5AA1

Crystal structure of MltF from Pseudomonas aeruginosa in complex with NAG-anhNAM-pentapeptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000270	biological_process	peptidoglycan metabolic process
A	0008933	molecular_function	peptidoglycan lytic transglycosylase activity
A	0016020	cellular_component	membrane
A	0016837	molecular_function	carbon-oxygen lyase activity, acting on polysaccharides
B	0000270	biological_process	peptidoglycan metabolic process
B	0008933	molecular_function	peptidoglycan lytic transglycosylase activity
B	0016020	cellular_component	membrane
B	0016837	molecular_function	carbon-oxygen lyase activity, acting on polysaccharides
C	0000270	biological_process	peptidoglycan metabolic process
C	0008933	molecular_function	peptidoglycan lytic transglycosylase activity
C	0016020	cellular_component	membrane
C	0016837	molecular_function	carbon-oxygen lyase activity, acting on polysaccharides
D	0000270	biological_process	peptidoglycan metabolic process
D	0008933	molecular_function	peptidoglycan lytic transglycosylase activity
D	0016020	cellular_component	membrane
D	0016837	molecular_function	carbon-oxygen lyase activity, acting on polysaccharides

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 1460

Chain	Residue
A	SER379

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL B 1459

Chain	Residue
B	ARG136
B	ASN137
B	ASN216

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL D 1460

Chain	Residue
D	ARG330

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site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL B 1460

Chain	Residue
B	SER160

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site_id	AC5
Number of Residues	6
Details	Binding site for Di-peptide AH0 E 1 and ALA E 2

Chain	Residue
A	HOH2010
A	HOH2011
E	FGA3
A	TYR94
A	GLY158
A	GLU163

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site_id	AC6
Number of Residues	15
Details	Binding site for Di-peptide ALA E 2 and FGA E 3

Chain	Residue
A	LEU90
A	TYR94
A	GLY109
A	LEU110
A	THR111
A	GLY158
A	SER159
A	SER160
A	HIS161
A	GLU163
A	ASP203
A	HOH2010
E	AH01
E	API4
E	DAL5

---

site_id	AC7
Number of Residues	21
Details	Binding site for residues FGA E 3 and API E 4

Chain	Residue
A	ARG50
A	LEU90
A	TYR94
A	GLY109
A	LEU110
A	THR111
A	VAL155
A	LEU156
A	GLY158
A	SER159
A	SER160
A	HIS161
A	VAL185
A	LEU188
A	LEU201
A	VAL202
A	ASP203
A	GLU206
A	HOH2021
E	ALA2
E	DAL5

---

site_id	AC8
Number of Residues	17
Details	Binding site for Di-peptide API E 4 and DAL E 5

Chain	Residue
A	ARG50
A	ALA108
A	GLY109
A	VAL155
A	LEU156
A	SER159
A	HIS161
A	VAL185
A	LEU188
A	LEU201
A	VAL202
A	ASP203
A	ASN205
A	GLU206
A	HOH2021
E	FGA3
E	DAL6

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site_id	AC9
Number of Residues	14
Details	Binding site for Di-peptide DAL E 5 and DAL E 6

Chain	Residue
A	ARG50
A	ALA54
A	THR55
A	PHE66
A	GLU67
A	ALA108
A	GLY109
A	ASP203
A	ASN205
A	GLU206
A	LEU229
A	TYR266
E	FGA3
E	API4

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Functional Information from PROSITE/UniProt

site_id	PS00922
Number of Residues	29
Details	TRANSGLYCOSYLASE Prokaryotic transglycosylases signature. IgyqESlwqPgatSktgvrGLMmLtnrtA

Chain	Residue	Details
A	ILE312-ALA340

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_02016","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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