5ARJ

crystal structure of porcine RNase 4 D80A mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
B	0003676	molecular_function	nucleic acid binding
C	0003676	molecular_function	nucleic acid binding
D	0003676	molecular_function	nucleic acid binding

Functional Information from PROSITE/UniProt

site_id	PS00127
Number of Residues	7
Details	RNASE_PANCREATIC Pancreatic ribonuclease family signature. CKrfNTF

Chain	Residue	Details
A	CYS39-PHE45

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:Q9H1E1

Chain	Residue	Details
A	HIS12
B	HIS12
C	HIS12
D	HIS12

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site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Proton donor => ECO:0000250|UniProtKB:Q9H1E1

Chain	Residue	Details
A	HIS116
B	HIS116
C	HIS116
D	HIS116

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site_id	SWS_FT_FI3
Number of Residues	24
Details	BINDING: BINDING => ECO:0000269|PubMed:26748441, ECO:0007744|PDB:5ARK

Chain	Residue	Details
A	ARG7
B	ASN43
B	THR44
B	PHE117
C	ARG7
C	HIS12
C	LYS40
C	ASN43
C	THR44
C	PHE117
D	ARG7
A	HIS12
D	HIS12
D	LYS40
D	ASN43
D	THR44
D	PHE117
A	LYS40
A	ASN43
A	THR44
A	PHE117
B	ARG7
B	HIS12
B	LYS40

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site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: Pyrrolidone carboxylic acid => ECO:0000250|UniProtKB:P15467

Chain	Residue	Details
A	GLN1
B	GLN1
C	GLN1
D	GLN1

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