5AJK

Crystal structure of variola virus virulence factor F1L in complex with human Bak BH3 domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0033668	biological_process	symbiont-mediated suppression of host apoptosis
A	0042981	biological_process	regulation of apoptotic process
B	0042981	biological_process	regulation of apoptotic process
C	0033668	biological_process	symbiont-mediated suppression of host apoptosis
C	0042981	biological_process	regulation of apoptotic process
D	0042981	biological_process	regulation of apoptotic process
E	0033668	biological_process	symbiont-mediated suppression of host apoptosis
E	0042981	biological_process	regulation of apoptotic process
F	0042981	biological_process	regulation of apoptotic process
G	0033668	biological_process	symbiont-mediated suppression of host apoptosis
G	0042981	biological_process	regulation of apoptotic process
H	0042981	biological_process	regulation of apoptotic process
I	0033668	biological_process	symbiont-mediated suppression of host apoptosis
I	0042981	biological_process	regulation of apoptotic process
J	0042981	biological_process	regulation of apoptotic process
K	0033668	biological_process	symbiont-mediated suppression of host apoptosis
K	0042981	biological_process	regulation of apoptotic process
L	0042981	biological_process	regulation of apoptotic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ACT C 1202

Chain	Residue
C	THR99
C	HOH2007

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT G 1201

Chain	Residue
G	PHE135
G	THR136
G	HOH2006

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ACT E 1202

Chain	Residue
E	PHE135

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 1202

Chain	Residue
A	LYS87
A	CL1203

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 1203

Chain	Residue
A	CL1202

---

Functional Information from PROSITE/UniProt

site_id	PS01259
Number of Residues	15
Details	BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VgrqLAiIGDDINRR

Chain	Residue	Details
B	VAL74-ARG88

---