4ZKF
Crystal structure of human phosphodiesterase 12
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 701 |
| Chain | Residue |
| A | GLU351 |
| A | HOH823 |
| A | HOH865 |
| A | HOH881 |
| A | HOH892 |
| A | HOH1145 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 702 |
| Chain | Residue |
| A | HOH865 |
| A | HIS456 |
| A | ASP496 |
| A | ASN498 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000250|UniProtKB:Q96LI5 |
| Chain | Residue | Details |
| A | ASP496 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:26055709, ECO:0000269|Ref.16, ECO:0007744|PDB:4Z0V, ECO:0007744|PDB:4ZKF |
| Chain | Residue | Details |
| A | GLU351 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|Ref.16, ECO:0007744|PDB:4ZKF |
| Chain | Residue | Details |
| A | ASP496 | |
| A | ASN498 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER217 |
