4ZFG
Dual-specificity Fab 5A12 in complex with Angiopoietin 2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0007596 | biological_process | blood coagulation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 601 |
| Chain | Residue |
| A | ASP429 |
| A | ASP431 |
| A | CYS433 |
| A | CYS435 |
| A | HOH707 |
| A | HOH730 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 602 |
| Chain | Residue |
| A | GLY481 |
| A | HOH702 |
| A | HOH783 |
| L | PHE27 |
| L | SER30 |
| L | HOH303 |
| A | LYS473 |
| A | TYR475 |
| A | SER480 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 603 |
| Chain | Residue |
| A | ARG337 |
| A | PHE346 |
| A | GLY347 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 604 |
| Chain | Residue |
| A | GLY405 |
| A | LEU406 |
| L | LYS145 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 H 301 |
| Chain | Residue |
| H | ARG19 |
| H | LYS75 |
| H | TYR79 |
| H | HOH413 |
| H | HOH431 |
| H | HOH468 |
| H | HOH500 |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| H | TYR194-HIS200 | |
| L | TYR192-HIS198 |
| site_id | PS00514 |
| Number of Residues | 13 |
| Details | FIBRINOGEN_C_1 Fibrinogen C-terminal domain signature. WWFdaCgpSnlNG |
| Chain | Residue | Details |
| A | TRP445-GLY457 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15893672","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16732286","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1Z3U","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
