5AH4

The sliding clamp of Mycobacterium smegmatis in complex with a natural product.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005737	cellular_component	cytoplasm
A	0006260	biological_process	DNA replication
A	0006271	biological_process	DNA strand elongation involved in DNA replication
A	0008408	molecular_function	3'-5' exonuclease activity
A	0009360	cellular_component	DNA polymerase III complex
A	0046677	biological_process	response to antibiotic
A	0071897	biological_process	DNA biosynthetic process
B	0003677	molecular_function	DNA binding
B	0003887	molecular_function	DNA-directed DNA polymerase activity
B	0005737	cellular_component	cytoplasm
B	0006260	biological_process	DNA replication
B	0006271	biological_process	DNA strand elongation involved in DNA replication
B	0008408	molecular_function	3'-5' exonuclease activity
B	0009360	cellular_component	DNA polymerase III complex
B	0046677	biological_process	response to antibiotic
B	0071897	biological_process	DNA biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA A 1398

Chain	Residue
A	GLU327
A	PRO328
A	LEU329
A	HOH2058

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site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR CHAIN C OF CYCLOHEXYL GRISELIMYCIN

Chain	Residue
A	LYS258
A	LEU262
A	MET391
A	PRO392
A	VAL393
A	ARG394
A	HOH2023
A	HOH2087
A	HOH2088
A	HOH2091
A	HOH2092
B	LEU159
D	MLU10
A	ARG181
A	PHE182
A	ARG183
A	GLU255
A	PRO257

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site_id	AC3
Number of Residues	13
Details	BINDING SITE FOR CHAIN D OF CYCLOHEXYL GRISELIMYCIN

Chain	Residue
B	THR179
B	ARG181
B	PHE182
B	ARG183
B	GLU255
B	LYS258
B	LEU262
B	MET391
B	PRO392
B	ARG394
B	HOH2101
B	HOH2102
C	MLU10

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