Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0008289 | molecular_function | lipid binding |
| A | 0015485 | molecular_function | cholesterol binding |
| A | 0020002 | cellular_component | host cell plasma membrane |
| A | 0031640 | biological_process | killing of cells of another organism |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0090729 | molecular_function | toxin activity |
| A | 0141060 | biological_process | disruption of anatomical structure in another organism |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | TYR71 |
| A | ALA91 |
| A | VAL92 |
| A | ARG94 |
| A | PRO118 |
| A | ARG208 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | HIS-2 |
| A | GLN215 |
| A | ASP216 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | THR458 |
| A | THR459 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | ASN209 |
| A | ASP212 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | TYR15 |
| A | LYS17 |
| A | LYS18 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue PEG A 506 |
| Chain | Residue |
| A | HIS-1 |
| A | TRP456 |
| A | GLY457 |
| A | TYR461 |
| A | GLN463 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 507 |
| Chain | Residue |
| A | ASP403 |
| A | AUC508 |
| A | AUC509 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue AUC A 508 |
| Chain | Residue |
| A | CYS428 |
| A | GLY430 |
| A | PEG507 |
| A | AUC509 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue AUC A 509 |
| Chain | Residue |
| A | CYS428 |
| A | TYR461 |
| A | PEG507 |
| A | AUC508 |
Functional Information from PROSITE/UniProt
| site_id | PS00481 |
| Number of Residues | 12 |
| Details | THIOL_CYTOLYSINS Thiol-activated cytolysins signature. RECTGLaWEWWR |
| Chain | Residue | Details |
| A | ARG426-ARG437 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 43 |
| Details | Transmembrane: {"description":"Beta stranded","evidences":[{"source":"PubMed","id":"28323617","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5LY6","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Motif: {"description":"Conserved undecapeptide","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Motif: {"description":"Cholesterol binding","evidences":[{"source":"PubMed","id":"20145114","evidenceCode":"ECO:0000269"}]} |
