Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5A2Q

Structure of the HCV IRES bound to the human ribosome

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000028	biological_process	ribosomal small subunit assembly
A	0001618	molecular_function	virus receptor activity
A	0002181	biological_process	cytoplasmic translation
A	0003677	molecular_function	DNA binding
A	0003723	molecular_function	RNA binding
A	0003735	molecular_function	structural constituent of ribosome
A	0005055	molecular_function	laminin receptor activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005840	cellular_component	ribosome
A	0005886	cellular_component	plasma membrane
A	0006338	biological_process	chromatin remodeling
A	0006412	biological_process	translation
A	0007155	biological_process	cell adhesion
A	0015935	cellular_component	small ribosomal subunit
A	0016020	cellular_component	membrane
A	0022626	cellular_component	cytosolic ribosome
A	0022627	cellular_component	cytosolic small ribosomal subunit
A	0043022	molecular_function	ribosome binding
A	0043236	molecular_function	laminin binding
A	0046718	biological_process	symbiont entry into host cell
A	0070062	cellular_component	extracellular exosome
A	0140374	biological_process	antiviral innate immune response
A	1990904	cellular_component	ribonucleoprotein complex
B	0002181	biological_process	cytoplasmic translation
B	0003723	molecular_function	RNA binding
B	0003735	molecular_function	structural constituent of ribosome
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005730	cellular_component	nucleolus
B	0005737	cellular_component	cytoplasm
B	0005783	cellular_component	endoplasmic reticulum
B	0005829	cellular_component	cytosol
B	0005840	cellular_component	ribosome
B	0005925	cellular_component	focal adhesion
B	0006412	biological_process	translation
B	0006413	biological_process	translational initiation
B	0022626	cellular_component	cytosolic ribosome
B	0022627	cellular_component	cytosolic small ribosomal subunit
B	0030154	biological_process	cell differentiation
B	0032040	cellular_component	small-subunit processome
B	0042274	biological_process	ribosomal small subunit biogenesis
B	0043066	biological_process	negative regulation of apoptotic process
B	0045202	cellular_component	synapse
B	0048027	molecular_function	mRNA 5'-UTR binding
B	0070062	cellular_component	extracellular exosome
B	1990904	cellular_component	ribonucleoprotein complex
C	0002181	biological_process	cytoplasmic translation
C	0003723	molecular_function	RNA binding
C	0003729	molecular_function	mRNA binding
C	0003735	molecular_function	structural constituent of ribosome
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005730	cellular_component	nucleolus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005840	cellular_component	ribosome
C	0005925	cellular_component	focal adhesion
C	0006412	biological_process	translation
C	0015935	cellular_component	small ribosomal subunit
C	0016020	cellular_component	membrane
C	0017134	molecular_function	fibroblast growth factor binding
C	0019899	molecular_function	enzyme binding
C	0022626	cellular_component	cytosolic ribosome
C	0022627	cellular_component	cytosolic small ribosomal subunit
C	0045296	molecular_function	cadherin binding
C	0051443	biological_process	positive regulation of ubiquitin-protein transferase activity
C	0070062	cellular_component	extracellular exosome
C	1990904	cellular_component	ribonucleoprotein complex
D	0000977	molecular_function	RNA polymerase II transcription regulatory region sequence-specific DNA binding
D	0002181	biological_process	cytoplasmic translation
D	0003677	molecular_function	DNA binding
D	0003684	molecular_function	damaged DNA binding
D	0003723	molecular_function	RNA binding
D	0003729	molecular_function	mRNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0003906	molecular_function	DNA-(apurinic or apyrimidinic site) endonuclease activity
D	0004520	molecular_function	DNA endonuclease activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005730	cellular_component	nucleolus
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0005759	cellular_component	mitochondrial matrix
D	0005783	cellular_component	endoplasmic reticulum
D	0005819	cellular_component	spindle
D	0005829	cellular_component	cytosol
D	0005840	cellular_component	ribosome
D	0005856	cellular_component	cytoskeleton
D	0005886	cellular_component	plasma membrane
D	0005925	cellular_component	focal adhesion
D	0006281	biological_process	DNA repair
D	0006284	biological_process	base-excision repair
D	0006412	biological_process	translation
D	0006413	biological_process	translational initiation
D	0006417	biological_process	regulation of translation
D	0006915	biological_process	apoptotic process
D	0006974	biological_process	DNA damage response
D	0007059	biological_process	chromosome segregation
D	0008017	molecular_function	microtubule binding
D	0010628	biological_process	positive regulation of gene expression
D	0014069	cellular_component	postsynaptic density
D	0015631	molecular_function	tubulin binding
D	0015935	cellular_component	small ribosomal subunit
D	0016020	cellular_component	membrane
D	0016829	molecular_function	lyase activity
D	0017148	biological_process	negative regulation of translation
D	0019104	molecular_function	DNA N-glycosylase activity
D	0019899	molecular_function	enzyme binding
D	0019900	molecular_function	kinase binding
D	0019901	molecular_function	protein kinase binding
D	0022626	cellular_component	cytosolic ribosome
D	0022627	cellular_component	cytosolic small ribosomal subunit
D	0030544	molecular_function	Hsp70 protein binding
D	0031116	biological_process	positive regulation of microtubule polymerization
D	0031334	biological_process	positive regulation of protein-containing complex assembly
D	0031397	biological_process	negative regulation of protein ubiquitination
D	0032079	biological_process	positive regulation of endodeoxyribonuclease activity
D	0032357	molecular_function	oxidized purine DNA binding
D	0032358	molecular_function	oxidized pyrimidine DNA binding
D	0032587	cellular_component	ruffle membrane
D	0032743	biological_process	positive regulation of interleukin-2 production
D	0034614	biological_process	cellular response to reactive oxygen species
D	0042104	biological_process	positive regulation of activated T cell proliferation
D	0042981	biological_process	regulation of apoptotic process
D	0044390	molecular_function	ubiquitin-like protein conjugating enzyme binding
D	0044877	molecular_function	protein-containing complex binding
D	0045202	cellular_component	synapse
D	0045738	biological_process	negative regulation of DNA repair
D	0045739	biological_process	positive regulation of DNA repair
D	0050862	biological_process	positive regulation of T cell receptor signaling pathway
D	0051018	molecular_function	protein kinase A binding
D	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
D	0051225	biological_process	spindle assembly
D	0051301	biological_process	cell division
D	0051536	molecular_function	iron-sulfur cluster binding
D	0051879	molecular_function	Hsp90 protein binding
D	0061481	biological_process	response to TNF agonist
D	0070062	cellular_component	extracellular exosome
D	0070181	molecular_function	small ribosomal subunit rRNA binding
D	0070301	biological_process	cellular response to hydrogen peroxide
D	0071159	cellular_component	NF-kappaB complex
D	0071356	biological_process	cellular response to tumor necrosis factor
D	0072686	cellular_component	mitotic spindle
D	0097100	molecular_function	supercoiled DNA binding
D	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D	0140297	molecular_function	DNA-binding transcription factor binding
D	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
