4ZVE
Crystal structure of GGDEF domain of the E. coli DosC - form I (apo-form)
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue CIT A 501 |
| Chain | Residue |
| A | THR323 |
| A | HOH621 |
| A | HOH649 |
| A | HOH656 |
| A | HOH658 |
| A | HOH686 |
| A | HOH756 |
| A | LYS336 |
| A | PHE337 |
| A | LYS338 |
| A | GLU339 |
| A | ASP376 |
| A | ARG450 |
| A | HOH601 |
| A | HOH620 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | ARG307 |
| A | PHE308 |
| A | ARG452 |
| A | VAL453 |
| A | HOH639 |
| A | HOH678 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | ARG307 |
| A | ASP342 |
| A | GLY345 |
| A | ARG448 |
| A | GLY449 |
| A | ARG450 |
| A | ASN451 |
| A | ARG452 |
| A | HOH637 |
| A | HOH692 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255 |
| Chain | Residue | Details |
| A | ASP376 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP350 | |
| A | ASP376 | |
| A | ASP333 | |
| A | ASN341 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Transition state stabilizer => ECO:0000255 |
| Chain | Residue | Details |
| A | LYS338 |
