4Z7Y

diphosphomevalonate decarboxylase from the Sulfolobus solfataricus, space group P21

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004163	molecular_function	diphosphomevalonate decarboxylase activity
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0006629	biological_process	lipid metabolic process
A	0008299	biological_process	isoprenoid biosynthetic process
A	0016829	molecular_function	lyase activity
A	0016831	molecular_function	carboxy-lyase activity
A	0019287	biological_process	isopentenyl diphosphate biosynthetic process, mevalonate pathway
B	0000166	molecular_function	nucleotide binding
B	0004163	molecular_function	diphosphomevalonate decarboxylase activity
B	0005524	molecular_function	ATP binding
B	0005829	cellular_component	cytosol
B	0006629	biological_process	lipid metabolic process
B	0008299	biological_process	isoprenoid biosynthetic process
B	0016829	molecular_function	lyase activity
B	0016831	molecular_function	carboxy-lyase activity
B	0019287	biological_process	isopentenyl diphosphate biosynthetic process, mevalonate pathway
C	0000166	molecular_function	nucleotide binding
C	0004163	molecular_function	diphosphomevalonate decarboxylase activity
C	0005524	molecular_function	ATP binding
C	0005829	cellular_component	cytosol
C	0006629	biological_process	lipid metabolic process
C	0008299	biological_process	isoprenoid biosynthetic process
C	0016829	molecular_function	lyase activity
C	0016831	molecular_function	carboxy-lyase activity
C	0019287	biological_process	isopentenyl diphosphate biosynthetic process, mevalonate pathway
D	0000166	molecular_function	nucleotide binding
D	0004163	molecular_function	diphosphomevalonate decarboxylase activity
D	0005524	molecular_function	ATP binding
D	0005829	cellular_component	cytosol
D	0006629	biological_process	lipid metabolic process
D	0008299	biological_process	isoprenoid biosynthetic process
D	0016829	molecular_function	lyase activity
D	0016831	molecular_function	carboxy-lyase activity
D	0019287	biological_process	isopentenyl diphosphate biosynthetic process, mevalonate pathway
E	0000166	molecular_function	nucleotide binding
E	0004163	molecular_function	diphosphomevalonate decarboxylase activity
E	0005524	molecular_function	ATP binding
E	0005829	cellular_component	cytosol
E	0006629	biological_process	lipid metabolic process
E	0008299	biological_process	isoprenoid biosynthetic process
E	0016829	molecular_function	lyase activity
E	0016831	molecular_function	carboxy-lyase activity
E	0019287	biological_process	isopentenyl diphosphate biosynthetic process, mevalonate pathway
F	0000166	molecular_function	nucleotide binding
F	0004163	molecular_function	diphosphomevalonate decarboxylase activity
F	0005524	molecular_function	ATP binding
F	0005829	cellular_component	cytosol
F	0006629	biological_process	lipid metabolic process
F	0008299	biological_process	isoprenoid biosynthetic process
F	0016829	molecular_function	lyase activity
F	0016831	molecular_function	carboxy-lyase activity
F	0019287	biological_process	isopentenyl diphosphate biosynthetic process, mevalonate pathway

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue SO4 A 401

Chain	Residue
A	GLY148
A	GLY149
A	GLN168
A	HIS172
A	ASP317
A	GLY318

---

site_id	AC2
Number of Residues	7
Details	binding site for residue SO4 B 401

Chain	Residue
B	ARG171
B	HIS172
B	ASP317
B	GLY318
B	GLY148
B	GLY149
B	GLN168

---

site_id	AC3
Number of Residues	5
Details	binding site for residue SO4 C 401

Chain	Residue
C	GLY148
C	GLY149
C	GLN168
C	ARG171
C	HIS172

---

site_id	AC4
Number of Residues	6
Details	binding site for residue SO4 D 401

Chain	Residue
D	GLY148
D	GLY149
D	GLN168
D	HIS172
D	ASP317
D	GLY318

---

site_id	AC5
Number of Residues	6
Details	binding site for residue SO4 E 401

Chain	Residue
E	GLY148
E	GLY149
E	GLN168
E	HIS172
E	ASP317
E	GLY318

---

site_id	AC6
Number of Residues	6
Details	binding site for residue SO4 F 401

Chain	Residue
F	GLY148
F	GLN168
F	ARG171
F	HIS172
F	ASP317
F	GLY318

---

Functional Information from PROSITE/UniProt

site_id	PS00867
Number of Residues	8
Details	CPSASE_2 Carbamoyl-phosphate synthase subdomain signature 2. LLELNLKS

Chain	Residue	Details
A	LEU121-SER128

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	BINDING: BINDING => ECO:0000250|UniProtKB:O23722

Chain	Residue	Details
C	TYR18
C	ARG75
C	SER139
D	TYR18
D	ARG75
D	SER139
E	TYR18
E	ARG75
E	SER139
F	TYR18
F	ARG75
F	SER139
A	TYR18
A	ARG75
A	SER139
B	TYR18
B	ARG75
B	SER139

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