4ZKA
High Resolution Crystal Structure of Fox1 RRM
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000381 | biological_process | regulation of alternative mRNA splicing, via spliceosome |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0007399 | biological_process | nervous system development |
| B | 0000381 | biological_process | regulation of alternative mRNA splicing, via spliceosome |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0007399 | biological_process | nervous system development |
| C | 0000381 | biological_process | regulation of alternative mRNA splicing, via spliceosome |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0003723 | molecular_function | RNA binding |
| C | 0007399 | biological_process | nervous system development |
| D | 0000381 | biological_process | regulation of alternative mRNA splicing, via spliceosome |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0003723 | molecular_function | RNA binding |
| D | 0007399 | biological_process | nervous system development |
| E | 0000381 | biological_process | regulation of alternative mRNA splicing, via spliceosome |
| E | 0003676 | molecular_function | nucleic acid binding |
| E | 0003723 | molecular_function | RNA binding |
| E | 0007399 | biological_process | nervous system development |
| F | 0000381 | biological_process | regulation of alternative mRNA splicing, via spliceosome |
| F | 0003676 | molecular_function | nucleic acid binding |
| F | 0003723 | molecular_function | RNA binding |
| F | 0007399 | biological_process | nervous system development |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 201 |
| Chain | Residue |
| A | PHE18 |
| A | ARG21 |
| A | GLY46 |
| A | SER47 |
| A | HOH303 |
| B | ARG63 |
| B | GLU66 |
| B | LYS67 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue MES A 202 |
| Chain | Residue |
| A | GLY75 |
| A | ARG76 |
| B | GLY30 |
| B | GLN31 |
| B | PHE32 |
| B | ASP60 |
| B | SO4201 |
| B | HOH361 |
| A | GLU74 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 B 201 |
| Chain | Residue |
| A | PRO17 |
| A | PHE18 |
| A | ARG19 |
| A | ARG76 |
| A | MES202 |
| A | HOH322 |
| B | ARG63 |
| B | HOH325 |
| B | HOH334 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 B 202 |
| Chain | Residue |
| B | PHE18 |
| B | ARG19 |
| B | ARG21 |
| B | GLY46 |
| B | SER47 |
| B | HOH301 |
| B | HOH311 |
| C | GLU74 |
| C | GLY75 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 203 |
| Chain | Residue |
| B | ARG45 |
| B | HOH303 |
| D | LYS34 |
| D | GLU56 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue MES C 201 |
| Chain | Residue |
| B | LYS5 |
| C | LYS9 |
| C | ASP62 |
| C | ASN82 |
| C | HOH301 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 D 201 |
| Chain | Residue |
| D | PHE18 |
| D | ARG21 |
| D | GLY46 |
| D | SER47 |
| D | HOH306 |
| E | ARG63 |
| E | GLU66 |
| E | LYS67 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue PG4 D 202 |
| Chain | Residue |
| D | ASN15 |
| D | GLY75 |
| D | ARG76 |
| E | GLN31 |
| E | PHE32 |
| E | ASP60 |
| E | SO4201 |
| E | HOH347 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 E 201 |
| Chain | Residue |
| D | PRO17 |
| D | PHE18 |
| D | ARG19 |
| D | ARG76 |
| D | PG4202 |
| D | HOH305 |
| D | HOH319 |
| E | ARG63 |
| E | HOH324 |
| E | HOH333 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue MES E 202 |
| Chain | Residue |
| E | PRO17 |
| E | PHE18 |
| E | ARG19 |
| E | ARG76 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 F 201 |
| Chain | Residue |
| F | PRO17 |
| F | PHE18 |
| F | ARG76 |
| F | HOH306 |
| F | HOH308 |
| F | HOH319 |
| site_id | AD3 |
| Number of Residues | 8 |
| Details | binding site for residue MES F 202 |
| Chain | Residue |
| E | HOH353 |
| F | PHE18 |
| F | ARG45 |
| F | HOH301 |
| F | HOH310 |
| F | HOH311 |
| F | HOH314 |
| F | HOH341 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 228 |
| Details | Domain: {"description":"RRM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00176","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 42 |
| Details | Site: {"description":"Interaction with RNA"} |
| Chain | Residue | Details |
