4ZD5
Catalytic domain of Sst2 F403A mutant
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0016579 | biological_process | protein deubiquitination |
| A | 0061578 | molecular_function | K63-linked deubiquitinase activity |
| A | 0070536 | biological_process | protein K63-linked deubiquitination |
| A | 0140492 | molecular_function | metal-dependent deubiquitinase activity |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0016579 | biological_process | protein deubiquitination |
| B | 0061578 | molecular_function | K63-linked deubiquitinase activity |
| B | 0070536 | biological_process | protein K63-linked deubiquitination |
| B | 0140492 | molecular_function | metal-dependent deubiquitinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 501 |
| Chain | Residue |
| A | HIS341 |
| A | HIS343 |
| A | ASP354 |
| A | HOH608 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 502 |
| Chain | Residue |
| A | HIS356 |
| A | CYS397 |
| A | HIS404 |
| A | HIS406 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | LEU260 |
| A | VAL414 |
| A | ALA415 |
| A | GLY418 |
| A | HIS419 |
| A | HOH631 |
| A | HOH635 |
| A | ALA252 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | GLU286 |
| A | ASP315 |
| A | THR316 |
| A | CYS317 |
| A | TRP339 |
| A | HIS341 |
| A | VAL353 |
| A | ASP354 |
| A | THR357 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | CYS288 |
| A | GLY318 |
| A | THR319 |
| A | TYR361 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 501 |
| Chain | Residue |
| B | HIS356 |
| B | CYS397 |
| B | HIS404 |
| B | HIS406 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 502 |
| Chain | Residue |
| B | HIS341 |
| B | HIS343 |
| B | ASP354 |
| B | HOH603 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| B | ILE382 |
| B | VAL414 |
| B | ALA415 |
| B | GLN416 |
| B | GLU422 |
| B | HOH605 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01182 |
| Chain | Residue | Details |
| A | HIS341 | |
| A | HIS343 | |
| A | ASP354 | |
| B | HIS341 | |
| B | HIS343 | |
| B | ASP354 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS356 | |
| A | CYS397 | |
| A | HIS404 | |
| A | HIS406 | |
| B | HIS356 | |
| B | CYS397 | |
| B | HIS404 | |
| B | HIS406 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Indirect zinc-binding => ECO:0000250 |
| Chain | Residue | Details |
| A | GLU286 | |
| B | GLU286 |
