5AHK
Crystal structure of acetohydroxy acid synthase Pf5 from Pseudomonas protegens
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003984 | molecular_function | acetolactate synthase activity |
| A | 0005948 | cellular_component | acetolactate synthase complex |
| A | 0009097 | biological_process | isoleucine biosynthetic process |
| A | 0009099 | biological_process | L-valine biosynthetic process |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
| A | 0030976 | molecular_function | thiamine pyrophosphate binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003984 | molecular_function | acetolactate synthase activity |
| B | 0005948 | cellular_component | acetolactate synthase complex |
| B | 0009097 | biological_process | isoleucine biosynthetic process |
| B | 0009099 | biological_process | L-valine biosynthetic process |
| B | 0019752 | biological_process | carboxylic acid metabolic process |
| B | 0030976 | molecular_function | thiamine pyrophosphate binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE TPP A 700 |
| Chain | Residue |
| A | VAL394 |
| A | GLY448 |
| A | ASN473 |
| A | SER475 |
| A | LEU476 |
| A | GLY477 |
| A | MET478 |
| A | VAL479 |
| A | MG702 |
| A | HOH2339 |
| A | HOH2353 |
| A | GLY395 |
| B | LEU22 |
| B | ILE23 |
| B | GLU48 |
| B | PRO76 |
| B | ASN80 |
| B | GLN119 |
| A | ASN396 |
| A | ASN397 |
| A | GLY420 |
| A | MET422 |
| A | GLY445 |
| A | ASP446 |
| A | GLY447 |
| site_id | AC2 |
| Number of Residues | 37 |
| Details | BINDING SITE FOR RESIDUE FAD A 701 |
| Chain | Residue |
| A | ARG158 |
| A | GLY218 |
| A | GLY219 |
| A | GLY220 |
| A | SER224 |
| A | SER244 |
| A | LEU245 |
| A | LYS246 |
| A | MET260 |
| A | LEU261 |
| A | ALA263 |
| A | TYR264 |
| A | GLY283 |
| A | SER284 |
| A | ARG285 |
| A | ASP287 |
| A | ARG289 |
| A | GLN290 |
| A | ASP308 |
| A | LEU309 |
| A | GLN310 |
| A | GLN313 |
| A | ILE326 |
| A | GLU327 |
| A | LEU328 |
| A | GLN398 |
| A | MET399 |
| A | SER416 |
| A | GLY417 |
| A | GLY418 |
| A | HOH2089 |
| A | HOH2091 |
| A | HOH2092 |
| A | HOH2205 |
| A | HOH2254 |
| A | HOH2418 |
| B | PHE118 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 702 |
| Chain | Residue |
| A | ASP446 |
| A | ASN473 |
| A | SER475 |
| A | TPP700 |
| A | HOH2353 |
| site_id | AC4 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE TPP B 700 |
| Chain | Residue |
| A | LEU22 |
| A | ILE23 |
| A | GLU48 |
| A | PRO76 |
| A | ASN80 |
| A | GLN119 |
| B | VAL394 |
| B | GLY395 |
| B | ASN396 |
| B | ASN397 |
| B | GLY420 |
| B | MET422 |
| B | GLY445 |
| B | ASP446 |
| B | GLY447 |
| B | GLY448 |
| B | ASN473 |
| B | SER475 |
| B | LEU476 |
| B | GLY477 |
| B | MET478 |
| B | MG702 |
| B | HOH2375 |
| B | HOH2391 |
| site_id | AC5 |
| Number of Residues | 37 |
| Details | BINDING SITE FOR RESIDUE FAD B 701 |
| Chain | Residue |
| B | LYS246 |
| B | MET260 |
| B | LEU261 |
| B | ALA263 |
| B | TYR264 |
| B | GLY283 |
| B | SER284 |
| B | ARG285 |
| B | ASP287 |
| B | ARG289 |
| B | GLN290 |
| B | ASP308 |
| B | LEU309 |
| B | GLN310 |
| B | GLN313 |
| B | ILE326 |
| B | GLU327 |
| B | LEU328 |
| B | GLN398 |
| B | MET399 |
| B | GLY417 |
| B | GLY418 |
| B | MET478 |
| B | HOH2068 |
| B | HOH2069 |
| B | HOH2070 |
| B | HOH2203 |
| B | HOH2272 |
| B | HOH2466 |
| A | PHE118 |
| B | ARG158 |
| B | GLY218 |
| B | GLY219 |
| B | GLY220 |
| B | SER224 |
| B | SER244 |
| B | LEU245 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 702 |
| Chain | Residue |
| B | ASP446 |
| B | ASN473 |
| B | SER475 |
| B | TPP700 |
| B | HOH2391 |
