5AGT
Crystal structure of the LeuRS editing domain of Mycobacterium tuberculosis in complex with the adduct (S)-3-(Aminomethyl)-4-chloro-7-ethoxybenzo[c][1,2]oxaborol-1(3H)-ol-AMP
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0002161 | molecular_function | aminoacyl-tRNA editing activity |
A | 0004823 | molecular_function | leucine-tRNA ligase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
A | 0006429 | biological_process | leucyl-tRNA aminoacylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 23 |
Details | BINDING SITE FOR RESIDUE A2H A 1514 |
Chain | Residue |
A | PHE335 |
A | ILE440 |
A | MET441 |
A | HIS446 |
A | ASP447 |
A | ARG449 |
A | ASP450 |
A | HOH2024 |
A | HOH2129 |
A | HOH2149 |
A | HOH2150 |
A | THR336 |
A | HOH2294 |
A | HOH2295 |
A | HOH2296 |
A | HOH2297 |
A | THR337 |
A | ARG338 |
A | THR341 |
A | TYR430 |
A | VAL431 |
A | LEU432 |
A | TYR435 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MET A 1516 |
Chain | Residue |
A | PRO417 |
A | ALA506 |
A | HOH2302 |
A | HOH2303 |
A | HOH2304 |
site_id | AC3 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL A 1515 |
Chain | Residue |
A | THR346 |
A | GLU421 |
A | PRO422 |
A | VAL423 |
A | PRO460 |
A | HOH2033 |
A | HOH2301 |