4ZIQ

Crystal structure of trypsin activated alpha-2-macroglobulin from Escherichia coli.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004866	molecular_function	endopeptidase inhibitor activity
A	0005615	cellular_component	extracellular space
A	0005886	cellular_component	plasma membrane
A	0006952	biological_process	defense response
A	0030414	molecular_function	peptidase inhibitor activity
A	0042803	molecular_function	protein homodimerization activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue GOL A 1701

Chain	Residue
A	ILE1377
A	GLY1380
A	ASP1381
A	TYR1382

---

site_id	AC2
Number of Residues	1
Details	binding site for residue CL A 1703

Chain	Residue
A	GLU594

---

site_id	AC3
Number of Residues	1
Details	binding site for residue CL A 1704

Chain	Residue
A	ARG1436

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	CROSSLNK: Isoglutamyl cysteine thioester (Cys-Gln) => ECO:0000269|PubMed:18697741

Chain	Residue	Details
A	CYS1187
A	GLN1190

---