4Z1Y

Thermostable enolase from Chloroflexus aurantiacus with substrate 2-phosphoglycerate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000015	cellular_component	phosphopyruvate hydratase complex
A	0000287	molecular_function	magnesium ion binding
A	0004634	molecular_function	phosphopyruvate hydratase activity
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0006096	biological_process	glycolytic process
A	0009986	cellular_component	cell surface
A	0016829	molecular_function	lyase activity
A	0046872	molecular_function	metal ion binding
B	0000015	cellular_component	phosphopyruvate hydratase complex
B	0000287	molecular_function	magnesium ion binding
B	0004634	molecular_function	phosphopyruvate hydratase activity
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0006096	biological_process	glycolytic process
B	0009986	cellular_component	cell surface
B	0016829	molecular_function	lyase activity
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue MG A 501

Chain	Residue
A	ASP243
A	GLU286
A	ASP313
A	2PG502

---

site_id	AC2
Number of Residues	7
Details	binding site for residue 2PG A 502

Chain	Residue
A	MG501
A	HOH611
A	GLU206
A	LYS338
A	ARG367
A	SER368
A	LYS389

---

site_id	AC3
Number of Residues	4
Details	binding site for residue MG B 501

Chain	Residue
B	ASP243
B	GLU286
B	ASP313
B	2PG502

---

site_id	AC4
Number of Residues	12
Details	binding site for residue 2PG B 502

Chain	Residue
B	ALA42
B	GLU206
B	ASP313
B	LEU336
B	LYS338
B	SER365
B	HIS366
B	ARG367
B	SER368
B	LYS389
B	MG501
B	HOH602

---

Functional Information from PROSITE/UniProt

site_id	PS00164
Number of Residues	14
Details	ENOLASE Enolase signature. ILIKlNQIGSLTET

Chain	Residue	Details
A	ILE335-THR348

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_00318","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00318","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PDB","id":"4Z17","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26082925","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26082925","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4Z17","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26082925","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4Z1Y","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00318","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"26082925","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4YWS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4Z17","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4Z1Y","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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