D	1902231	biological_process	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
D	1905053	biological_process	positive regulation of base-excision repair
D	1990904	cellular_component	ribonucleoprotein complex
D	2001235	biological_process	positive regulation of apoptotic signaling pathway
E	0002181	biological_process	cytoplasmic translation
E	0003723	molecular_function	RNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005730	cellular_component	nucleolus
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005840	cellular_component	ribosome
E	0005925	cellular_component	focal adhesion
E	0006412	biological_process	translation
E	0008284	biological_process	positive regulation of cell population proliferation
E	0015935	cellular_component	small ribosomal subunit
E	0016020	cellular_component	membrane
E	0019843	molecular_function	rRNA binding
E	0022626	cellular_component	cytosolic ribosome
E	0022627	cellular_component	cytosolic small ribosomal subunit
E	0032040	cellular_component	small-subunit processome
E	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
E	0042274	biological_process	ribosomal small subunit biogenesis
E	0045727	biological_process	positive regulation of translation
E	0070062	cellular_component	extracellular exosome
E	1990904	cellular_component	ribonucleoprotein complex
F	0002181	biological_process	cytoplasmic translation
F	0003723	molecular_function	RNA binding
F	0003729	molecular_function	mRNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005730	cellular_component	nucleolus
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005840	cellular_component	ribosome
F	0005925	cellular_component	focal adhesion
F	0006412	biological_process	translation
F	0006413	biological_process	translational initiation
F	0006450	biological_process	regulation of translational fidelity
F	0015935	cellular_component	small ribosomal subunit
F	0016020	cellular_component	membrane
F	0019843	molecular_function	rRNA binding
F	0022626	cellular_component	cytosolic ribosome
F	0022627	cellular_component	cytosolic small ribosomal subunit
F	0032040	cellular_component	small-subunit processome
F	0042274	biological_process	ribosomal small subunit biogenesis
F	0045202	cellular_component	synapse
F	0070062	cellular_component	extracellular exosome
F	1990904	cellular_component	ribonucleoprotein complex
G	0000028	biological_process	ribosomal small subunit assembly
G	0002181	biological_process	cytoplasmic translation
G	0003723	molecular_function	RNA binding
G	0003729	molecular_function	mRNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005730	cellular_component	nucleolus
G	0005737	cellular_component	cytoplasm
G	0005783	cellular_component	endoplasmic reticulum
G	0005829	cellular_component	cytosol
G	0005840	cellular_component	ribosome
G	0006364	biological_process	rRNA processing
G	0006412	biological_process	translation
G	0008284	biological_process	positive regulation of cell population proliferation
G	0015935	cellular_component	small ribosomal subunit
G	0016020	cellular_component	membrane
G	0019901	molecular_function	protein kinase binding
G	0022626	cellular_component	cytosolic ribosome
G	0022627	cellular_component	cytosolic small ribosomal subunit
G	0030425	cellular_component	dendrite
G	0031929	biological_process	TOR signaling
G	0032040	cellular_component	small-subunit processome
G	0032868	biological_process	response to insulin
G	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
G	0042274	biological_process	ribosomal small subunit biogenesis
G	0042593	biological_process	glucose homeostasis
G	0043065	biological_process	positive regulation of apoptotic process
G	0044297	cellular_component	cell body
G	0071361	biological_process	cellular response to ethanol
G	0098793	cellular_component	presynapse
G	0098982	cellular_component	GABA-ergic synapse
G	1903347	biological_process	negative regulation of bicellular tight junction assembly
G	1990904	cellular_component	ribonucleoprotein complex
H	0001843	biological_process	neural tube closure
H	0002181	biological_process	cytoplasmic translation
H	0003723	molecular_function	RNA binding
H	0003730	molecular_function	mRNA 3'-UTR binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005730	cellular_component	nucleolus
H	0005737	cellular_component	cytoplasm
H	0005783	cellular_component	endoplasmic reticulum
H	0005813	cellular_component	centrosome
H	0005829	cellular_component	cytosol
H	0005840	cellular_component	ribosome
H	0005856	cellular_component	cytoskeleton
H	0005925	cellular_component	focal adhesion
H	0006364	biological_process	rRNA processing
H	0006412	biological_process	translation
H	0010628	biological_process	positive regulation of gene expression
H	0014033	biological_process	neural crest cell differentiation
H	0016020	cellular_component	membrane
H	0019901	molecular_function	protein kinase binding
H	0022626	cellular_component	cytosolic ribosome
H	0022627	cellular_component	cytosolic small ribosomal subunit
H	0032040	cellular_component	small-subunit processome
H	0032991	cellular_component	protein-containing complex
H	0042274	biological_process	ribosomal small subunit biogenesis
H	0045202	cellular_component	synapse
H	0048027	molecular_function	mRNA 5'-UTR binding
H	0050821	biological_process	protein stabilization
H	1902255	biological_process	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
H	1904667	biological_process	negative regulation of ubiquitin protein ligase activity
H	1990904	cellular_component	ribonucleoprotein complex
H	1990948	molecular_function	ubiquitin ligase inhibitor activity
H	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
I	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
I	0002181	biological_process	cytoplasmic translation
I	0003723	molecular_function	RNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005730	cellular_component	nucleolus
I	0005737	cellular_component	cytoplasm
I	0005783	cellular_component	endoplasmic reticulum
I	0005829	cellular_component	cytosol
I	0005840	cellular_component	ribosome
I	0005925	cellular_component	focal adhesion
I	0006412	biological_process	translation
I	0016020	cellular_component	membrane
I	0022626	cellular_component	cytosolic ribosome
I	0022627	cellular_component	cytosolic small ribosomal subunit
I	0032040	cellular_component	small-subunit processome
I	0042274	biological_process	ribosomal small subunit biogenesis
I	0070062	cellular_component	extracellular exosome
I	1990904	cellular_component	ribonucleoprotein complex
J	0002181	biological_process	cytoplasmic translation
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005730	cellular_component	nucleolus
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005840	cellular_component	ribosome
J	0005925	cellular_component	focal adhesion
J	0006412	biological_process	translation
J	0015935	cellular_component	small ribosomal subunit
J	0016020	cellular_component	membrane
J	0019843	molecular_function	rRNA binding
J	0022626	cellular_component	cytosolic ribosome
J	0022627	cellular_component	cytosolic small ribosomal subunit
J	0032040	cellular_component	small-subunit processome
J	0042274	biological_process	ribosomal small subunit biogenesis
J	0045202	cellular_component	synapse
J	0070062	cellular_component	extracellular exosome
J	1990904	cellular_component	ribonucleoprotein complex
K	0002181	biological_process	cytoplasmic translation
K	0003723	molecular_function	RNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005730	cellular_component	nucleolus
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005840	cellular_component	ribosome
K	0005925	cellular_component	focal adhesion
K	0006412	biological_process	translation
K	0016020	cellular_component	membrane
K	0022626	cellular_component	cytosolic ribosome
