5AF2
Crystal structure of the C-terminal 2',5'-phosphodiesterase domain of group A rotavirus protein VP3
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE 15P A 1836 |
| Chain | Residue |
| A | PHE775 |
| A | HOH2167 |
| A | HOH2168 |
| B | PHE775 |
| B | TYR778 |
| B | GLN790 |
| B | ARG792 |
| B | MET793 |
| B | HOH2125 |
| C | TYR754 |
| C | ARG809 |
| A | TYR778 |
| A | GLN790 |
| A | ARG792 |
| A | MET793 |
| A | PHE794 |
| A | K1837 |
| A | K1838 |
| A | HOH2114 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE K A 1837 |
| Chain | Residue |
| A | 15P1836 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE K A 1838 |
| Chain | Residue |
| A | 15P1836 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | ACT_SITE: For 2'-5'-phosphodiesterase activity => ECO:0000255|HAMAP-Rule:MF_04128, ECO:0000269|PubMed:23878220, ECO:0000305|PubMed:25758703 |
| Chain | Residue | Details |
| A | HIS718 | |
| A | HIS797 | |
| B | HIS718 | |
| B | HIS797 | |
| C | HIS718 | |
| C | HIS797 | |
| D | HIS718 | |
| D | HIS797 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | ACT_SITE: For 2'-5'-phosphodiesterase activity => ECO:0000255|HAMAP-Rule:MF_04128, ECO:0000305|PubMed:25758703 |
| Chain | Residue | Details |
| A | THR720 | |
| A | THR799 | |
| B | THR720 | |
| B | THR799 | |
| C | THR720 | |
| C | THR799 | |
| D | THR720 | |
| D | THR799 |
