Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5AJI

MscS D67R1 high resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0008381	molecular_function	mechanosensitive monoatomic ion channel activity
A	0009992	biological_process	intracellular water homeostasis
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0042802	molecular_function	identical protein binding
A	0051260	biological_process	protein homooligomerization
A	0055085	biological_process	transmembrane transport
B	0005886	cellular_component	plasma membrane
B	0008381	molecular_function	mechanosensitive monoatomic ion channel activity
B	0009992	biological_process	intracellular water homeostasis
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0042802	molecular_function	identical protein binding
B	0051260	biological_process	protein homooligomerization
B	0055085	biological_process	transmembrane transport
C	0005886	cellular_component	plasma membrane
C	0008381	molecular_function	mechanosensitive monoatomic ion channel activity
C	0009992	biological_process	intracellular water homeostasis
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0042802	molecular_function	identical protein binding
C	0051260	biological_process	protein homooligomerization
C	0055085	biological_process	transmembrane transport
D	0005886	cellular_component	plasma membrane
D	0008381	molecular_function	mechanosensitive monoatomic ion channel activity
D	0009992	biological_process	intracellular water homeostasis
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0042802	molecular_function	identical protein binding
D	0051260	biological_process	protein homooligomerization
D	0055085	biological_process	transmembrane transport
E	0005886	cellular_component	plasma membrane
E	0008381	molecular_function	mechanosensitive monoatomic ion channel activity
E	0009992	biological_process	intracellular water homeostasis
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0042802	molecular_function	identical protein binding
E	0051260	biological_process	protein homooligomerization
E	0055085	biological_process	transmembrane transport
F	0005886	cellular_component	plasma membrane
F	0008381	molecular_function	mechanosensitive monoatomic ion channel activity
F	0009992	biological_process	intracellular water homeostasis
F	0016020	cellular_component	membrane
F	0034220	biological_process	monoatomic ion transmembrane transport
F	0042802	molecular_function	identical protein binding
F	0051260	biological_process	protein homooligomerization
F	0055085	biological_process	transmembrane transport
G	0005886	cellular_component	plasma membrane
G	0008381	molecular_function	mechanosensitive monoatomic ion channel activity
G	0009992	biological_process	intracellular water homeostasis
G	0016020	cellular_component	membrane
G	0034220	biological_process	monoatomic ion transmembrane transport
G	0042802	molecular_function	identical protein binding
G	0051260	biological_process	protein homooligomerization
G	0055085	biological_process	transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE HEX A 501

Chain	Residue
A	VAL65

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE HEX B 500

Chain	Residue
B	MET126

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE HEX B 501

Chain	Residue
B	VAL65
B	PHE68

site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE HEX C 501

Chain	Residue
C	PHE68

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE HEX D 501

Chain	Residue
D	VAL65
D	PHE68

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE HEX E 500

Chain	Residue
E	LEU123

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE HEX E 501

Chain	Residue
E	VAL65

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE HEX F 501

Chain	Residue
F	VAL65
F	PHE68

Functional Information from PROSITE/UniProt

site_id	PS01246
Number of Residues	35
Details	UPF0003 Uncharacterized protein family UPF0003 signature. GTVlsVqifsttMrtaDgkiIvIPNgkIIagniiN

Chain	Residue	Details
A	GLY143-ASN177

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	210
Details	TOPO_DOM: Periplasmic => ECO:0000305\|PubMed:15919996

Chain	Residue	Details
A	MET1-ASN30
E	VAL89-GLY90
F	MET1-ASN30
F	VAL89-GLY90
G	MET1-ASN30
G	VAL89-GLY90
A	VAL89-GLY90
B	MET1-ASN30
B	VAL89-GLY90
C	MET1-ASN30
C	VAL89-GLY90
D	MET1-ASN30
D	VAL89-GLY90
E	MET1-ASN30

site_id	SWS_FT_FI2
Number of Residues	427
Details	TRANSMEM: Helical => ECO:0000269\|PubMed:12446901, ECO:0000269\|PubMed:26551077

Chain	Residue	Details
A	ILE31-VAL52
D	ILE31-VAL52
D	PHE68-ARG88
D	VAL91-LEU111
E	ILE31-VAL52
E	PHE68-ARG88
E	VAL91-LEU111
F	ILE31-VAL52
F	PHE68-ARG88
F	VAL91-LEU111
G	ILE31-VAL52
A	PHE68-ARG88
G	PHE68-ARG88
G	VAL91-LEU111
A	VAL91-LEU111
B	ILE31-VAL52
B	PHE68-ARG88
B	VAL91-LEU111
C	ILE31-VAL52
C	PHE68-ARG88
C	VAL91-LEU111

site_id	SWS_FT_FI3
Number of Residues	1316
Details	TOPO_DOM: Cytoplasmic => ECO:0000305\|PubMed:15919996

Chain	Residue	Details
A	ASN53-R1A67
E	GLN112-ALA286
F	ASN53-R1A67
F	GLN112-ALA286
G	ASN53-R1A67
G	GLN112-ALA286
A	GLN112-ALA286
B	ASN53-R1A67
B	GLN112-ALA286
C	ASN53-R1A67
C	GLN112-ALA286
D	ASN53-R1A67
D	GLN112-ALA286
E	ASN53-R1A67

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)