K	0022627	cellular_component	cytosolic small ribosomal subunit
K	0045202	cellular_component	synapse
K	1990904	cellular_component	ribonucleoprotein complex
L	0002181	biological_process	cytoplasmic translation
L	0003723	molecular_function	RNA binding
L	0003735	molecular_function	structural constituent of ribosome
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005730	cellular_component	nucleolus
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0005840	cellular_component	ribosome
L	0005925	cellular_component	focal adhesion
L	0006412	biological_process	translation
L	0016020	cellular_component	membrane
L	0019843	molecular_function	rRNA binding
L	0022626	cellular_component	cytosolic ribosome
L	0022627	cellular_component	cytosolic small ribosomal subunit
L	0032040	cellular_component	small-subunit processome
L	0042274	biological_process	ribosomal small subunit biogenesis
L	0045202	cellular_component	synapse
L	0070062	cellular_component	extracellular exosome
L	1990904	cellular_component	ribonucleoprotein complex
M	0002181	biological_process	cytoplasmic translation
M	0003723	molecular_function	RNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005730	cellular_component	nucleolus
M	0005737	cellular_component	cytoplasm
M	0005794	cellular_component	Golgi apparatus
M	0005829	cellular_component	cytosol
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0016020	cellular_component	membrane
M	0022626	cellular_component	cytosolic ribosome
M	0022627	cellular_component	cytosolic small ribosomal subunit
M	0032040	cellular_component	small-subunit processome
M	0042274	biological_process	ribosomal small subunit biogenesis
M	0090263	biological_process	positive regulation of canonical Wnt signaling pathway
M	1990145	biological_process	maintenance of translational fidelity
M	1990904	cellular_component	ribonucleoprotein complex
N	0002181	biological_process	cytoplasmic translation
N	0003723	molecular_function	RNA binding
N	0003729	molecular_function	mRNA binding
N	0003735	molecular_function	structural constituent of ribosome
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005730	cellular_component	nucleolus
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0005840	cellular_component	ribosome
N	0005925	cellular_component	focal adhesion
N	0006412	biological_process	translation
N	0014069	cellular_component	postsynaptic density
N	0016020	cellular_component	membrane
N	0022626	cellular_component	cytosolic ribosome
N	0022627	cellular_component	cytosolic small ribosomal subunit
N	0032040	cellular_component	small-subunit processome
N	0033119	biological_process	negative regulation of RNA splicing
N	0042274	biological_process	ribosomal small subunit biogenesis
N	0048027	molecular_function	mRNA 5'-UTR binding
N	0070062	cellular_component	extracellular exosome
N	0070181	molecular_function	small ribosomal subunit rRNA binding
N	1990904	cellular_component	ribonucleoprotein complex
O	0000028	biological_process	ribosomal small subunit assembly
O	0000122	biological_process	negative regulation of transcription by RNA polymerase II
O	0002181	biological_process	cytoplasmic translation
O	0003723	molecular_function	RNA binding
O	0003735	molecular_function	structural constituent of ribosome
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005730	cellular_component	nucleolus
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005840	cellular_component	ribosome
O	0005925	cellular_component	focal adhesion
O	0006412	biological_process	translation
O	0014069	cellular_component	postsynaptic density
O	0016020	cellular_component	membrane
O	0022626	cellular_component	cytosolic ribosome
O	0022627	cellular_component	cytosolic small ribosomal subunit
O	0030218	biological_process	erythrocyte differentiation
O	0030490	biological_process	maturation of SSU-rRNA
O	0032040	cellular_component	small-subunit processome
O	0042274	biological_process	ribosomal small subunit biogenesis
O	0045202	cellular_component	synapse
O	0048027	molecular_function	mRNA 5'-UTR binding
O	0070062	cellular_component	extracellular exosome
O	1990904	cellular_component	ribonucleoprotein complex
P	0000028	biological_process	ribosomal small subunit assembly
P	0000056	biological_process	ribosomal small subunit export from nucleus
P	0001649	biological_process	osteoblast differentiation
P	0002181	biological_process	cytoplasmic translation
P	0003677	molecular_function	DNA binding
P	0003723	molecular_function	RNA binding
P	0003735	molecular_function	structural constituent of ribosome
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005840	cellular_component	ribosome
P	0005925	cellular_component	focal adhesion
P	0006364	biological_process	rRNA processing
P	0006412	biological_process	translation
P	0015935	cellular_component	small ribosomal subunit
P	0016020	cellular_component	membrane
P	0022626	cellular_component	cytosolic ribosome
P	0022627	cellular_component	cytosolic small ribosomal subunit
P	0042274	biological_process	ribosomal small subunit biogenesis
P	0045202	cellular_component	synapse
P	0097371	molecular_function	MDM2/MDM4 family protein binding
P	0097421	biological_process	liver regeneration
P	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
P	1990904	cellular_component	ribonucleoprotein complex
P	1990948	molecular_function	ubiquitin ligase inhibitor activity
Q	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Q	0002181	biological_process	cytoplasmic translation
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005730	cellular_component	nucleolus
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0005840	cellular_component	ribosome
Q	0005925	cellular_component	focal adhesion
Q	0006364	biological_process	rRNA processing
Q	0006412	biological_process	translation
Q	0015935	cellular_component	small ribosomal subunit
Q	0016020	cellular_component	membrane
Q	0022626	cellular_component	cytosolic ribosome
Q	0022627	cellular_component	cytosolic small ribosomal subunit
Q	0032040	cellular_component	small-subunit processome
Q	0042274	biological_process	ribosomal small subunit biogenesis
Q	0045202	cellular_component	synapse
Q	0070062	cellular_component	extracellular exosome
Q	1990830	biological_process	cellular response to leukemia inhibitory factor
Q	1990904	cellular_component	ribonucleoprotein complex
R	0002181	biological_process	cytoplasmic translation
R	0003723	molecular_function	RNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005730	cellular_component	nucleolus
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0005840	cellular_component	ribosome
R	0005925	cellular_component	focal adhesion
R	0006364	biological_process	rRNA processing
R	0006412	biological_process	translation
R	0006413	biological_process	translational initiation
R	0016020	cellular_component	membrane
R	0022626	cellular_component	cytosolic ribosome
R	0022627	cellular_component	cytosolic small ribosomal subunit
R	0032040	cellular_component	small-subunit processome
R	0034101	biological_process	erythrocyte homeostasis
R	0042274	biological_process	ribosomal small subunit biogenesis
R	1990904	cellular_component	ribonucleoprotein complex
S	0002181	biological_process	cytoplasmic translation
S	0003676	molecular_function	nucleic acid binding
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005840	cellular_component	ribosome
S	0005925	cellular_component	focal adhesion
S	0006412	biological_process	translation
S	0014069	cellular_component	postsynaptic density
S	0015935	cellular_component	small ribosomal subunit
S	0016020	cellular_component	membrane
S	0019843	molecular_function	rRNA binding
S	0022626	cellular_component	cytosolic ribosome
S	0022627	cellular_component	cytosolic small ribosomal subunit
S	0045202	cellular_component	synapse
