5AA1
Crystal structure of MltF from Pseudomonas aeruginosa in complex with NAG-anhNAM-pentapeptide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000270 | biological_process | peptidoglycan metabolic process |
| A | 0008933 | molecular_function | lytic transglycosylase activity |
| A | 0016020 | cellular_component | membrane |
| A | 0016837 | molecular_function | carbon-oxygen lyase activity, acting on polysaccharides |
| B | 0000270 | biological_process | peptidoglycan metabolic process |
| B | 0008933 | molecular_function | lytic transglycosylase activity |
| B | 0016020 | cellular_component | membrane |
| B | 0016837 | molecular_function | carbon-oxygen lyase activity, acting on polysaccharides |
| C | 0000270 | biological_process | peptidoglycan metabolic process |
| C | 0008933 | molecular_function | lytic transglycosylase activity |
| C | 0016020 | cellular_component | membrane |
| C | 0016837 | molecular_function | carbon-oxygen lyase activity, acting on polysaccharides |
| D | 0000270 | biological_process | peptidoglycan metabolic process |
| D | 0008933 | molecular_function | lytic transglycosylase activity |
| D | 0016020 | cellular_component | membrane |
| D | 0016837 | molecular_function | carbon-oxygen lyase activity, acting on polysaccharides |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 1460 |
| Chain | Residue |
| A | SER379 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 1459 |
| Chain | Residue |
| B | ARG136 |
| B | ASN137 |
| B | ASN216 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL D 1460 |
| Chain | Residue |
| D | ARG330 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 1460 |
| Chain | Residue |
| B | SER160 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | Binding site for Di-peptide AH0 E 1 and ALA E 2 |
| Chain | Residue |
| A | HOH2010 |
| A | HOH2011 |
| E | FGA3 |
| A | TYR94 |
| A | GLY158 |
| A | GLU163 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | Binding site for Di-peptide ALA E 2 and FGA E 3 |
| Chain | Residue |
| A | LEU90 |
| A | TYR94 |
| A | GLY109 |
| A | LEU110 |
| A | THR111 |
| A | GLY158 |
| A | SER159 |
| A | SER160 |
| A | HIS161 |
| A | GLU163 |
| A | ASP203 |
| A | HOH2010 |
| E | AH01 |
| E | API4 |
| E | DAL5 |
| site_id | AC7 |
| Number of Residues | 21 |
| Details | Binding site for residues FGA E 3 and API E 4 |
| Chain | Residue |
| A | ARG50 |
| A | LEU90 |
| A | TYR94 |
| A | GLY109 |
| A | LEU110 |
| A | THR111 |
| A | VAL155 |
| A | LEU156 |
| A | GLY158 |
| A | SER159 |
| A | SER160 |
| A | HIS161 |
| A | VAL185 |
| A | LEU188 |
| A | LEU201 |
| A | VAL202 |
| A | ASP203 |
| A | GLU206 |
| A | HOH2021 |
| E | ALA2 |
| E | DAL5 |
| site_id | AC8 |
| Number of Residues | 17 |
| Details | Binding site for Di-peptide API E 4 and DAL E 5 |
| Chain | Residue |
| A | ARG50 |
| A | ALA108 |
| A | GLY109 |
| A | VAL155 |
| A | LEU156 |
| A | SER159 |
| A | HIS161 |
| A | VAL185 |
| A | LEU188 |
| A | LEU201 |
| A | VAL202 |
| A | ASP203 |
| A | ASN205 |
| A | GLU206 |
| A | HOH2021 |
| E | FGA3 |
| E | DAL6 |
| site_id | AC9 |
| Number of Residues | 14 |
| Details | Binding site for Di-peptide DAL E 5 and DAL E 6 |
| Chain | Residue |
| A | ARG50 |
| A | ALA54 |
| A | THR55 |
| A | PHE66 |
| A | GLU67 |
| A | ALA108 |
| A | GLY109 |
| A | ASP203 |
| A | ASN205 |
| A | GLU206 |
| A | LEU229 |
| A | TYR266 |
| E | FGA3 |
| E | API4 |
Functional Information from PROSITE/UniProt
| site_id | PS00922 |
| Number of Residues | 29 |
| Details | TRANSGLYCOSYLASE Prokaryotic transglycosylases signature. IgyqESlwqPgatSktgvrGLMmLtnrtA |
| Chain | Residue | Details |
| A | ILE312-ALA340 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_02016 |
| Chain | Residue | Details |
| A | GLU316 | |
| B | GLU316 | |
| C | GLU316 | |
| D | GLU316 |
