4ZYP

Crystal Structure of Motavizumab and Quaternary-Specific RSV-Neutralizing Human Antibody AM14 in Complex with Prefusion RSV F Glycoprotein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0019064	biological_process	fusion of virus membrane with host plasma membrane
B	0019064	biological_process	fusion of virus membrane with host plasma membrane
C	0019064	biological_process	fusion of virus membrane with host plasma membrane

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
G	TYR192-HIS198
F	TYR194-HIS200
L	TYR192-HIS198
J	TYR194-HIS200

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	SITE: Cleavage; by host furin-like protease => ECO:0000269|PubMed:11493675, ECO:0000269|PubMed:12127793

Chain	Residue	Details
A	ARG136
B	ARG136
C	ARG136

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site_id	SWS_FT_FI2
Number of Residues	3
Details	SITE: Cleavage; by host furin-like protease => ECO:0000269|PubMed:11369882, ECO:0000269|PubMed:12127793

Chain	Residue	Details
A	GLU163
B	GLU163
C	GLU163

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site_id	SWS_FT_FI3
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:21586636

Chain	Residue	Details
A	ASN27
B	ASN27
C	ASN27

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site_id	SWS_FT_FI4
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:21586636, ECO:0000269|PubMed:28469033

Chain	Residue	Details
A	ASN70
B	ASN70
C	ASN70

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site_id	SWS_FT_FI5
Number of Residues	9
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255

Chain	Residue	Details
A	GLY143
A	ALA147
A	ALA153
B	GLY143
B	ALA147
B	ALA153
C	GLY143
C	ALA147
C	ALA153

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site_id	SWS_FT_FI6
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:21586636, ECO:0000269|PubMed:24179220

Chain	Residue	Details
A	GLY527
B	GLY527
C	GLY527

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