S	0070062	cellular_component	extracellular exosome
S	1990904	cellular_component	ribonucleoprotein complex
T	0000028	biological_process	ribosomal small subunit assembly
T	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
T	0002181	biological_process	cytoplasmic translation
T	0002548	biological_process	monocyte chemotaxis
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005730	cellular_component	nucleolus
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0005840	cellular_component	ribosome
T	0005925	cellular_component	focal adhesion
T	0006364	biological_process	rRNA processing
T	0006412	biological_process	translation
T	0007000	biological_process	nucleolus organization
T	0014069	cellular_component	postsynaptic density
T	0016020	cellular_component	membrane
T	0017134	molecular_function	fibroblast growth factor binding
T	0019901	molecular_function	protein kinase binding
T	0022626	cellular_component	cytosolic ribosome
T	0022627	cellular_component	cytosolic small ribosomal subunit
T	0030218	biological_process	erythrocyte differentiation
T	0030490	biological_process	maturation of SSU-rRNA
T	0031640	biological_process	killing of cells of another organism
T	0032040	cellular_component	small-subunit processome
T	0042274	biological_process	ribosomal small subunit biogenesis
T	0042802	molecular_function	identical protein binding
T	0050829	biological_process	defense response to Gram-negative bacterium
T	0060265	biological_process	positive regulation of respiratory burst involved in inflammatory response
T	0060266	biological_process	negative regulation of respiratory burst involved in inflammatory response
T	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
T	0070062	cellular_component	extracellular exosome
T	1990904	cellular_component	ribonucleoprotein complex
U	0002181	biological_process	cytoplasmic translation
U	0003723	molecular_function	RNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0005515	molecular_function	protein binding
U	0005654	cellular_component	nucleoplasm
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0015935	cellular_component	small ribosomal subunit
U	0016020	cellular_component	membrane
U	0022626	cellular_component	cytosolic ribosome
U	0022627	cellular_component	cytosolic small ribosomal subunit
U	0045202	cellular_component	synapse
U	0070062	cellular_component	extracellular exosome
U	0097371	molecular_function	MDM2/MDM4 family protein binding
U	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
U	1990904	cellular_component	ribonucleoprotein complex
U	1990948	molecular_function	ubiquitin ligase inhibitor activity
V	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
V	0000461	biological_process	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
V	0002181	biological_process	cytoplasmic translation
V	0003723	molecular_function	RNA binding
V	0003735	molecular_function	structural constituent of ribosome
V	0005515	molecular_function	protein binding
V	0005654	cellular_component	nucleoplasm
V	0005737	cellular_component	cytoplasm
V	0005783	cellular_component	endoplasmic reticulum
V	0005791	cellular_component	rough endoplasmic reticulum
V	0005829	cellular_component	cytosol
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0015935	cellular_component	small ribosomal subunit
V	0022626	cellular_component	cytosolic ribosome
V	0022627	cellular_component	cytosolic small ribosomal subunit
V	0045202	cellular_component	synapse
V	1990904	cellular_component	ribonucleoprotein complex
W	0002181	biological_process	cytoplasmic translation
W	0003723	molecular_function	RNA binding
W	0003735	molecular_function	structural constituent of ribosome
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0005654	cellular_component	nucleoplasm
W	0005730	cellular_component	nucleolus
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0005840	cellular_component	ribosome
W	0006412	biological_process	translation
W	0008284	biological_process	positive regulation of cell population proliferation
W	0009615	biological_process	response to virus
W	0016020	cellular_component	membrane
W	0022626	cellular_component	cytosolic ribosome
W	0022627	cellular_component	cytosolic small ribosomal subunit
W	0032040	cellular_component	small-subunit processome
W	0042274	biological_process	ribosomal small subunit biogenesis
W	0045787	biological_process	positive regulation of cell cycle
W	0070062	cellular_component	extracellular exosome
W	1990904	cellular_component	ribonucleoprotein complex
X	0002181	biological_process	cytoplasmic translation
X	0003723	molecular_function	RNA binding
X	0003735	molecular_function	structural constituent of ribosome
X	0005515	molecular_function	protein binding
X	0005634	cellular_component	nucleus
X	0005654	cellular_component	nucleoplasm
X	0005730	cellular_component	nucleolus
X	0005737	cellular_component	cytoplasm
X	0005783	cellular_component	endoplasmic reticulum
X	0005791	cellular_component	rough endoplasmic reticulum
X	0005829	cellular_component	cytosol
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0015935	cellular_component	small ribosomal subunit
X	0016020	cellular_component	membrane
X	0022626	cellular_component	cytosolic ribosome
X	0022627	cellular_component	cytosolic small ribosomal subunit
X	0032040	cellular_component	small-subunit processome
X	0034063	biological_process	stress granule assembly
X	0042274	biological_process	ribosomal small subunit biogenesis
X	0045202	cellular_component	synapse
X	1990145	biological_process	maintenance of translational fidelity
X	1990904	cellular_component	ribonucleoprotein complex
Y	0002181	biological_process	cytoplasmic translation
Y	0003723	molecular_function	RNA binding
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005634	cellular_component	nucleus
Y	0005654	cellular_component	nucleoplasm
Y	0005730	cellular_component	nucleolus
Y	0005737	cellular_component	cytoplasm
Y	0005783	cellular_component	endoplasmic reticulum
Y	0005829	cellular_component	cytosol
Y	0005840	cellular_component	ribosome
Y	0006364	biological_process	rRNA processing
Y	0006412	biological_process	translation
Y	0015935	cellular_component	small ribosomal subunit
Y	0016020	cellular_component	membrane
Y	0022626	cellular_component	cytosolic ribosome
Y	0022627	cellular_component	cytosolic small ribosomal subunit
Y	0031369	molecular_function	translation initiation factor binding
Y	0032040	cellular_component	small-subunit processome
Y	0034101	biological_process	erythrocyte homeostasis
Y	0042274	biological_process	ribosomal small subunit biogenesis
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0002181	biological_process	cytoplasmic translation
Z	0003723	molecular_function	RNA binding
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005515	molecular_function	protein binding
Z	0005634	cellular_component	nucleus
Z	0005654	cellular_component	nucleoplasm
Z	0005730	cellular_component	nucleolus
Z	0005737	cellular_component	cytoplasm
Z	0005829	cellular_component	cytosol
Z	0005840	cellular_component	ribosome
Z	0006364	biological_process	rRNA processing
Z	0006412	biological_process	translation
Z	0014069	cellular_component	postsynaptic density
Z	0015935	cellular_component	small ribosomal subunit
Z	0022626	cellular_component	cytosolic ribosome
Z	0022627	cellular_component	cytosolic small ribosomal subunit
Z	0042274	biological_process	ribosomal small subunit biogenesis
Z	0045202	cellular_component	synapse
Z	0070062	cellular_component	extracellular exosome
Z	1990904	cellular_component	ribonucleoprotein complex
a	0003735	molecular_function	structural constituent of ribosome
a	0005840	cellular_component	ribosome
a	0006412	biological_process	translation
b	0000028	biological_process	ribosomal small subunit assembly
