4ZR0
Full length scs7p (only hydroxylase domain visible)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000038 | biological_process | very long-chain fatty acid metabolic process |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0006673 | biological_process | inositol phosphoceramide metabolic process |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0008610 | biological_process | lipid biosynthetic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0046513 | biological_process | ceramide biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0080132 | molecular_function | fatty acid 2-hydroxylase activity |
| A | 0102771 | molecular_function | dihydroceramide fatty acyl 2-hydroxylase activity |
| A | 0102772 | molecular_function | sphingolipid C4-monooxygenase activity |
| A | 0120521 | molecular_function | 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase activity |
| B | 0000038 | biological_process | very long-chain fatty acid metabolic process |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0005783 | cellular_component | endoplasmic reticulum |
| B | 0005789 | cellular_component | endoplasmic reticulum membrane |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0006673 | biological_process | inositol phosphoceramide metabolic process |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0008610 | biological_process | lipid biosynthetic process |
| B | 0016020 | cellular_component | membrane |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0020037 | molecular_function | heme binding |
| B | 0046513 | biological_process | ceramide biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0080132 | molecular_function | fatty acid 2-hydroxylase activity |
| B | 0102771 | molecular_function | dihydroceramide fatty acyl 2-hydroxylase activity |
| B | 0102772 | molecular_function | sphingolipid C4-monooxygenase activity |
| B | 0120521 | molecular_function | 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 401 |
| Chain | Residue |
| A | HIS271 |
| A | HIS326 |
| A | HIS330 |
| A | HIS345 |
| A | HIS349 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 402 |
| Chain | Residue |
| A | HIS348 |
| A | HIS244 |
| A | HIS249 |
| A | HIS268 |
| A | HIS272 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue ZN B 401 |
| Chain | Residue |
| B | HIS271 |
| B | HIS326 |
| B | HIS330 |
| B | HIS345 |
| B | HIS349 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue ZN B 402 |
| Chain | Residue |
| B | HIS244 |
| B | HIS249 |
| B | HIS268 |
| B | HIS272 |
| B | HIS348 |
Functional Information from PROSITE/UniProt
| site_id | PS00191 |
| Number of Residues | 8 |
| Details | CYTOCHROME_B5_1 Cytochrome b5 family, heme-binding domain signature. FLSEHPGG |
| Chain | Residue | Details |
| A | PHE41-GLY48 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 36 |
| Details | Transmembrane: {"description":"Helical; Name=TM1","evidences":[{"source":"PubMed","id":"26515067","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Topological domain: {"description":"Lumenal","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 48 |
| Details | Transmembrane: {"description":"Helical; Name=TM2","evidences":[{"source":"PubMed","id":"26515067","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 129 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 34 |
| Details | Transmembrane: {"description":"Helical; Name=TM3","evidences":[{"source":"PubMed","id":"26515067","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 46 |
| Details | Transmembrane: {"description":"Helical; Name=TM4","evidences":[{"source":"PubMed","id":"26515067","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26515067","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
