS119
C	LYS33
B	GLN11
B	HIS12

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE DCM C 1120

Chain	Residue
C	HIS12
C	PHE42
C	ASN43
C	THR44
C	PHE117
C	LYS119

---

site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE DCM D 1120

Chain	Residue
D	GLN11
D	HIS12
D	LYS40
D	PHE42
D	ASN43
D	THR44
D	HIS116
D	PHE117
D	LYS119

---

Functional Information from PROSITE/UniProt

site_id	PS00127
Number of Residues	7
Details	RNASE_PANCREATIC Pancreatic ribonuclease family signature. CKrfNTF

Chain	Residue	Details
A	CYS39-PHE45

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"Q9H1E1","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"Q9H1E1","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26748441","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5ARK","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Modified residue: {"description":"Pyrrolidone carboxylic acid","evidences":[{"source":"UniProtKB","id":"P15467","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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