b	0002181	biological_process	cytoplasmic translation
b	0003677	molecular_function	DNA binding
b	0003723	molecular_function	RNA binding
b	0003735	molecular_function	structural constituent of ribosome
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0005654	cellular_component	nucleoplasm
b	0005730	cellular_component	nucleolus
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0005840	cellular_component	ribosome
b	0006364	biological_process	rRNA processing
b	0006412	biological_process	translation
b	0008270	molecular_function	zinc ion binding
b	0014069	cellular_component	postsynaptic density
b	0022626	cellular_component	cytosolic ribosome
b	0022627	cellular_component	cytosolic small ribosomal subunit
b	0032040	cellular_component	small-subunit processome
b	0042274	biological_process	ribosomal small subunit biogenesis
b	0046872	molecular_function	metal ion binding
b	0098793	cellular_component	presynapse
b	0098978	cellular_component	glutamatergic synapse
b	0098982	cellular_component	GABA-ergic synapse
b	1990904	cellular_component	ribonucleoprotein complex
c	0003735	molecular_function	structural constituent of ribosome
c	0005840	cellular_component	ribosome
c	0006412	biological_process	translation
d	0002181	biological_process	cytoplasmic translation
d	0003735	molecular_function	structural constituent of ribosome
d	0005654	cellular_component	nucleoplasm
d	0005737	cellular_component	cytoplasm
d	0005783	cellular_component	endoplasmic reticulum
d	0005791	cellular_component	rough endoplasmic reticulum
d	0005829	cellular_component	cytosol
d	0005840	cellular_component	ribosome
d	0005925	cellular_component	focal adhesion
d	0006412	biological_process	translation
d	0008270	molecular_function	zinc ion binding
d	0015935	cellular_component	small ribosomal subunit
d	0022626	cellular_component	cytosolic ribosome
d	0022627	cellular_component	cytosolic small ribosomal subunit
d	0046872	molecular_function	metal ion binding
d	0070062	cellular_component	extracellular exosome
d	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
d	1990904	cellular_component	ribonucleoprotein complex
e	0003735	molecular_function	structural constituent of ribosome
e	0005840	cellular_component	ribosome
e	0006412	biological_process	translation
f	0003735	molecular_function	structural constituent of ribosome
f	0005840	cellular_component	ribosome
f	0006412	biological_process	translation
g	0001891	cellular_component	phagocytic cup
g	0001934	biological_process	positive regulation of protein phosphorylation
g	0002181	biological_process	cytoplasmic translation
g	0003723	molecular_function	RNA binding
g	0005080	molecular_function	protein kinase C binding
g	0005102	molecular_function	signaling receptor binding
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005654	cellular_component	nucleoplasm
g	0005737	cellular_component	cytoplasm
g	0005739	cellular_component	mitochondrion
g	0005829	cellular_component	cytosol
g	0005840	cellular_component	ribosome
g	0005886	cellular_component	plasma membrane
g	0006412	biological_process	translation
g	0006417	biological_process	regulation of translation
g	0006915	biological_process	apoptotic process
g	0007369	biological_process	gastrulation
g	0008047	molecular_function	enzyme activator activity
g	0008200	molecular_function	ion channel inhibitor activity
g	0008656	molecular_function	cysteine-type endopeptidase activator activity involved in apoptotic process
g	0010629	biological_process	negative regulation of gene expression
g	0015935	cellular_component	small ribosomal subunit
g	0016020	cellular_component	membrane
g	0016567	biological_process	protein ubiquitination
g	0017148	biological_process	negative regulation of translation
g	0019899	molecular_function	enzyme binding
g	0019903	molecular_function	protein phosphatase binding
g	0022627	cellular_component	cytosolic small ribosomal subunit
g	0030178	biological_process	negative regulation of Wnt signaling pathway
g	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
g	0030292	molecular_function	protein tyrosine kinase inhibitor activity
g	0030308	biological_process	negative regulation of cell growth
g	0030332	molecular_function	cyclin binding
g	0030335	biological_process	positive regulation of cell migration
g	0030425	cellular_component	dendrite
g	0030496	cellular_component	midbody
g	0030971	molecular_function	receptor tyrosine kinase binding
g	0031334	biological_process	positive regulation of protein-containing complex assembly
g	0032091	biological_process	negative regulation of protein binding
g	0032436	biological_process	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
g	0032880	biological_process	regulation of protein localization
g	0035591	molecular_function	signaling adaptor activity
g	0042169	molecular_function	SH2 domain binding
g	0042802	molecular_function	identical protein binding
g	0042803	molecular_function	protein homodimerization activity
g	0042995	cellular_component	cell projection
g	0042998	biological_process	positive regulation of Golgi to plasma membrane protein transport
g	0043005	cellular_component	neuron projection
g	0043022	molecular_function	ribosome binding
g	0043025	cellular_component	neuronal cell body
g	0043065	biological_process	positive regulation of apoptotic process
g	0043204	cellular_component	perikaryon
g	0043473	biological_process	pigmentation
g	0043547	biological_process	positive regulation of GTPase activity
g	0044297	cellular_component	cell body
g	0045182	molecular_function	translation regulator activity
g	0045296	molecular_function	cadherin binding
g	0045879	biological_process	negative regulation of smoothened signaling pathway
g	0048471	cellular_component	perinuclear region of cytoplasm
g	0048511	biological_process	rhythmic process
g	0050765	biological_process	negative regulation of phagocytosis
g	0051302	biological_process	regulation of cell division
g	0051434	molecular_function	BH3 domain binding
g	0051726	biological_process	regulation of cell cycle
g	0051898	biological_process	negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
g	0051901	biological_process	positive regulation of mitochondrial depolarization
g	0060090	molecular_function	molecular adaptor activity
g	0070062	cellular_component	extracellular exosome
g	0071333	biological_process	cellular response to glucose stimulus
g	0071363	biological_process	cellular response to growth factor stimulus
g	0072344	biological_process	rescue of stalled ribosome
g	0106070	biological_process	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
g	1900102	biological_process	negative regulation of endoplasmic reticulum unfolded protein response
g	1903751	biological_process	negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
g	1990630	cellular_component	IRE1-RACK1-PP2A complex
g	1990904	cellular_component	ribonucleoprotein complex
g	2000114	biological_process	regulation of establishment of cell polarity
g	2000543	biological_process	positive regulation of gastrulation
g	2001125	biological_process	negative regulation of translational frameshifting
g	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway
h	0002181	biological_process	cytoplasmic translation
h	0003723	molecular_function	RNA binding
h	0003730	molecular_function	mRNA 3'-UTR binding
h	0003735	molecular_function	structural constituent of ribosome
h	0005515	molecular_function	protein binding
h	0005737	cellular_component	cytoplasm
h	0005783	cellular_component	endoplasmic reticulum
h	0005829	cellular_component	cytosol
h	0005840	cellular_component	ribosome
h	0006412	biological_process	translation
h	0022625	cellular_component	cytosolic large ribosomal subunit
h	0048027	molecular_function	mRNA 5'-UTR binding
h	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN a 201

