5AMH

Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Thalidomide, trigonal crystal form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 150

Chain	Residue
A	CYS24
A	CYS27
A	CYS90
A	CYS93

---

site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE EF2 A 151

Chain	Residue
A	SER78
A	TRP79
A	TRP85
A	TRP99
A	TYR101
A	CL1128
A	HOH2079
A	GLY42
A	ASN50
A	PRO51
A	ARG68
A	PHE77

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 1126

Chain	Residue
A	ASP43
A	GLU45
A	LEU67
A	HOH2065
A	HOH2067
A	HOH2071

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 1127

Chain	Residue
A	ARG57
A	ASP116
A	HOH2089

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 1128

Chain	Residue
A	ARG68
A	HIS96
A	TRP99
A	EF2151

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 1129

Chain	Residue
A	HIS46
A	VAL47
A	GLY66

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 1130

Chain	Residue
A	SER20
A	ARG34
A	ASP35

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL A 1131

Chain	Residue
A	SER95
A	SER95
A	HIS96
A	HIS96
A	HOH2021
A	HOH2021

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL A 1132

Chain	Residue
A	VAL48
A	PHE49
A	GLN65
A	HOH2039
A	HOH2076
A	HOH2102

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 1133

Chain	Residue
A	HIS46
A	HOH2123

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NI A 1134

Chain	Residue
A	HIS44
A	HOH2068
A	HOH2069
A	HOH2070

---