Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006915 | biological_process | apoptotic process |
| A | 0016567 | biological_process | protein ubiquitination |
| A | 0016740 | molecular_function | transferase activity |
| A | 0043065 | biological_process | positive regulation of apoptotic process |
| A | 0043066 | biological_process | negative regulation of apoptotic process |
| A | 0060090 | molecular_function | molecular adaptor activity |
| A | 0061631 | molecular_function | ubiquitin conjugating enzyme activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MLI A 1328 |
| Chain | Residue |
| A | GLY171 |
| A | THR174 |
| A | ARG250 |
| A | ASP255 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MLI A 1329 |
| Chain | Residue |
| A | LYS287 |
| A | ASP288 |
| A | ASP124 |
| A | THR125 |
| A | HIS132 |
| A | PRO264 |
| A | VAL284 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MLI A 1330 |
| Chain | Residue |
| A | ALA203 |
| A | GLN204 |
| A | SER205 |
| A | SER208 |
| A | ILE211 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MLI A 1331 |
| Chain | Residue |
| A | GLU258 |
| A | ARG316 |
| A | LEU319 |
| A | HOH2022 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG A 1332 |
| Chain | Residue |
| A | ARG250 |
| A | HIS307 |
| A | ASP309 |
| A | SER312 |
| A | LEU313 |
| A | ARG316 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MLI A 1333 |
| Chain | Residue |
| A | THR125 |
| A | VAL126 |
| A | ASP127 |
| A | MET128 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG A 1334 |
| Chain | Residue |
| A | CYS100 |
| A | LEU101 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Glycyl thioester intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"}]} |