Chain	Residue
a	CYS23
a	CYS26
a	CYS74
a	CYS77

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN d 201

Chain	Residue
d	CYS21
d	CYS24
d	CYS39
d	CYS42

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN f 500

Chain	Residue
f	CYS126
f	CYS141
f	CYS144
f	CYS121

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG 2 1901

Chain	Residue
2	HOH2026
2	HOH2067
2	HOH2071
2	HOH2076
2	HOH2114
2	HOH2126

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG 2 1902

Chain	Residue
2	HOH2004
2	HOH2008
2	HOH2033
2	HOH2073
2	HOH2096
2	HOH2113

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG 2 1903

Chain	Residue
2	HOH2051
2	HOH2063
2	HOH2081
2	HOH2102
2	HOH2108
C	HOH302

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG 2 1904

Chain	Residue
2	HOH2029
2	HOH2036
2	HOH2061
2	HOH2075
2	HOH2080
2	HOH2092

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG 2 1905

Chain	Residue
2	HOH2012
2	HOH2030
2	HOH2057
2	HOH2069
2	HOH2095
2	HOH2103

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG 2 1906

Chain	Residue
2	HOH2031
2	HOH2041
2	HOH2109
2	HOH2136
2	HOH2138
2	HOH2139

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG 2 1907

Chain	Residue
2	HOH2016
2	HOH2022
2	HOH2042
2	HOH2052
2	HOH2070
2	HOH2123

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG 2 1908

Chain	Residue
2	HOH2019
2	HOH2044
2	HOH2058
2	HOH2078
2	HOH2087
2	HOH2134

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG 2 1909

Chain	Residue
2	HOH2003
2	HOH2054
2	HOH2072
2	HOH2079
2	HOH2111
2	HOH2131

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG 2 1910

Chain	Residue
2	HOH2023
2	HOH2091
2	HOH2093
2	HOH2107
2	HOH2127
2	HOH2130

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG 2 1911

Chain	Residue
2	HOH2011
2	HOH2027
2	HOH2064
2	HOH2124
2	HOH2128
2	HOH2141

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG 2 1912

Chain	Residue
2	HOH2002
2	HOH2025
2	HOH2043
2	HOH2047
2	HOH2115
2	HOH2135

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG 2 1913

Chain	Residue
2	HOH2006
2	HOH2039
2	HOH2074
2	HOH2088
2	HOH2090
2	HOH2133

site_id	BC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG 2 1914

Chain	Residue
2	HOH2007
2	HOH2040
2	HOH2048
2	HOH2068
2	HOH2094
2	HOH2099

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG 2 1915

Chain	Residue
2	HOH2100
2	HOH2110
2	HOH2122
2	HOH2032
2	HOH2060
2	HOH2086

site_id	CC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG 2 1916

Chain	Residue
2	G1354
2	HOH2013
2	HOH2046
2	HOH2077
2	HOH2129
2	HOH2137
C	HOH301

site_id	CC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG 2 1917

Chain	Residue
2	HOH2055
2	HOH2082
2	HOH2084
2	HOH2089
2	HOH2112
2	HOH2125

site_id	CC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG 2 1918

Chain	Residue
2	G1071
2	HOH2035
2	HOH2037
2	HOH2050
2	HOH2062
2	HOH2105
2	HOH2106

