5A1T
Trichomonas vaginalis lactate dehydrogenase in complex with NADH and oxamate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0006108 | biological_process | malate metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016615 | molecular_function | malate dehydrogenase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
| A | 0030060 | molecular_function | L-malate dehydrogenase (NAD+) activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0006108 | biological_process | malate metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016615 | molecular_function | malate dehydrogenase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0019752 | biological_process | carboxylic acid metabolic process |
| B | 0030060 | molecular_function | L-malate dehydrogenase (NAD+) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 32 |
| Details | BINDING SITE FOR RESIDUE NAI A 345 |
| Chain | Residue |
| A | GLY11 |
| A | ALA87 |
| A | SER88 |
| A | ILE107 |
| A | ILE128 |
| A | ASN130 |
| A | ASP132 |
| A | LEU157 |
| A | HIS186 |
| A | SER240 |
| A | PRO244 |
| A | GLY14 |
| A | OXM346 |
| A | HOH2004 |
| A | HOH2055 |
| A | HOH2104 |
| A | HOH2105 |
| A | HOH2108 |
| A | HOH2182 |
| A | HOH2202 |
| A | HOH2301 |
| A | HOH2302 |
| A | GLN15 |
| A | HOH2396 |
| A | HOH2397 |
| A | HOH2399 |
| A | ILE16 |
| A | ASP41 |
| A | ILE42 |
| A | ALA45 |
| A | ARG48 |
| A | VAL86 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE OXM A 346 |
| Chain | Residue |
| A | ARG97 |
| A | ASN130 |
| A | LEU157 |
| A | ARG161 |
| A | HIS186 |
| A | ALA229 |
| A | SER240 |
| A | NAI345 |
| A | HOH2182 |
| A | HOH2286 |
| site_id | AC3 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE NAI B 345 |
| Chain | Residue |
| B | GLY11 |
| B | ALA13 |
| B | GLY14 |
| B | GLN15 |
| B | ILE16 |
| B | ASP41 |
| B | ILE42 |
| B | ALA45 |
| B | VAL86 |
| B | ALA87 |
| B | SER88 |
| B | ILE107 |
| B | ILE128 |
| B | GLY129 |
| B | ASN130 |
| B | ASP132 |
| B | LEU157 |
| B | HIS186 |
| B | SER240 |
| B | PRO244 |
| B | OXM346 |
| B | HOH2005 |
| B | HOH2009 |
| B | HOH2086 |
| B | HOH2088 |
| B | HOH2124 |
| B | HOH2138 |
| B | HOH2201 |
| B | HOH2242 |
| B | HOH2243 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE OXM B 346 |
| Chain | Residue |
| B | ARG97 |
| B | ASN130 |
| B | LEU157 |
| B | ARG161 |
| B | HIS186 |
| B | ALA229 |
| B | THR239 |
| B | SER240 |
| B | NAI345 |
| B | HOH2124 |
| B | HOH2190 |
