5A9K

Structural basis for DNA strand separation by a hexameric replicative helicase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003678	molecular_function	DNA helicase activity
A	0005524	molecular_function	ATP binding
A	0006260	biological_process	DNA replication
B	0003677	molecular_function	DNA binding
B	0003678	molecular_function	DNA helicase activity
B	0005524	molecular_function	ATP binding
B	0006260	biological_process	DNA replication
C	0003677	molecular_function	DNA binding
C	0003678	molecular_function	DNA helicase activity
C	0005524	molecular_function	ATP binding
C	0006260	biological_process	DNA replication
D	0003677	molecular_function	DNA binding
D	0003678	molecular_function	DNA helicase activity
D	0005524	molecular_function	ATP binding
D	0006260	biological_process	DNA replication
E	0003677	molecular_function	DNA binding
E	0003678	molecular_function	DNA helicase activity
E	0005524	molecular_function	ATP binding
E	0006260	biological_process	DNA replication
F	0003677	molecular_function	DNA binding
F	0003678	molecular_function	DNA helicase activity
F	0005524	molecular_function	ATP binding
F	0006260	biological_process	DNA replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 A 1580

Chain	Residue
A	ASN436
A	THR437
A	GLY438
A	LYS439
A	SER440
A	PO41581
A	MG1582

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 A 1581

Chain	Residue
A	LYS439
A	ASP479
A	ASN523
A	PO41580
A	MG1582
B	ARG538
A	PRO435
A	ASN436

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 1582

Chain	Residue
A	SER440
A	ASP479
A	PO41580
A	PO41581
B	ARG538

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 B 1579

Chain	Residue
B	ASN436
B	THR437
B	GLY438
B	LYS439
B	SER440
B	MET441
B	PO41580
B	MG1581

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 B 1580

Chain	Residue
B	PRO435
B	ASN436
B	LYS439
B	ASP479
B	ASN523
B	PO41579
B	MG1581
C	ARG538

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B 1581

Chain	Residue
B	SER440
B	ASP479
B	PO41579
B	PO41580
C	ARG538

---

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 C 1579

Chain	Residue
C	ASN436
C	THR437
C	GLY438
C	LYS439
C	SER440
C	MET441
C	PO41580
C	MG1581

---

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 C 1580

Chain	Residue
C	PRO435
C	ASN436
C	LYS439
C	ASP479
C	ASN523
C	PO41579
C	MG1581
D	ARG538

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 1581

Chain	Residue
C	SER440
C	ASP479
C	PO41579
C	PO41580

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 D 1580

Chain	Residue
D	ASN436
D	THR437
D	GLY438
D	LYS439
D	SER440

---

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 E 1579

Chain	Residue
E	ASN436
E	THR437
E	GLY438
E	LYS439
E	SER440
F	TYR534

---

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 F 1580

Chain	Residue
F	ASN436
F	THR437
F	GLY438
F	LYS439
F	SER440

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_04000

Chain	Residue	Details
A	GLY433
B	GLY433
C	GLY433
D	GLY433
E	GLY433
F	GLY433

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000255|HAMAP-Rule:MF_04000, ECO:0000269|PubMed:11005821

Chain	Residue	Details
A	LYS514
F	LYS514
B	LYS514
C	LYS514
D	LYS514
E	LYS514

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