site_id	CC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG 2 1919

Chain	Residue
2	HOH2038
2	HOH2085
2	HOH2101
2	HOH2120
2	HOH2121
2	HOH2140

site_id	CC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MG 2 1920

Chain	Residue
2	G370
2	A389
2	HOH2024
2	HOH2028
2	HOH2034
2	HOH2049
2	HOH2056
2	HOH2104

site_id	CC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG 2 1921

Chain	Residue
2	A149
2	HOH2010
2	HOH2014
2	HOH2065
2	HOH2066
2	HOH2097
2	HOH2098

site_id	CC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG 2 1922

Chain	Residue
2	HOH2020
2	HOH2053
2	HOH2083
2	HOH2119
2	HOH2132
e	HOH101

site_id	CC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG 2 1923

Chain	Residue
2	G1176
2	HOH2018
2	HOH2021
2	HOH2045
2	HOH2116
2	HOH2117
2	HOH2118

site_id	CC9
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MG 2 1924

Chain	Residue
2	A587
2	G589
2	U591
2	HOH2001
2	HOH2005
2	HOH2009
2	HOH2015
2	HOH2017
2	HOH2059

site_id	DC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1925

Chain	Residue
2	G999

site_id	DC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 1926

Chain	Residue
2	A449
2	C450
I	LYS23

site_id	DC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 1927

Chain	Residue
2	A1832
2	G1837
2	U1840

site_id	DC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 1928

Chain	Residue
2	G419
2	A654
2	G656

site_id	DC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1929

Chain	Residue
2	G684
2	A685

site_id	DC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 1930

Chain	Residue
2	G601
2	A604
2	A605

site_id	DC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1931

Chain	Residue
2	G94

site_id	DC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1932

Chain	Residue
2	C663
2	G1157

site_id	DC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1933

Chain	Residue
2	G16

site_id	EC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1934

Chain	Residue
2	A92
2	G451

site_id	EC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1935

Chain	Residue
2	A1082

site_id	EC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1936

Chain	Residue
2	U1360

site_id	EC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1937

Chain	Residue
2	G1166
2	G1167

site_id	EC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 1938

Chain	Residue
2	G1693
2	U1694
2	G1862

site_id	EC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1939

Chain	Residue
2	C450

site_id	EC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1940

Chain	Residue
2	C676
2	U1025

site_id	EC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1941

Chain	Residue
2	U1838
2	U1839

site_id	EC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1942

Chain	Residue
2	A653

site_id	FC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1943

Chain	Residue
2	A1036
2	U1072

site_id	FC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1944

Chain	Residue
2	G986

site_id	FC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1945

Chain	Residue
2	A1028
2	G1029

site_id	FC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1946

Chain	Residue
2	C35
2	C579

site_id	FC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1947

Chain	Residue
2	A99

site_id	FC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 2 1948

Chain	Residue
2	A99
2	U100
2	A408
2	C409

site_id	FC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 2 1949

Chain	Residue
2	U1830
2	A1831
2	A1832
2	G1837

site_id	FC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1950

Chain	Residue
2	G1387

site_id	FC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1951

Chain	Residue
2	C472

site_id	GC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 1952

Chain	Residue
2	G90
2	G444
2	G446

site_id	GC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1953

Chain	Residue
2	A672
2	C674

site_id	GC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 2 1954

Chain	Residue
2	C492
2	U495
2	C496
2	G506

site_id	GC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 2 1955

Chain	Residue
2	U667
2	A668
2	A669
2	A670

site_id	GC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1956

Chain	Residue
2	A668

site_id	GC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1957

Chain	Residue
2	A672

site_id	GC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1958

Chain	Residue
2	G41
2	U97

site_id	GC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 1959

Chain	Residue
2	G411
2	A426
2	U427

site_id	GC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1961

Chain	Residue
2	A1035

site_id	HC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 2 1962

Chain	Residue
2	U1101
2	G1102
2	G1130
2	G1131

site_id	HC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1963

Chain	Residue
2	A599
2	G600

site_id	HC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1964

Chain	Residue
2	G620

site_id	HC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1965

Chain	Residue
2	U647

site_id	HC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1966

Chain	Residue
2	G644

site_id	HC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1967

Chain	Residue
2	U375
2	G385

site_id	HC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1968

Chain	Residue
2	A679

site_id	HC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1969

Chain	Residue
2	G410

site_id	HC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1970

Chain	Residue
2	A27

site_id	IC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1971

Chain	Residue
2	C48
2	A473

site_id	IC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 2 1972

Chain	Residue
2	G1736
2	G1737
2	G1796
2	U1797

site_id	IC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1973

Chain	Residue
2	G153

site_id	IC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1974

Chain	Residue
2	G504

site_id	IC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1975

Chain	Residue
2	A1697

site_id	IC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1976

Chain	Residue
2	A508
2	G509

site_id	IC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1977

Chain	Residue
2	C1026

site_id	IC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 2 1978

Chain	Residue
2	C1682
2	C1684
2	U1685
2	G1686

site_id	IC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1979

Chain	Residue
2	A920

site_id	JC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1980

Chain	Residue
2	U28
2	A516

site_id	JC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1982

Chain	Residue
2	G1792

site_id	JC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 1984

Chain	Residue
2	G1171
2	U1186
2	G1187

site_id	JC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1985

Chain	Residue
2	C117
2	C118

site_id	JC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 1986

Chain	Residue
2	A42
2	U43
2	A46

site_id	JC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1987

Chain	Residue
2	U1061

site_id	JC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 1988

Chain	Residue
2	U815
2	A816
2	G817

site_id	JC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1989

Chain	Residue
2	G7
2	G16

site_id	JC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 1990

Chain	Residue
2	G513
2	U514
2	G515

site_id	KC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 1992

Chain	Residue
2	A564
2	U580

site_id	KC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1993

Chain	Residue
2	A655

site_id	KC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1994

Chain	Residue
2	G602

site_id	KC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1995

Chain	Residue
2	G1033

site_id	KC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1996

Chain	Residue
2	A854

site_id	KC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 2 1998

Chain	Residue
2	G291

Functional Information from PROSITE/UniProt

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsMMmhgrnnGKKlmtvrIVkhA

Chain	Residue	Details
F	GLU70-ALA96

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GfiVLTTSaGIMdheeAR

Chain	Residue	Details
W	GLY100-ARG117

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GMkIgrieDvTPiPSD

Chain	Residue	Details
O	LEU116-ASP138

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR

Chain	Residue	Details
X	LYS60-ARG67

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVtVgEcRPLS

Chain	Residue	Details
L	GLY123-SER135

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKtfnqveIkpemIGhyLGEFsiT

Chain	Residue	Details
P	ASN98-THR122

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvAQiyAirqSiSKAL

Chain	Residue	Details
Q	GLY74-LEU92

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AkekNLkvkGPVrMPT

Chain	Residue	Details
U	ALA43-THR58

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY

Chain	Residue	Details
N	VAL98-TYR128

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. RvCsnrhglirkyg.LNMCRqCFR

Chain	Residue	Details
d	ARG22-ARG44

site_id	PS00528
Number of Residues	15
Details	RIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRVAaPkhWmLdK

