4ZIU

Crystal structure of native alpha-2-macroglobulin from Escherichia coli spanning the residues from domain MG7 to the C-terminus.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005615	cellular_component	extracellular space

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue NI A 1701

Chain	Residue
A	GLU1329
A	HIS1333
A	GLU1606
A	GOL1704

---

site_id	AC2
Number of Residues	4
Details	binding site for residue NI A 1702

Chain	Residue
A	GLY1015
A	HIS1016
A	ASP1114
A	HIS1116

---

site_id	AC3
Number of Residues	4
Details	binding site for residue GOL A 1703

Chain	Residue
A	VAL1123
A	ARG1124
A	ASP1595
A	TYR1093

---

site_id	AC4
Number of Residues	6
Details	binding site for residue GOL A 1704

Chain	Residue
A	GLU1329
A	GLU1332
A	HIS1333
A	SER1539
A	GLU1606
A	NI1701

---

site_id	AC5
Number of Residues	2
Details	binding site for residue GOL A 1705

Chain	Residue
A	HIS1510
A	HOH1808

---

site_id	AC6
Number of Residues	2
Details	binding site for residue GOL A 1706

Chain	Residue
A	GLN1585
A	ALA1586

---

site_id	AC7
Number of Residues	6
Details	binding site for residue GOL A 1707

Chain	Residue
A	MET1017
A	MET1017
A	ALA1018
A	VAL1112
A	VAL1112
A	ASP1114

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	30
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Cross-link: {"description":"Isoglutamyl cysteine thioester (Cys-Gln)","evidences":[{"source":"PubMed","id":"18697741","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---