5AH5
Crystal structure of the ternary complex of Agrobacterium radiobacter K84 agnB2 LeuRS-tRNA-LeuAMS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0002161 | molecular_function | aminoacyl-tRNA deacylase activity |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004823 | molecular_function | leucine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006412 | biological_process | translation |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006429 | biological_process | leucyl-tRNA aminoacylation |
| A | 0016874 | molecular_function | ligase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0106074 | biological_process | aminoacyl-tRNA metabolism involved in translational fidelity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0002161 | molecular_function | aminoacyl-tRNA deacylase activity |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004823 | molecular_function | leucine-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006412 | biological_process | translation |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006429 | biological_process | leucyl-tRNA aminoacylation |
| B | 0016874 | molecular_function | ligase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0106074 | biological_process | aminoacyl-tRNA metabolism involved in translational fidelity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 900 |
| Chain | Residue |
| A | CYS432 |
| A | CYS435 |
| A | CYS473 |
| A | CYS476 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 900 |
| Chain | Residue |
| B | CYS432 |
| B | CYS435 |
| B | CYS473 |
| B | CYS476 |
| site_id | AC3 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE LSS A 1818 |
| Chain | Residue |
| A | PHE39 |
| A | PRO40 |
| A | TYR41 |
| A | HIS47 |
| A | GLY49 |
| A | HIS50 |
| A | ASN53 |
| A | TYR54 |
| A | ASP78 |
| A | SER493 |
| A | TYR496 |
| A | TYR523 |
| A | GLY525 |
| A | GLY526 |
| A | GLU528 |
| A | HIS529 |
| A | HIS533 |
| A | GLN562 |
| A | GLY563 |
| A | MET564 |
| A | VAL565 |
| A | HOH2034 |
| A | HOH2231 |
| A | MET38 |
| site_id | AC4 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE LSS B 1818 |
| Chain | Residue |
| B | MET38 |
| B | PHE39 |
| B | PRO40 |
| B | TYR41 |
| B | HIS47 |
| B | GLY49 |
| B | HIS50 |
| B | ASN53 |
| B | TYR54 |
| B | ASP78 |
| B | SER493 |
| B | TYR496 |
| B | TYR523 |
| B | GLY525 |
| B | GLY526 |
| B | GLU528 |
| B | HIS529 |
| B | HIS533 |
| B | GLN562 |
| B | GLY563 |
| B | MET564 |
| B | VAL565 |
| B | HOH2064 |
| B | HOH2266 |
| B | HOH2384 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE MN C 1077 |
| Chain | Residue |
| C | G1 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE MN D 1077 |
| Chain | Residue |
| D | G1 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1078 |
| Chain | Residue |
| A | SER213 |
| C | G5 |
| C | G69 |
| C | G70 |
| C | HOH2086 |
| C | HOH2089 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1078 |
| Chain | Residue |
| B | SER213 |
| D | G5 |
| D | G69 |
| D | G70 |
| D | HOH2074 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1819 |
| Chain | Residue |
| A | ARG766 |
| A | THR767 |
| A | MET768 |
| A | THR769 |
| A | HOH2302 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1819 |
| Chain | Residue |
| B | LYS31 |
| B | ARG67 |
| B | TYR69 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1820 |
| Chain | Residue |
| B | ARG766 |
| B | THR767 |
| B | MET768 |
| B | THR769 |
| B | HOH2366 |
Functional Information from PROSITE/UniProt
| site_id | PS00178 |
| Number of Residues | 12 |
| Details | AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. PytSGhLHIGHV |
| Chain | Residue | Details |
| A | PRO40-VAL51 |
