4Z2C

Quinolone(Moxifloxacin)-DNA cleavage complex of gyrase from S. pneumoniae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
A	0005524	molecular_function	ATP binding
A	0006259	biological_process	DNA metabolic process
A	0006265	biological_process	DNA topological change
B	0003677	molecular_function	DNA binding
B	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
B	0005524	molecular_function	ATP binding
B	0006259	biological_process	DNA metabolic process
B	0006265	biological_process	DNA topological change
C	0003677	molecular_function	DNA binding
C	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
C	0005524	molecular_function	ATP binding
C	0006265	biological_process	DNA topological change
D	0003677	molecular_function	DNA binding
D	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
D	0005524	molecular_function	ATP binding
D	0006265	biological_process	DNA topological change

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue MFX F 101

Chain	Residue
B	SER81
C	GLU475
F	DG1
G	DT15
G	MG101
H	DC4
H	DA5

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site_id	AC2
Number of Residues	8
Details	binding site for residue MFX H 101

Chain	Residue
D	GLU475
E	DT15
F	DC4
F	DA5
H	DG1
H	MG102
A	SER81
D	ARG456

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site_id	AC3
Number of Residues	1
Details	binding site for residue MG H 102

Chain	Residue
H	MFX101

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site_id	AC4
Number of Residues	2
Details	binding site for residue MG G 101

Chain	Residue
F	MFX101
G	DT15

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Functional Information from PROSITE/UniProt

site_id	PS00177
Number of Residues	9
Details	TOPOISOMERASE_II DNA topoisomerase II signature. IVEGDSAGG

Chain	Residue	Details
C	ILE431-GLY439

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