Chain	Residue	Details
E	HIS8-LYS22

site_id	PS00529
Number of Residues	23
Details	RIBOSOMAL_S24E Ribosomal protein S24e signature. FGggKTtGFGmIYDSldyakknE

Chain	Residue	Details
Y	PHE64-GLU86

site_id	PS00548
Number of Residues	37
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. AKsmkfvdGlMihSgdpVnyyVDtavrhvlLrqGvlG

Chain	Residue	Details
D	ALA147-GLY183

site_id	PS00578
Number of Residues	12
Details	RIBOSOMAL_S6E Ribosomal protein S6e signature. ISGGnDkqGfPM

Chain	Residue	Details
G	ILE52-MET63

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAfvAIGDyn.GhVGlGvkcsk.EVat.AI

Chain	Residue	Details
C	GLY119-ILE151

site_id	PS00628
Number of Residues	20
Details	RIBOSOMAL_S19E Ribosomal protein S19e signature. PshfsrgSksVaRrVLQaLE

Chain	Residue	Details
T	PRO89-GLU108

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVFKlglAkSihhARvLI

Chain	Residue	Details
J	LEU106-ILE130

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHfwGlrVRGQ

Chain	Residue	Details
S	ARG121-GLN134

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. ALSGswDgTLRLWDL

Chain	Residue	Details
g	ALA78-LEU92
g	ILE120-THR134
g	ILE165-LEU179
g	CYS207-LEU221

site_id	PS00712
Number of Residues	16
Details	RIBOSOMAL_S17E Ribosomal protein S17e signature. IpSKkLRNkIAGYvTH

Chain	Residue	Details
R	ILE41-HIS56

site_id	PS00948
Number of Residues	14
Details	RIBOSOMAL_S7E Ribosomal protein S7e signature. RLvRELEKKFSgKH

Chain	Residue	Details
H	ARG78-HIS91

site_id	PS00961
Number of Residues	9
Details	RIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL

Chain	Residue	Details
c	GLU60-LEU68

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. VlKFLAAGTHLG

Chain	Residue	Details
A	VAL15-GLY26

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PrlLVVtDpraDhqpLtEasyvNLP

Chain	Residue	Details
A	PRO119-PRO143

site_id	PS00996
Number of Residues	9
Details	RIBOSOMAL_S21E Ribosomal protein S21e signature. LYVPRKCSA

Chain	Residue	Details
V	LEU11-ALA19

site_id	PS01168
Number of Residues	33
Details	RIBOSOMAL_S27E Ribosomal protein S27e signature. KCpgCykittvFShAqtvvlCvgCStvLcqPtG

Chain	Residue	Details
b	LYS36-GLY68

site_id	PS01189
Number of Residues	19
Details	RIBOSOMAL_S12E Ribosomal protein S12e signature. ALQevLktAlihDGLarGI

Chain	Residue	Details
M	ALA17-ILE35

site_id	PS01191
Number of Residues	13
Details	RIBOSOMAL_S3AE Ribosomal protein S3Ae signature. LkGRVfEvSLaDL

Chain	Residue	Details
B	LEU62-LEU74

site_id	PS01193
Number of Residues	20
Details	RIBOSOMAL_S8E Ribosomal protein S8e signature. RrkTGGkrkpy.HkKrKyELG

Chain	Residue	Details
I	ARG11-GLY30

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	23
Details	ZN_FING: C4-type

Chain	Residue	Details
f	CYS121-CYS144
B	LYS249

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0007744\|PubMed:19608861

Chain	Residue	Details
f	LYS104
f	LYS113
b	CYS56
b	CYS59

site_id	SWS_FT_FI3
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:36638793

Chain	Residue	Details
f	LYS107
g	THR10
g	THR96

site_id	SWS_FT_FI4
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:32129764, ECO:0000269\|PubMed:36638793

Chain	Residue	Details
B	SER236
f	LYS113
S	LYS106
O	LYS106

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250\|UniProtKB:P97351

Chain	Residue	Details
B	SER237
L	SER110
K	LYS139

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphotyrosine => ECO:0007744\|PubMed:15592455

Chain	Residue	Details
B	TYR256
N	LYS43
D	ARG67

site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:16964243, ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:18691976, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
B	SER263
U	LYS8

site_id	SWS_FT_FI8
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
B	LYS34
C	LYS275

site_id	SWS_FT_FI9
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744\|PubMed:25755297, ECO:0007744\|PubMed:28112733

Chain	Residue	Details
g	THR277
B	LYS249

site_id	SWS_FT_FI10
Number of Residues	2
Details	MOD_RES: Phosphoserine; by viral VacV B1 kinase => ECO:0000269\|PubMed:28636603

Chain	Residue	Details
g	SER278
g	SER279

site_id	SWS_FT_FI11
Number of Residues	1
Details	MOD_RES: Phosphothreonine; by CDK1 and PKC/PRKCD => ECO:0000269\|PubMed:19059439, ECO:0000269\|PubMed:21871177, ECO:0000269\|Ref.12, ECO:0007744\|PubMed:16964243, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
D	THR221

site_id	SWS_FT_FI12
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:16807684

Chain	Residue	Details
D	SER224

site_id	SWS_FT_FI13
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18691976, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
D	THR242

site_id	SWS_FT_FI14
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)

Chain	Residue	Details
D	LYS90
D	LYS202

site_id	SWS_FT_FI15
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:25114211, ECO:0007744\|PubMed:28112733

Chain	Residue	Details
D	LYS230

site_id	SWS_FT_FI16
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269\|PubMed:28065601, ECO:0000269\|PubMed:28132843, ECO:0000269\|PubMed:31981475, ECO:0000269\|PubMed:32011234, ECO:0000269\|PubMed:34348161, ECO:0000269\|PubMed:34469731

Chain	Residue	Details
D	LYS214

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)