4ZEQ

Crystal Structure of human BFL-1 in complex with tBid BH3 peptide, Northeast Structural Genomics Consortium Target HX9247

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0042981	biological_process	regulation of apoptotic process
A	0043066	biological_process	negative regulation of apoptotic process
B	0005737	cellular_component	cytoplasm
B	0042981	biological_process	regulation of apoptotic process
B	0043065	biological_process	positive regulation of apoptotic process

Functional Information from PROSITE/UniProt

site_id	PS01080
Number of Residues	20
Details	BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. EFeDGiiNWGRIVTIFaFEG

Chain	Residue	Details
A	GLU78-GLY97

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site_id	PS01258
Number of Residues	12
Details	BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIrqnGGWEnGF

Chain	Residue	Details
A	TRP133-PHE144

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site_id	PS01259
Number of Residues	15
Details	BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. IarhLAqVGDSMDRS

Chain	Residue	Details
B	ILE86-SER100

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	Motif: {"description":"BH1"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	15
Details	Motif: {"description":"BH2"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	14
Details	Motif: {"description":"BH3","evidences":[{"source":"UniProtKB","id":"P70444","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Site: {"description":"Cleavage","evidences":[{"source":"UniProtKB","id":"P70444","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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