4ZTX
Neurospora crassa cobalamin-independent methionine synthase complexed with Zn2+
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003871 | molecular_function | 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009086 | biological_process | methionine biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019280 | biological_process | L-methionine biosynthetic process from L-homoserine via O-acetyl-L-homoserine |
| A | 0032259 | biological_process | methylation |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0071265 | biological_process | L-methionine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1000 |
| Chain | Residue |
| A | HIS652 |
| A | CYS654 |
| A | GLU676 |
| A | CYS737 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue NO3 A 3000 |
| Chain | Residue |
| A | LEU477 |
| A | LYS480 |
| A | ILE481 |
| A | LYS748 |
| A | ALA376 |
| A | VAL377 |
| A | LYS378 |
| A | ALA379 |
| A | GLU380 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 3001 |
| Chain | Residue |
| A | LEU36 |
| A | GLN74 |
| A | PRO90 |
| A | LEU91 |
| A | ARG144 |
| A | HOH5203 |
| A | HOH5214 |
| A | HOH5476 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 3002 |
| Chain | Residue |
| A | ASN120 |
| A | ARG570 |
| A | TRP571 |
| A | SER572 |
| A | PHE573 |
| A | PRO574 |
| A | HOH5072 |
| A | HOH5530 |
| A | HOH5676 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 3003 |
| Chain | Residue |
| A | TYR25 |
| A | ASP28 |
| A | ASP92 |
| A | LYS395 |
| A | HOH5327 |
| A | HOH5473 |
| A | HOH5596 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 3004 |
| Chain | Residue |
| A | VAL701 |
| A | ASP703 |
| A | ARG708 |
| A | GLU714 |
| A | HOH5689 |
